Frontline Science: Characterization of a novel mouse strain expressing human Siglec-8 only on eosinophils

Siglec-8 and Siglec-9 binding specificities and endogenous airway ligand distributions and properties

(2017) Huifeng Yu et al.   GLYCOBIOLOGY

Siglec-F is a novel intestinal M cell marker

(2016) Nadezhda Gicheva et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

“Siglec”ting the allergic response for therapeutic targeting

(2016) Bruce S Bochner   GLYCOBIOLOGY

IL-33 Precedes IL-5 in Regulating Eosinophil Commitment and Is Required for Eosinophil Homeostasis

(2016) Laura K. Johnston et al.   JOURNAL OF IMMUNOLOGY

Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites

(2016) François Gerbe et al.   NATURE

Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-8

(2016) Johannes M. Pröpster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of siglecs and related glycan-binding proteins in immune responses and immunoregulation

(2015) Bruce S. Bochner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis

(2015) Takumi Kiwamoto et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Expression of ligands for Siglec-8 and Siglec-9 in human airways and airway cells

(2015) Yi Jia et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Functionally Competent Eosinophils Differentiated Ex Vivo in High Purity from Normal Mouse Bone Marrow

(2014) K. D. Dyer et al.   JOURNAL OF IMMUNOLOGY

Mice deficient in the St3gal3 gene product α2,3 sialyltransferase (ST3Gal-III) exhibit enhanced allergic eosinophilic airway inflammation

(2013) Takumi Kiwamoto et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Galactose 6-O-Sulfotransferases Are Not Required for the Generation of Siglec-F Ligands in Leukocytes or Lung Tissue

(2013) Michael L. Patnode et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sialyltransferase ST3Gal-III Regulates Siglec-F Ligand Formation and Eosinophilic Lung Inflammation in Mice

(2013) M. Suzukawa et al.   JOURNAL OF IMMUNOLOGY

Homologous recombination into the eosinophil peroxidase locus generates a strain of mice expressing Cre recombinase exclusively in eosinophils

(2013) Alfred D. Doyle et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mechanisms of Siglec-F-Induced Eosinophil Apoptosis: A Role for Caspases but Not for SHP-1, Src Kinases, NADPH Oxidase or Reactive Oxygen

(2013) Hui Mao et al.   PLoS One

Siglec-8 as a drugable target to treat eosinophil and mast cell-associated conditions

(2012) Takumi Kiwamoto et al.   PHARMACOLOGY & THERAPEUTICS

Developmental, Malignancy-Related, and Cross-Species Analysis of Eosinophil, Mast Cell, and Basophil Siglec-8 Expression

(2011) Sherry A. Hudson et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Siglec-8 on human eosinophils and mast cells, and Siglec-F on murine eosinophils, are functionally related inhibitory receptors

(2009) B. S. Bochner   CLINICAL AND EXPERIMENTAL ALLERGY

Anti-Siglec-F antibody inhibits oral egg allergen induced intestinal eosinophilic inflammation in a mouse model

(2009) Dae Jin Song et al.   CLINICAL IMMUNOLOGY

Anti-Siglec-F Antibody Reduces Allergen-Induced Eosinophilic Inflammation and Airway Remodeling

(2009) D. J. Song et al.   JOURNAL OF IMMUNOLOGY

Eosinophil-Selective Binding and Proapoptotic Effect in Vitro of a Synthetic Siglec-8 Ligand, Polymeric 6'-Sulfated Sialyl Lewis X

(2009) S. A. Hudson et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Siglec-F antibody administration to mice selectively reduces blood and tissue eosinophils

(2008) N. Zimmermann et al.   ALLERGY

Interleukin-5 Priming of Human Eosinophils Alters Siglec-8–Mediated Apoptosis Pathways

(2007) Esra Nutku-Bilir et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY