MicroRNA miR-223 as regulator of innate immunity

Targeting Hypoxia Signaling for Perioperative Organ Injury

(2018) Xiaoyi Yuan et al.   ANESTHESIA AND ANALGESIA

The Hypoxia–Adenosine Link during Intestinal Inflammation

(2018) Jessica L. Bowser et al.   JOURNAL OF IMMUNOLOGY

BMSCs-derived miR-223-containing exosomes contribute to liver protection in experimental autoimmune hepatitis

(2018) Lu Chen et al.   MOLECULAR IMMUNOLOGY

The role of miRNA-223 in cancer: Function, diagnosis and therapy

(2017) Yunliang Gao et al.   GENE

Hepatic mitochondrial DNA/Toll-like receptor 9/MicroRNA-223 forms a negative feedback loop to limit neutrophil overactivation and acetaminophen hepatotoxicity in mice

(2017) Yong He et al.   HEPATOLOGY

The hypoxia-adenosine link during inflammation

(2017) Jessica L. Bowser et al.   JOURNAL OF APPLIED PHYSIOLOGY

Activation of MMPs in Macrophages by Mycobacterium tuberculosis via the miR-223-BMAL1 Signaling Pathway

(2017) Jun Lou et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome

(2017) Viola Neudecker et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MicroRNAs in mucosal inflammation

(2017) Viola Neudecker et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Novel therapeutic concepts for inflammatory bowel disease—from bench to bedside

(2017) Viola Neudecker et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Downregulated expression of miR-223 promotes Toll-like receptor-activated inflammatory responses in macrophages by targeting RhoB

(2017) Ningjie Zhang et al.   MOLECULAR IMMUNOLOGY

Neutrophil transfer of miR-223 to lung epithelial cells dampens acute lung injury in mice

(2017) Viola Neudecker et al.   Science Translational Medicine

Ly6G+ neutrophil-derived miR-223 inhibits the NLRP3 inflammasome in mitochondrial DAMP-induced acute lung injury

(2017) Zunyong Feng et al.   Cell Death & Disease

Emerging Roles for MicroRNAs in Perioperative Medicine

(2016) Viola Neudecker et al.   ANESTHESIOLOGY

The emerging role of miR-223 as novel potential diagnostic and therapeutic target for inflammatory disorders

(2016) Faisal Aziz   CELLULAR IMMUNOLOGY

MicroRNA-223 ameliorates alcoholic liver injury by inhibiting the IL-6–p47 phox –oxidative stress pathway in neutrophils

(2016) Man Li et al.   GUT

Extracellular vesicles: masters of intercellular communication and potential clinical interventions

(2016) Jonathan M. Pitt et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-223 controls the expression of histone deacetylase 2: a novel axis in COPD

(2016) Caroline Leuenberger et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

MicroRNAs Modulate the Purinergic Signaling Network

(2016) Davide Ferrari et al.   TRENDS IN MOLECULAR MEDICINE

Identification of microRNA biomarkers in type 2 diabetes: a meta-analysis of controlled profiling studies

(2015) Hongmei Zhu et al.   DIABETOLOGIA

miR-223 is upregulated in monocytes from patients with tuberculosis and regulates function of monocyte-derived macrophages

(2015) Yanhua Liu et al.   MOLECULAR IMMUNOLOGY

Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis

(2015) C M Aherne et al.   Mucosal Immunology

MicroRNA-223 Regulates the Differentiation and Function of Intestinal Dendritic Cells and Macrophages by Targeting C/EBPβ

(2015) Haibo Zhou et al.   Cell Reports

MicroRNA binding sites in the coding region of mRNAs: Extending the repertoire of post-transcriptional gene regulation

(2014) Anneke Brümmer et al.   BIOESSAYS

CD39 and CD161 Modulate Th17 Responses in Crohn's Disease

(2014) Aiping Bai et al.   JOURNAL OF IMMUNOLOGY

MiR-223-3p targeting SEPT6 promotes the biological behavior of prostate cancer

(2014) Yongbao Wei et al.   Scientific Reports

Transcriptional fine-tuning of microRNA-223 levels directs lineage choice of human hematopoietic progenitors

(2013) L Vian et al.   CELL DEATH AND DIFFERENTIATION

MicroRNA-223 controls susceptibility to tuberculosis by regulating lung neutrophil recruitment

(2013) Anca Dorhoi et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-223: infection, inflammation and cancer

(2013) M. Haneklaus et al.   JOURNAL OF INTERNAL MEDICINE

Treatment of HCV Infection by Targeting MicroRNA

(2013) Harry L.A. Janssen et al.   NEW ENGLAND JOURNAL OF MEDICINE

miRBase: annotating high confidence microRNAs using deep sequencing data

(2013) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

Morphine induced exacerbation of sepsis is mediated by tempering endotoxin tolerance through modulation of miR-146a

(2013) Santanu Banerjee et al.   Scientific Reports

microRNA Regulation of Inflammatory Responses

(2012) Ryan M. O'Connell et al.   Annual Review of Immunology

A Novel Regulator of Macrophage Activation

(2012) Guoqing Zhuang et al.   CIRCULATION

CD73 is a phenotypic marker of effector memory Th17 cells in inflammatory bowel disease

(2012) Glen A. Doherty et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

NLRP3 Inflammasome Activity Is Negatively Controlled by miR-223

(2012) F. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Purinergic Signaling during Inflammation

(2012) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inducible MicroRNA-223 Down-Regulation Promotes TLR-Triggered IL-6 and IL-1β Production in Macrophages by Targeting STAT3

(2012) Qingyun Chen et al.   PLoS One

Adenosine and Hypoxia-Inducible Factor Signaling in Intestinal Injury and Recovery

(2011) Sean P. Colgan et al.   Annual Review of Physiology

Selective Upregulation of microRNA Expression in Peripheral Blood Leukocytes in IL-10-/- Mice Precedes Expression in the Colon

(2011) J. S. Schaefer et al.   JOURNAL OF IMMUNOLOGY

Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells

(2011) Mei Yang et al.   Molecular Cancer

miRNA-223 Promotes Gastric Cancer Invasion and Metastasis by Targeting Tumor Suppressor EPB41L3

(2011) X. Li et al.   MOLECULAR CANCER RESEARCH

Alternative miRNA Biogenesis Pathways and the Interpretation of Core miRNA Pathway Mutants

(2011) Jr-Shiuan Yang et al.   MOLECULAR CELL

Ischemia and reperfusion—from mechanism to translation

(2011) Holger K Eltzschig et al.   NATURE MEDICINE

MicroRNA-223 expression in neutrophils in the early phase of secondary damage after spinal cord injury

(2011) Bunichiro Izumi et al.   NEUROSCIENCE LETTERS

Hypoxia and Inflammation

(2011) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Functional Disability 5 Years after Acute Respiratory Distress Syndrome

(2011) Margaret S. Herridge et al.   NEW ENGLAND JOURNAL OF MEDICINE

miR-122 activates hepatitis C virus translation by a specialized mechanism requiring particular RNA components

(2011) Ashley P. E. Roberts et al.   NUCLEIC ACIDS RESEARCH

Next-generation sequencing identifies the natural killer cell microRNA transcriptome

(2010) T. A. Fehniger et al.   GENOME RESEARCH

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

MicroRNAs modulate the noncanonical transcription factor NF-κB pathway by regulating expression of the kinase IKKα during macrophage differentiation

(2010) Tao Li et al.   NATURE IMMUNOLOGY

A Viral microRNA Down-Regulates Multiple Cell Cycle Genes through mRNA 5′UTRs

(2010) Finn Grey et al.   PLoS Pathogens

Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia

(2009) J. A. Pulikkan et al.   BLOOD

New class of microRNA targets containing simultaneous 5'-UTR and 3'-UTR interaction sites

(2009) I. Lee et al.   GENOME RESEARCH

miR-223 is overexpressed in T-lymphocytes of patients affected by rheumatoid arthritis

(2009) Valerio Fulci et al.   HUMAN IMMUNOLOGY

Cutting Edge: A2B Adenosine Receptor Signaling Provides Potent Protection during Intestinal Ischemia/Reperfusion Injury

(2009) M. L. Hart et al.   JOURNAL OF IMMUNOLOGY

Regulation of hepatitis C virus by microRNA-122: Figure 1

(2008) Catherine L. Jopling   BIOCHEMICAL SOCIETY TRANSACTIONS

MicroRNA-223 Is Commonly Repressed in Hepatocellular Carcinoma and Potentiates Expression of Stathmin1

(2008) Queenie W.–L. Wong et al.   GASTROENTEROLOGY

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Potential role of miR-9 and miR-223 in recurrent ovarian cancer

(2008) Alexandros Laios et al.   Molecular Cancer

Regulation of progenitor cell proliferation and granulocyte function by microRNA-223

(2008) Jonathan B. Johnnidis et al.   NATURE

MicroRNA-373 induces expression of genes with complementary promoter sequences

(2008) R. F. Place et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

microRNAs and the immune response

(2008) Mark A. Lindsay   TRENDS IN IMMUNOLOGY