Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling

Structural Mechanism for Cargo Recognition by the Retromer Complex

(2016) María Lucas et al.   CELL

Atypical parkinsonism–associated retromer mutant alters endosomal sorting of specific cargo proteins

(2016) Kirsty J. McMillan et al.   JOURNAL OF CELL BIOLOGY

DrosophilaWASH is required for integrin-mediated cell adhesion, cell motility and lysosomal neutralization

(2016) Benedikt M. Nagel et al.   JOURNAL OF CELL SCIENCE

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex

(2016) Thomas Clairfeuille et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

WASH drives early recycling from macropinosomes and phagosomes to maintain surface phagocytic receptors

(2016) Catherine M. Buckley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex

(2016) Thomas Clairfeuille et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Retromer and sorting nexins in endosomal sorting

(2015) Matthew Gallon et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Endocytic membrane trafficking and neurodegenerative disease

(2015) Andrea M. A. Schreij et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Endosomal sorting of Notch receptors through COMMD9-dependent pathways modulates Notch signaling

(2015) Haiying Li et al.   JOURNAL OF CELL BIOLOGY

COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A

(2015) Christine A. Phillips-Krawczak et al.   MOLECULAR BIOLOGY OF THE CELL

PANTHER version 10: expanded protein families and functions, and analysis tools

(2015) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

Expansion of Biological Pathways Based on Evolutionary Inference

(2014) Yang Li et al.   CELL

Retromer Binding to FAM21 and the WASH Complex Is Perturbed by the Parkinson Disease-Linked VPS35(D620N) Mutation

(2014) Ian J. McGough et al.   CURRENT BIOLOGY

Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration

(2014) E. Tsika et al.   HUMAN MOLECULAR GENETICS

Identification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recycling

(2014) I. J. McGough et al.   JOURNAL OF CELL SCIENCE

Sorting Nexin 31 Binds Multiple β Integrin Cytoplasmic Domains and Regulates β1 Integrin Surface Levels and Stability

(2014) Hui-Yuan Tseng et al.   JOURNAL OF MOLECULAR BIOLOGY

A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer

(2014) M. Gallon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retromer: A Master Conductor of Endosome Sorting

(2014) C. Burd et al.   Cold Spring Harbor Perspectives in Biology

Mutation in VPS35 associated with Parkinson’s disease impairs WASH complex association and inhibits autophagy

(2014) Eszter Zavodszky et al.   Nature Communications

A global analysis of SNX27–retromer assembly and cargo specificity reveals a function in glucose and metal ion transport

(2013) Florian Steinberg et al.   NATURE CELL BIOLOGY

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

(2013) R. Ghai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Sorting Nexin 17-Binding Domain Within the LRP1 Cytoplasmic Tail Mediates Receptor Recycling Through the Basolateral Sorting Endosome

(2013) Pamela Farfán et al.   TRAFFIC

Molecular basis for SNX-BAR-mediated assembly of distinct endosomal sorting tubules

(2012) Jan R T van Weering et al.   EMBO JOURNAL

SNX17 protects integrins from degradation by sorting between lysosomal and recycling pathways

(2012) Florian Steinberg et al.   JOURNAL OF CELL BIOLOGY

Multiple repeat elements within the FAM21 tail link the WASH actin regulatory complex to the retromer

(2012) Da Jia et al.   MOLECULAR BIOLOGY OF THE CELL

Sorting nexin 17 prevents lysosomal degradation of β1 integrins by binding to the β1-integrin tail

(2012) Ralph Thomas Böttcher et al.   NATURE CELL BIOLOGY

VPS35 Mutations in Parkinson Disease

(2011) Carles Vilariño-Güell et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Recruitment of the endosomal WASH complex is mediated by the extended ‘tail’ of Fam21 binding to the retromer protein Vps35

(2011) Michael E. Harbour et al.   BIOCHEMICAL JOURNAL

SNX3 controls Wingless/Wnt secretion through regulating retromer-dependent recycling of Wntless

(2011) Peng Zhang et al.   CELL RESEARCH

The ESCRT Pathway

(2011) William M. Henne et al.   DEVELOPMENTAL CELL

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

The Arp2/3 activator WASH regulates  5 1-integrin-mediated invasive migration

(2011) T. Zech et al.   JOURNAL OF CELL SCIENCE

Evolutionary reconstruction of the retromer complex and its function in Trypanosoma brucei

(2011) V. L. Koumandou et al.   JOURNAL OF CELL SCIENCE

A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion

(2011) Martin Harterink et al.   NATURE CELL BIOLOGY

SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors

(2011) Paul Temkin et al.   NATURE CELL BIOLOGY

Human Papillomavirus L2 Facilitates Viral Escape from Late Endosomes via Sorting Nexin 17

(2011) Martina Bergant Marušič et al.   TRAFFIC

Sequence-Dependent Sorting of Recycling Proteins by Actin-Stabilized Endosomal Microdomains

(2010) Manojkumar A. Puthenveedu et al.   CELL

SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane

(2010) Benjamin E.L. Lauffer et al.   JOURNAL OF CELL BIOLOGY

The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics

(2010) M. E. Harbour et al.   JOURNAL OF CELL SCIENCE

New baculovirus expression tools for recombinant protein complex production

(2010) Simon Trowitzsch et al.   JOURNAL OF STRUCTURAL BIOLOGY

The Arp2/3 Activator WASH Controls the Fission of Endosomes through a Large Multiprotein Complex

(2009) Emmanuel Derivery et al.   DEVELOPMENTAL CELL

A FAM21-Containing WASH Complex Regulates Retromer-Dependent Sorting

(2009) Timothy S. Gomez et al.   DEVELOPMENTAL CELL

Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5

(2009) M. N. J. Seaman et al.   JOURNAL OF CELL SCIENCE

Adaptor Protein Sorting Nexin 17 Regulates Amyloid Precursor Protein Trafficking and Processing in the Early Endosomes

(2008) Jiyeon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7

(2008) Raul Rojas et al.   JOURNAL OF CELL BIOLOGY

AP-1 and retromer play opposite roles in the trafficking of sortilin between the Golgi apparatus and the lysosomes

(2007) Maryssa Canuel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS