SNARE proteins in membrane trafficking

Essential role of STX6 in esophageal squamous cell carcinoma growth and migration

(2016) Jin Du et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Manganese exposure disrupts SNARE protein complex-mediated vesicle fusion in primary cultured neurons

(2016) Can Wang et al.   ENVIRONMENTAL TOXICOLOGY

Multiple ER–Golgi SNARE transmembrane domains are dispensable for trafficking but required for SNARE recycling

(2016) Li Chen et al.   MOLECULAR BIOLOGY OF THE CELL

The Vici Syndrome Protein EPG5 Is a Rab7 Effector that Determines the Fusion Specificity of Autophagosomes with Late Endosomes/Lysosomes

(2016) Zheng Wang et al.   MOLECULAR CELL

SNAP23 promotes the malignant process of ovarian cancer

(2016) Qi Sun et al.   Journal of Ovarian Research

Lipid Regulated Intramolecular Conformational Dynamics of SNARE-Protein Ykt6

(2016) Yawei Dai et al.   Scientific Reports

Synaptotagmin-1 C2B domain interacts simultaneously with SNAREs and membranes to promote membrane fusion

(2016) Shen Wang et al.   eLife

Impairment of autophagosome-lysosome fusion in the buff mutant mice with the VPS33AD251Emutation

(2015) Yuanli Zhen et al.   Autophagy

Drosophila p24 and Sec22 regulate Wingless trafficking in the early secretory pathway

(2015) Xue Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cryo-EM structure of SNAP-SNARE assembly in 20S particle

(2015) Qiang Zhou et al.   CELL RESEARCH

Three steps forward, two steps back: mechanistic insights into the assembly and disassembly of the SNARE complex

(2015) Jeffrey P Bombardier et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The Neurexin/N-Ethylmaleimide-sensitive Factor (NSF) Interaction Regulates Short Term Synaptic Depression

(2015) Tao Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The HabcDomain of the SNARE Vam3 Interacts with the HOPS Tethering Complex to Facilitate Vacuole Fusion

(2015) Anna Lürick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sec22 Regulates Endoplasmic Reticulum Morphology but Not Autophagy and Is Required for Eye Development inDrosophila

(2015) Xiaocui Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanistic insights into the recycling machine of the SNARE complex

(2015) Minglei Zhao et al.   NATURE

Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming

(2015) Xiaoyu Yang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Synaptosome-related (SNARE) genes and their interactions contribute to the susceptibility and working memory of attention-deficit/hyperactivity disorder in males

(2015) Qian Gao et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Spring-loaded unraveling of a single SNARE complex by NSF in one round of ATP turnover

(2015) J.-K. Ryu et al.   SCIENCE

A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly

(2015) R. W. Baker et al.   SCIENCE

Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming

(2015) Xiaoyu Yang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Munc18-1-regulated stage-wise SNARE assembly underlying synaptic exocytosis

(2015) Lu Ma et al.   eLife

Multiple conformations of a single SNAREpin between two nanodisc membranes reveal diverse pre-fusion states

(2014) Jaeil Shin et al.   BIOCHEMICAL JOURNAL

Syntaxin 8 Modulates the Post-synthetic Trafficking of the TrkA Receptor and Inflammatory Pain Transmission

(2014) Bing Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Three αSNAP and 10 ATP Molecules Are Used in SNARE Complex Disassembly byN-ethylmaleimide-sensitive Factor (NSF)

(2014) Niket Shah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spatial Control of Proton Pump H,K-ATPase Docking at the Apical Membrane by Phosphorylation-coupled Ezrin-Syntaxin 3 Interaction

(2014) Huijuan Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid Regulated Conformational Dynamics of the Longin SNARE Protein Ykt6 Revealed by Molecular Dynamics Simulations

(2014) Jingwei Weng et al.   JOURNAL OF PHYSICAL CHEMISTRY A

SNAP25 Ameliorates Sensory Deficit in Rats with Spinal Cord Transection

(2014) Wei Wang et al.   MOLECULAR NEUROBIOLOGY

O-GlcNAc-modification of SNAP-29 regulates autophagosome maturation

(2014) Bin Guo et al.   NATURE CELL BIOLOGY

VAMP8 facilitates cellular proliferation and temozolomide resistance in human glioma cells

(2014) Yuanyuan Chen et al.   NEURO-ONCOLOGY

Complexin inhibits spontaneous release and synchronizes Ca2+-triggered synaptic vesicle fusion by distinct mechanisms

(2014) Ying Lai et al.   eLife

SM proteins Sly1 and Vps33 co-assemble with Sec17 and SNARE complexes to oppose SNARE disassembly by Sec18

(2014) Braden T Lobingier et al.   eLife

Crystallization and preliminary X-ray diffraction analysis of Gos1p, a yeast SNARE protein

(2014) Baoyun Cheng et al.   Acta Crystallographica Section F-Structural Biology Communications

Visualization of Membrane Fusion, One Particle at a Time

(2013) Jason Otterstrom et al.   BIOCHEMISTRY

Single-molecule FRET study of SNARE-mediated membrane fusion

(2013) Jiajie Diao et al.   BIOSCIENCE REPORTS

The Golgi puppet master: COG complex at center stage of membrane trafficking interactions

(2013) Rose Willett et al.   HISTOCHEMISTRY AND CELL BIOLOGY

The COG complex interacts with multiple Golgi SNAREs and enhances fusogenic assembly of SNARE complexes

(2013) O. Laufman et al.   JOURNAL OF CELL SCIENCE

The Role of the N-D1 Linker of the N-Ethylmaleimide-Sensitive Factor in the SNARE Disassembly

(2013) Cui-Cui Liu et al.   PLoS One

The CORVET complex promotes tethering and fusion of Rab5/Vps21-positive membranes

(2013) H. J. k. Balderhaar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fusion pore formation and expansion induced by Ca2+and synaptotagmin 1

(2013) Ying Lai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tethering the assembly of SNARE complexes

(2013) WanJin Hong et al.   TRENDS IN CELL BIOLOGY

Mechanical unzipping and rezipping of a single SNARE complex reveals hysteresis as a force-generating mechanism

(2013) Duyoung Min et al.   Nature Communications

Golgi-SNARE GS28 potentiates cisplatin-induced apoptosis by forming GS28–MDM2–p53 complexes and by preventing the ubiquitination and degradation of p53

(2012) Nian-Kang Sun et al.   BIOCHEMICAL JOURNAL

The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes

(2012) Eisuke Itakura et al.   CELL

E3 ubiquitin ligase RNF13 involves spatial learning and assembly of the SNARE complex

(2012) Qiang Zhang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

How SNARE molecules mediate membrane fusion: Recent insights from molecular simulations

(2012) Herre Jelger Risselada et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Involvement of gecko SNAP25b in spinal cord regeneration by promoting outgrowth and elongation of neurites

(2012) Yingjie Wang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Structural characterization of full-length NSF and 20S particles

(2012) Lei-Fu Chang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

APPL1 potentiates insulin secretion in pancreatic   cells by enhancing protein kinase Akt-dependent expression of SNARE proteins in mice

(2012) K. K. Y. Cheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstitution of the Vital Functions of Munc18 and Munc13 in Neurotransmitter Release

(2012) C. Ma et al.   SCIENCE

Single Reconstituted Neuronal SNARE Complexes Zipper in Three Distinct Stages

(2012) Y. Gao et al.   SCIENCE

Exorcising the Exocyst Complex

(2012) Margaret R. Heider et al.   TRAFFIC

Cloning, expression, purification, crystallization and preliminary X-ray diffraction crystallographic study of human synaptotagmin 5 C2A domain

(2011) Xiaoting Qiu et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

OSBP-related protein 7 interacts with GATE-16 and negatively regulates GS28 protein stability

(2011) Wenbin Zhong et al.   EXPERIMENTAL CELL RESEARCH

The yeast Batten disease orthologue Btn1 controls endosome–Golgi retrograde transport via SNARE assembly

(2011) Rachel Kama et al.   JOURNAL OF CELL BIOLOGY

HOPS drives vacuole fusion by binding the vacuolar SNARE complex and the Vam7 PX domain via two distinct sites

(2011) Lukas Krämer et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of exocytosis by the exocyst subunit Sec6 and the SM protein Sec1

(2011) Francesca Morgera et al.   MOLECULAR BIOLOGY OF THE CELL

Munc13 mediates the transition from the closed syntaxin–Munc18 complex to the SNARE complex

(2011) Cong Ma et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Basolateral Sorting of Syntaxin 4 Is Dependent on Its N-terminal Domain and the AP1B Clathrin Adaptor, and Required for the Epithelial Cell Polarity

(2011) Elena Reales et al.   PLoS One

Epsin N-terminal homology domains bind on opposite sides of two SNAREs

(2011) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tethering Factors as Organizers of Intracellular Vesicular Traffic

(2010) I-Mei Yu et al.   Annual Review of Cell and Developmental Biology

UNC-31/CAPS docks and primes dense core vesicles in C. elegans neurons

(2010) Xian-Guang Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Multisubunit Tethering Complexes and Their Role in Membrane Fusion

(2010) Cornelia Bröcker et al.   CURRENT BIOLOGY

HOPS prevents the disassembly of trans-SNARE complexes by Sec17p/Sec18p during membrane fusion

(2010) Hao Xu et al.   EMBO JOURNAL

GSK-3  Inhibits Presynaptic Vesicle Exocytosis by Phosphorylating P/Q-Type Calcium Channel and Interrupting SNARE Complex Formation

(2010) L.-Q. Zhu et al.   JOURNAL OF NEUROSCIENCE

Ang2/Fat-Free Is a Conserved Subunit of the Golgi-associated Retrograde Protein Complex

(2010) F. Javier Pérez-Victoria et al.   MOLECULAR BIOLOGY OF THE CELL

HOPS Initiates Vacuole Docking by Tethering Membranes before trans-SNARE Complex Assembly

(2010) Christopher M. Hickey et al.   MOLECULAR BIOLOGY OF THE CELL

Lipid-Induced Conformational Switch Controls Fusion Activity of Longin Domain SNARE Ykt6

(2010) Wenyu Wen et al.   MOLECULAR CELL

An Electrostatically Preferred Lateral Orientation of SNARE Complex Suggests Novel Mechanisms for Driving Membrane Fusion

(2010) Ting Guo et al.   PLoS One

Dissection of SNARE-driven membrane fusion and neuroexocytosis by wedging small hydrophobic molecules into the SNARE zipper

(2010) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A fast, single-vesicle fusion assay mimics physiological SNARE requirements

(2010) Erdem Karatekin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transport according to GARP: receiving retrograde cargo at the trans-Golgi network

(2010) Juan S. Bonifacino et al.   TRENDS IN CELL BIOLOGY

Dual Roles of the Mammalian GARP Complex in Tethering and SNARE Complex Assembly at the trans-Golgi Network

(2009) F. J. Perez-Victoria et al.   MOLECULAR AND CELLULAR BIOLOGY

Membrane Fusion: Grappling with SNARE and SM Proteins

(2009) T. C. Sudhof et al.   SCIENCE

Vesicle Docking in Regulated Exocytosis

(2008) Matthijs Verhage et al.   TRAFFIC