Imaging of native transcription factors and histone phosphorylation at high resolution in live cells

Localization-based super-resolution imaging meets high-content screening

(2017) Anne Beghin et al.   NATURE METHODS

Identification of the elementary structural units of the DNA damage response

(2017) Francesco Natale et al.   Nature Communications

Targeting the replisome with transduced monoclonal antibodies triggers lethal DNA replication stress in cancer cells

(2016) Dominique Desplancq et al.   EXPERIMENTAL CELL RESEARCH

Intracellular Delivery of Nanobodies for Imaging of Target Proteins in Live Cells

(2016) Ruth Röder et al.   PHARMACEUTICAL RESEARCH

A single-molecule view of transcription reveals convoys of RNA polymerases and multi-scale bursting

(2016) Katjana Tantale et al.   Nature Communications

A dynamic mode of mitotic bookmarking by transcription factors

(2016) Sheila S Teves et al.   eLife

Labeling proteins inside living cells using external fluorophores for microscopy

(2016) Kai Wen Teng et al.   eLife

Super-resolution imaging of fluorescently labeled, endogenous RNA Polymerase II in living cells with CRISPR/Cas9-mediated gene editing

(2016) Won-Ki Cho et al.   Scientific Reports

Single-domain antibodies for biomedical applications

(2015) Simon Krah et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Persistent γH2AX: A promising molecular marker of DNA damage and aging

(2015) Mohammad Sabbir Siddiqui et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

CRISPR/Cas9-mediated endogenous protein tagging for RESOLFT super-resolution microscopy of living human cells

(2015) Michael Ratz et al.   Scientific Reports

SIMcheck: a Toolbox for Successful Super-resolution Structured Illumination Microscopy

(2015) Graeme Ball et al.   Scientific Reports

Recent applications of fluorescence correlation spectroscopy in live systems

(2014) Radek Macháň et al.   FEBS LETTERS

Specificity, polyspecificity, and heterospecificity of antibody-antigen recognition

(2014) Marc H. V. Van Regenmortel   JOURNAL OF MOLECULAR RECOGNITION

Delivery of antibodies to the cytosol

(2014) Andrea LJ Marschall et al.   mAbs

Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9

(2014) Shota Nakade et al.   Nature Communications

TANGO: a generic tool for high-throughput 3D image analysis for studying nuclear organization

(2013) Jean Ollion et al.   BIOINFORMATICS

The use of fluorescent intrabodies to detect endogenous gankyrin in living cancer cells

(2013) Anne-Sophie Rinaldi et al.   EXPERIMENTAL CELL RESEARCH

Targeting endogenous nuclear antigens by electrotransfer of monoclonal antibodies in living cells

(2013) Guillaume Freund et al.   mAbs

Spatial organization of RNA polymerase II inside a mammalian cell nucleus revealed by reflected light-sheet superresolution microscopy

(2013) Z. W. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Real-Time Dynamics of RNA Polymerase II Clustering in Live Human Cells

(2013) I. I. Cisse et al.   SCIENCE

Immunolabeling artifacts and the need for live-cell imaging

(2012) Ulrike Schnell et al.   NATURE METHODS

Quantitative Live Imaging of Endogenous DNA Replication in Mammalian Cells

(2012) Andrew Burgess et al.   PLoS One

Biogenesis of multisubunit RNA polymerases

(2012) Thomas Wild et al.   TRENDS IN BIOCHEMICAL SCIENCES

Targeting antibodies to the cytoplasm

(2011) Andrea L.J. Marschall et al.   mAbs

Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling

(2011) Yoko Hayashi-Takanaka et al.   NUCLEIC ACIDS RESEARCH

Nuclear proteins: finding and binding target sites in chromatin

(2010) Martin E. van Royen et al.   CHROMOSOME RESEARCH

Chromatin interaction of TATA-binding protein is dynamically regulated in human cells

(2010) P. de Graaf et al.   JOURNAL OF CELL SCIENCE

HSP90 and Its R2TP/Prefoldin-like Cochaperone Are Involved in the Cytoplasmic Assembly of RNA Polymerase II

(2010) Séverine Boulon et al.   MOLECULAR CELL

Transcription Dynamics

(2009) Gordon L. Hager et al.   MOLECULAR CELL

Golden Gate Shuffling: A One-Pot DNA Shuffling Method Based on Type IIs Restriction Enzymes

(2009) Carola Engler et al.   PLoS One

Modulation of RNA Polymerase Assembly Dynamics in Transcriptional Regulation

(2008) Stanislaw A. Gorski et al.   MOLECULAR CELL

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE

Subdiffraction Multicolor Imaging of the Nuclear Periphery with 3D Structured Illumination Microscopy

(2008) L. Schermelleh et al.   SCIENCE