A single-molecule view of transcription reveals convoys of RNA polymerases and multi-scale bursting

MS2 coat proteins bound to yeast mRNAs block 5' to 3' degradation and trap mRNA decay products: implications for the localization of mRNAs by MS2-MCP system

(2015) J. F. Garcia et al.   RNA

Mechanism of Transcriptional Bursting in Bacteria

(2014) Shasha Chong et al.   CELL

More pieces to the puzzle: recent structural insights into class II transcription initiation

(2014) Eaazhisai Kandiah et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes

(2014) Jason D Buenrostro et al.   NATURE BIOTECHNOLOGY

Transcription Factors Modulate c-Fos Transcriptional Bursts

(2014) Adrien Senecal et al.   Cell Reports

Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exons

(2014) Iris Jonkers et al.   eLife

Control of Transcriptional Elongation

(2013) Hojoong Kwak et al.   Annual Review of Genetics

Stochastic Fate Selection in HIV-Infected Patients

(2013) Ariel D. Weinberger et al.   CELL

Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure

(2013) Ya-Chi Ho et al.   CELL

The Mediator complex and transcription regulation

(2013) Zachary C. Poss et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Seeing Is Believing: Visualizing Transcriptional Dynamics in Single Cells

(2013) Alyshia Newhart et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Signaling Pathways Differentially Affect RNA Polymerase II Initiation, Pausing, and Elongation Rate in Cells

(2013) Charles G. Danko et al.   MOLECULAR CELL

FISH-quant: automatic counting of transcripts in 3D FISH images

(2013) Florian Mueller et al.   NATURE METHODS

Transcription-dependent dynamic supercoiling is a short-range genomic force

(2013) Fedor Kouzine et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An Experimental Verification of the Predicted Effects of Promoter TATA-Box Polymorphisms Associated with Human Diseases on Interactions between the TATA Boxes and TATA-Binding Protein

(2013) Ludmila Savinkova et al.   PLoS One

Genetic Determinants and Cellular Constraints in Noisy Gene Expression

(2013) A. Sanchez et al.   SCIENCE

Structural insights into transcription initiation by RNA polymerase II

(2013) Sebastian Grünberg et al.   TRENDS IN BIOCHEMICAL SCIENCES

Live-Cell Visualization of Pre-mRNA Splicing with Single-Molecule Sensitivity

(2013) Robert M. Martin et al.   Cell Reports

Genetic Selection for Context-Dependent Stochastic Phenotypes: Sp1 and TATA Mutations Increase Phenotypic Noise in HIV-1 Gene Expression

(2013) Kathryn Miller-Jensen et al.   PLoS Computational Biology

A structural perspective on Mediator function

(2012) Laurent Larivière et al.   CURRENT OPINION IN CELL BIOLOGY

Using Gene Expression Noise to Understand Gene Regulation

(2012) B. Munsky et al.   SCIENCE

Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation

(2011) Ute Schmidt et al.   JOURNAL OF CELL BIOLOGY

A transgenic mouse for in vivo detection of endogenous labeled mRNA

(2011) Timothée Lionnet et al.   NATURE METHODS

Chromatin interaction of TATA-binding protein is dynamically regulated in human cells

(2010) P. de Graaf et al.   JOURNAL OF CELL SCIENCE

Variability in gene expression underlies incomplete penetrance

(2010) Arjun Raj et al.   NATURE

RiboSys, a high-resolution, quantitative approach to measure the in vivo kinetics of pre-mRNA splicing and 3'-end processing in Saccharomyces cerevisiae

(2010) R. D. Alexander et al.   RNA

The basal initiation machinery: beyond the general transcription factors

(2009) Timothy W. Sikorski et al.   CURRENT OPINION IN CELL BIOLOGY

T7 RNA Polymerase Studied by Force Measurements Varying Cofactor Concentration

(2008) P. Thomen et al.   BIOPHYSICAL JOURNAL

Global Analysis of Host-Pathogen Interactions that Regulate Early-Stage HIV-1 Replication

(2008) Renate König et al.   CELL

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL

Nascent RNA Sequencing Reveals Widespread Pausing and Divergent Initiation at Human Promoters

(2008) Leighton J. Core et al.   SCIENCE

Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen

(2008) Abraham L. Brass et al.   SCIENCE