Localization-based super-resolution imaging meets high-content screening

Hippocampal LTP and contextual learning require surface diffusion of AMPA receptors

(2017) A. C. Penn et al.   NATURE

Super-resolution microscopy with DNA-PAINT

(2017) Joerg Schnitzbauer et al.   Nature Protocols

Photometry unlocks 3D information from 2D localization microscopy data

(2016) Christian Franke et al.   NATURE METHODS

Quantitative super-resolution imaging with qPAINT

(2016) Ralf Jungmann et al.   NATURE METHODS

High-density three-dimensional localization microscopy across large volumes

(2016) Wesley R Legant et al.   NATURE METHODS

Super-resolution imaging of multiple cells by optimized flat-field epi-illumination

(2016) Kyle M. Douglass et al.   Nature Photonics

Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes

(2016) Mark-Anthony Bray et al.   Nature Protocols

Highly photostable, reversibly photoswitchable fluorescent protein with high contrast ratio for live-cell superresolution microscopy

(2016) Xi Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Correlative light microscopy for high-content screening

(2016) Benjamin Flottmann et al.   BIOTECHNIQUES

Expression-Enhanced Fluorescent Proteins Based on Enhanced Green Fluorescent Protein for Super-resolution Microscopy

(2015) Sam Duwé et al.   ACS Nano

Dual-Color 3D Superresolution Microscopy by Combined Spectral-Demixing and Biplane Imaging

(2015) Christian M. Winterflood et al.   BIOPHYSICAL JOURNAL

Imaging Live-Cell Dynamics and Structure at the Single-Molecule Level

(2015) Zhe Liu et al.   MOLECULAR CELL

High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cells

(2015) Malte Wachsmuth et al.   NATURE BIOTECHNOLOGY

SR-Tesseler: a method to segment and quantify localization-based super-resolution microscopy data

(2015) Florian Levet et al.   NATURE METHODS

ThunderSTORM: a comprehensive ImageJ plug-in for PALM and STORM data analysis and super-resolution imaging

(2014) Martin Ovesný et al.   BIOINFORMATICS

Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion

(2014) Anaël Chazeau et al.   EMBO JOURNAL

High-density single-particle tracking: quantifying molecule organization and dynamics at the nanoscale

(2014) Jean-Baptiste Sibarita   HISTOCHEMISTRY AND CELL BIOLOGY

Integrated and correlative high-throughput and super-resolution microscopy

(2014) Manuel Gunkel et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Multiplexed 3D cellular super-resolution imaging with DNA-PAINT and Exchange-PAINT

(2014) Ralf Jungmann et al.   NATURE METHODS

High density 3D localization microscopy using sparse support recovery

(2014) Martin Ovesný et al.   OPTICS EXPRESS

High throughput 3D super-resolution microscopy reveals Caulobacter crescentus in vivo Z-ring organization

(2014) S. J. Holden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

3D high-density localization microscopy using hybrid astigmatic/ biplane imaging and sparse image reconstruction

(2014) Junhong Min et al.   Biomedical Optics Express

FALCON: fast and unbiased reconstruction of high-density super-resolution microscopy data

(2014) Junhong Min et al.   Scientific Reports

Super-Resolution Imaging Reveals That AMPA Receptors Inside Synapses Are Dynamically Organized in Nanodomains Regulated by PSD95

(2013) D. Nair et al.   JOURNAL OF NEUROSCIENCE

Real-Time Analysis and Visualization for Single-Molecule Based Super-Resolution Microscopy

(2013) Adel Kechkar et al.   PLoS One

Resolution Doubling in 3D-STORM Imaging through Improved Buffers

(2013) Nicolas Olivier et al.   PLoS One

Enzymatic Oxygen Scavenging for Photostability without pH Drop in Single-Molecule Experiments

(2012) Marko Swoboda et al.   ACS Nano

Automating Single Subunit Counting of Membrane Proteins in Mammalian Cells

(2012) Hugo McGuire et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of AMPA receptor surface trafficking and synaptic plasticity by a cognitive enhancer and antidepressant molecule

(2012) H Zhang et al.   MOLECULAR PSYCHIATRY

Rational design of true monomeric and bright photoactivatable fluorescent proteins

(2012) Mingshu Zhang et al.   NATURE METHODS

Chemically Induced Photoswitching of Fluorescent Probes—A General Concept for Super-Resolution Microscopy

(2011) Ulrike Endesfelder et al.   MOLECULES

Evaluation of fluorophores for optimal performance in localization-based super-resolution imaging

(2011) Graham T Dempsey et al.   NATURE METHODS

Direct stochastic optical reconstruction microscopy with standard fluorescent probes

(2011) Sebastian van de Linde et al.   Nature Protocols

Dynamic Superresolution Imaging of Endogenous Proteins on Living Cells at Ultra-High Density

(2010) Gregory Giannone et al.   BIOPHYSICAL JOURNAL

Make them Blink: Probes for Super-Resolution Microscopy

(2010) Jan Vogelsang et al.   CHEMPHYSCHEM

Single-Molecule Kinetics and Super-Resolution Microscopy by Fluorescence Imaging of Transient Binding on DNA Origami

(2010) Ralf Jungmann et al.   NANO LETTERS

Super-Resolution Imaging with Small Organic Fluorophores

(2009) Mike Heilemann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning

(2009) Thouis R. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CellProfiler Analyst: data exploration and analysis software for complex image-based screens

(2008) Thouis R Jones et al.   BMC BIOINFORMATICS

Subdiffraction-resolution fluorescence imaging of proteins in the mitochondrial inner membrane with photoswitchable fluorophores

(2008) Sebastian van de Linde et al.   JOURNAL OF STRUCTURAL BIOLOGY

High-density mapping of single-molecule trajectories with photoactivated localization microscopy

(2008) Suliana Manley et al.   NATURE METHODS

New Concepts in Synaptic Biology Derived from Single-Molecule Imaging

(2008) Antoine Triller et al.   NEURON

Surface Mobility of Postsynaptic AMPARs Tunes Synaptic Transmission

(2008) M. Heine et al.   SCIENCE

Three-Dimensional Super-Resolution Imaging by Stochastic Optical Reconstruction Microscopy

(2008) B. Huang et al.   SCIENCE

Microscopic imaging techniques for drug discovery

(2007) Andrew Bullen   NATURE REVIEWS DRUG DISCOVERY