Specificity, polyspecificity, and heterospecificity of antibody-antigen recognition

Automated Identification of Complementarity Determining Regions (CDRs) Reveals Peculiar Characteristics of CDRs and B Cell Epitopes

(2014) Y. Ofran et al.   JOURNAL OF IMMUNOLOGY

Using a Combined Computational-Experimental Approach to Predict Antibody-Specific B Cell Epitopes

(2014) Inbal Sela-Culang et al.   STRUCTURE

Antibody Polyreactivity in Health and Disease: Statu Variabilis

(2013) J. D. Dimitrov et al.   JOURNAL OF IMMUNOLOGY

Systematic, spatial imaging of large multimolecular assemblies and the emerging principles of supramolecular order in biological systems

(2013) Walter Schubert   JOURNAL OF MOLECULAR RECOGNITION

Crystal Structure of a Four-Layer Aggregate of Engineered TMV CP Implies the Importance of Terminal Residues for Oligomer Assembly

(2013) Xiangyang Li et al.   PLoS One

The indistinguishability of epitopes from protein surface is explained by the distinct binding preferences of each of the six antigen-binding loops

(2013) Vered Kunik et al.   PROTEIN ENGINEERING DESIGN & SELECTION

The Structural Basis of Antibody-Antigen Recognition

(2013) Inbal Sela-Culang et al.   Frontiers in Immunology

Structural Elucidation of the Mechanistic Basis of Degeneracy in the Primary Humoral Response

(2012) T. Khan et al.   JOURNAL OF IMMUNOLOGY

Antigen-binding site anatomy and somatic mutations in antibodies that recognize different types of antigens

(2012) Gopalan Raghunathan et al.   JOURNAL OF MOLECULAR RECOGNITION

An analysis of B-cell epitope discontinuity

(2012) Ganesh N. Sivalingam et al.   MOLECULAR IMMUNOLOGY

Structural analysis of B-cell epitopes in antibody:protein complexes

(2012) Jens Vindahl Kringelum et al.   MOLECULAR IMMUNOLOGY

Paratome: an online tool for systematic identification of antigen-binding regions in antibodies based on sequence or structure

(2012) Vered Kunik et al.   NUCLEIC ACIDS RESEARCH

SVMTriP: A Method to Predict Antigenic Epitopes Using Support Vector Machine to Integrate Tri-Peptide Similarity and Propensity

(2012) Bo Yao et al.   PLoS One

Determining germinal centre B cell fate

(2012) Dimitra Zotos et al.   TRENDS IN IMMUNOLOGY

Structural Consensus among Antibodies Defines the Antigen Binding Site

(2012) Vered Kunik et al.   PLoS Computational Biology

Basic research in HIV vaccinology is hampered by reductionist thinking

(2012) Marc H. V. Van Regenmortel   Frontiers in Immunology

Requirements for empirical immunogenicity trials, rather than structure-based design, for developing an effective HIV vaccine

(2011) Marc H. V. Van Regenmortel   ARCHIVES OF VIROLOGY

Prediction of conformational B-cell epitopes from 3D structures by random forests with a distance-based feature

(2011) Wen Zhang et al.   BMC BIOINFORMATICS

Polyreactive antibodies in adaptive immune responses to viruses

(2011) Hugo Mouquet et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Heterogeneous antigen recognition behavior of induced polyspecific antibodies

(2010) Jordan D. Dimitrov et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A New Clustering of Antibody CDR Loop Conformations

(2010) Benjamin North et al.   JOURNAL OF MOLECULAR BIOLOGY

Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

(2010) Hugo Mouquet et al.   NATURE

Evolving concepts of specificity in immune reactions

(2010) H. N. Eisen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use of amino acid composition to predict epitope residues of individual antibodies

(2010) Shinji Soga et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Few and Far Between: How HIV May Be Evading Antibody Avidity

(2010) Joshua S. Klein et al.   PLoS Pathogens

Prediction of antigenic epitopes on protein surfaces by consensus scoring

(2009) Shide Liang et al.   BMC BIOINFORMATICS

Structure-Activity Relationships in Peptide-Antibody Complexes: Implications for Epitope Prediction and Development of Synthetic Peptide Vaccines

(2009) Shu-wen Chen et al.   CURRENT MEDICINAL CHEMISTRY

Examination of the contributions of size and avidity to the neutralization mechanisms of the anti-HIV antibodies b12 and 4E10

(2009) J. S. Klein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Principles of Protein−Protein Interactions: What are the Preferred Ways For Proteins To Interact?

(2008) Ozlem Keskin et al.   CHEMICAL REVIEWS

Computational characterization of B-cell epitopes

(2007) Nimrod D. Rubinstein et al.   MOLECULAR IMMUNOLOGY

Benchmarking B cell epitope prediction: Underperformance of existing methods

(2004) Martin J. Blythe et al.   PROTEIN SCIENCE