Age-Dependent Changes to Sphingolipid Balance in the Human Hippocampus are Gender-Specific and May Sensitize to Neurodegeneration
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Title
Age-Dependent Changes to Sphingolipid Balance in the Human Hippocampus are Gender-Specific and May Sensitize to Neurodegeneration
Authors
Keywords
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Journal
JOURNAL OF ALZHEIMERS DISEASE
Volume 63, Issue 2, Pages 503-514
Publisher
IOS Press
Online
2018-04-13
DOI
10.3233/jad-171054
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Note: Only part of the references are listed.- Profiling Brain and Plasma Lipids in Human APOE ε2, ε3, and ε4 Knock-in Mice Using Electrospray Ionization Mass Spectrometry
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- (2014) Saul A Villeda et al. NATURE MEDICINE
- Clinical epidemiology of Alzheimer’s disease: assessing sex and gender differences
- (2014) Michelle Mielke et al. Clinical Epidemiology
- Loss of the neuroprotective factor Sphingosine 1-phosphate early in Alzheimer’s disease pathogenesis
- (2014) Timothy A Couttas et al. Acta Neuropathologica Communications
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- The global prevalence of dementia: A systematic review and metaanalysis
- (2013) Martin Prince et al. Alzheimers & Dementia
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- (2013) Alzheimers & Dementia
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- (2013) Kohei Yuyama et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
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- (2013) Hila Zigdon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
- (2013) Chia-Chen Liu et al. Nature Reviews Neurology
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- (2012) M. Kosicek et al. NEUROSCIENCE LETTERS
- MMSAT: Automated Quantification of Metabolites in Selected Reaction Monitoring Experiments
- (2011) Jason W. H. Wong et al. ANALYTICAL CHEMISTRY
- Activation of sphingosine kinase 2 is an endogenous protective mechanism in cerebral ischemia
- (2011) Waltraud Pfeilschifter et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- Sphingolipid and Glycosphingolipid Metabolic Pathways in the Era of Sphingolipidomics
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- Comparative Lipidomic Analysis of Mouse and Human Brain with Alzheimer Disease
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- Metabolomics in Early Alzheimer's Disease: Identification of Altered Plasma Sphingolipidome Using Shotgun Lipidomics
- (2011) Xianlin Han et al. PLoS One
- Alzheimer's Disease: The Challenge of the Second Century
- (2011) D. M. Holtzman et al. Science Translational Medicine
- A Deficiency of Ceramide Biosynthesis Causes Cerebellar Purkinje Cell Neurodegeneration and Lipofuscin Accumulation
- (2011) Lihong Zhao et al. PLoS Genetics
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- (2010) Jean E. Vance et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
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- (2008) Xingxuan He et al. NEUROBIOLOGY OF AGING
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