The Initiation of Th2 Immunity Towards Food Allergens

Association of STAT6 gene variants with food allergy diagnosed by double-blind placebo-controlled food challenges

(2018) C. D. van Ginkel et al.   ALLERGY

Modified Allergens for Immunotherapy

(2018) Pattraporn Satitsuksanoa et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Assessment of the Allergenic Potential of the Main Egg White Proteins in BALB/c Mice

(2018) Alba Pablos-Tanarro et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Mechanism for initiation of food allergy: Dependence on skin barrier mutations and environmental allergen costimulation

(2018) Matthew T. Walker et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Disruption of the Epidermal Barrier Induces Regulatory T Cells via IL-33 in Mice

(2018) Anika Bruhs et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Food allergy: is prevalence increasing?

(2017) Mimi L. K. Tang et al.   INTERNAL MEDICINE JOURNAL

Additional effects of dietary advanced glycation end products

(2017) Jeffrey D. Miller   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Early life innate immune signatures of persistent food allergy

(2017) Melanie R. Neeland et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The false alarm hypothesis: Food allergy is associated with high dietary advanced glycation end-products and proglycating dietary sugars that mimic alarmins

(2017) Peter K. Smith et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Airway exposure initiates peanut allergy by involving the IL-1 pathway and T follicular helper cells in mice

(2017) Joseph J. Dolence et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Epicutaneous immunotherapy induces gastrointestinal LAP + regulatory T cells and prevents food-induced anaphylaxis

(2017) Leticia Tordesillas et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lifelong memory responses perpetuate humoral T H 2 immunity and anaphylaxis in food allergy

(2017) Rodrigo Jiménez-Saiz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Detection of peanut allergen in human blood after consumption of peanuts is skewed by endogenous immunoglobulins

(2017) Lonneke M. JanssenDuijghuijsen et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Intradermal administration of IL-33 induces allergic airway inflammation

(2017) Hongwei Han et al.   Scientific Reports

IL-4 production by group 2 innate lymphoid cells promotes food allergy by blocking regulatory T-cell function

(2016) Magali Noval Rivas et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Does atopic dermatitis cause food allergy? A systematic review

(2016) Teresa Tsakok et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Subcutaneous Allergic Sensitization to Protease Allergen Is Dependent on Mast Cells but Not IL-33: Distinct Mechanisms between Subcutaneous and Intranasal Routes

(2016) Seiji Kamijo et al.   JOURNAL OF IMMUNOLOGY

Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children

(2016) Michelle M. Stein et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cesarean section delivery and development of food allergy and atopic dermatitis in early childhood

(2016) Evangelia Papathoma et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Transcriptional Profiling of Egg Allergy and Relationship to Disease Phenotype

(2016) Roman Kosoy et al.   PLoS One

Dietary antigens limit mucosal immunity by inducing regulatory T cells in the small intestine

(2016) K. S. Kim et al.   SCIENCE

Trained immunity: A program of innate immune memory in health and disease

(2016) M. G. Netea et al.   SCIENCE

Cord blood monocyte–derived inflammatory cytokines suppress IL-2 and induce nonclassic “T H 2-type” immunity associated with development of food allergy

(2016) Yuxia Zhang et al.   Science Translational Medicine

CD80 and CD86 knockdown in dendritic cells regulates Th1/Th2 cytokine production in asthmatic mice

(2016) JIAN-GUO LI et al.   Experimental and Therapeutic Medicine

Food allergy in atopic dermatitis

(2016) Sandipan Dhar et al.   INDIAN JOURNAL OF DERMATOLOGY

Regulation of IgE-Mediated Food Allergy by IL-9 Producing Mucosal Mast Cells and Type 2 Innate Lymphoid Cells

(2016) Jee-Boong Lee   Immune Network

Impaired Tight Junctions in Atopic Dermatitis Skin and in a Skin-Equivalent Model Treated with Interleukin-17

(2016) Takuo Yuki et al.   PLoS One

Comprehensive metabolomics identifies the alarmin uric acid as a critical signal for the induction of peanut allergy

(2015) J. Kong et al.   ALLERGY

What makes an allergen?

(2015) S. Scheurer et al.   CLINICAL AND EXPERIMENTAL ALLERGY

History of interleukin-4

(2015) William E. Paul   CYTOKINE

Food processing and allergenicity

(2015) Kitty C.M. Verhoeckx et al.   FOOD AND CHEMICAL TOXICOLOGY

Barrier Epithelial Cells and the Control of Type 2 Immunity

(2015) Hamida Hammad et al.   IMMUNITY

Food allergy in patients with primary immunodeficiency diseases: Prevalence within the US Immunodeficiency Network (USIDNET)

(2015) Karen S. Tuano et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy

(2015) Helen A. Brough et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Papain Degrades Tight Junction Proteins of Human Keratinocytes In Vitro and Sensitizes C57BL/6 Mice via the Skin Independent of its Enzymatic Activity or TLR4 Activation

(2015) Caroline Stremnitzer et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The immunology of asthma

(2015) Bart N Lambrecht et al.   NATURE IMMUNOLOGY

Adjusting for nonresponse bias corrects overestimates of food allergy prevalence

(2015) Lianne Soller et al.   Journal of Allergy and Clinical Immunology-In Practice

Detailed characterization of Act d 12 and Act d 13 from kiwi seeds: implication in IgE cross-reactivity with peanut and tree nuts

(2014) S. Sirvent et al.   ALLERGY

Effect of Processing Technologies on the Allergenicity of Food Products

(2014) Rodrigo Jiménez-Saiz et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Skin Barrier Defects in Atopic Dermatitis

(2014) Rachana Agrawal et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Cutaneous or Respiratory Exposures to Peanut Allergens in Mice and Their Impacts on Subsequent Oral Exposure

(2014) Sophie Wavrin et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

The role of basophils and proallergic cytokines, TSLP and IL-33, in cutaneously sensitized food allergy

(2014) T. Muto et al.   INTERNATIONAL IMMUNOLOGY

Food allergy: Insights into etiology, prevention, and treatment provided by murine models

(2014) Michiko K. Oyoshi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment

(2014) Scott H. Sicherer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin–basophil axis

(2014) Mario Noti et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Ovalbumin Modified with Pyrraline, a Maillard Reaction Product, shows Enhanced T-cell Immunogenicity

(2014) Monika Heilmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thymic stromal lymphopoietin–mediated epicutaneous inflammation promotes acute diarrhea and anaphylaxis

(2014) Hongwei Han et al.   JOURNAL OF CLINICAL INVESTIGATION

Skin exposure promotes a Th2-dependent sensitization to peanut allergens

(2014) Leticia Tordesillas et al.   JOURNAL OF CLINICAL INVESTIGATION

Indigenous enteric eosinophils control DCs to initiate a primary Th2 immune response in vivo

(2014) Derek K. Chu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Gastrointestinal Dendritic Cells Promote Th2 Skewing via OX40L

(2014) A. B. Blazquez et al.   JOURNAL OF IMMUNOLOGY

Airway Uric Acid Is a Sensor of Inhaled Protease Allergens and Initiates Type 2 Immune Responses in Respiratory Mucosa

(2014) K. Hara et al.   JOURNAL OF IMMUNOLOGY

T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes

(2014) D K Chu et al.   Mucosal Immunology

Staphylococcus aureusand Staphylococcal Food-Borne Disease: An Ongoing Challenge in Public Health

(2014) Jhalka Kadariya et al.   Biomed Research International

Priming Dendritic Cells for Th2 Polarization: Lessons Learned from Helminths and Implications for Metabolic Disorders

(2014) Leonie Hussaarts et al.   Frontiers in Immunology

Allergic sensitization: food- and protein-related factors

(2014) Scott McClain et al.   Clinical and Translational Allergy

Relationship between treatment with antacid medication and the prevalence of food allergy in children

(2013) Karen DeMuth et al.   ALLERGY AND ASTHMA PROCEEDINGS

Did Cholera Toxin Finally Get Caught?

(2013) Fabio Martinon et al.   Cell Host & Microbe

Direct interaction between cholera toxin and dendritic cells is required for oral adjuvant activity

(2013) Tobias Gustafsson et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Epicutaneous sensitization results in IgE-dependent intestinal mast cell expansion and food-induced anaphylaxis

(2013) Lisa M. Bartnikas et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Allergens as Immunomodulatory Proteins: The Cat Dander Protein Fel d 1 Enhances TLR Activation by Lipid Ligands

(2013) J. Herre et al.   JOURNAL OF IMMUNOLOGY

Leishmania majorinhibits IL-12 in macrophages by signalling through CR3 (CD11b/CD18) and down-regulation of ETS-mediated transcription

(2013) C. Ricardo-Carter et al.   PARASITE IMMUNOLOGY

Mechanisms of Action of Adjuvants

(2013) Sunita Awate et al.   Frontiers in Immunology

Thymic stromal lymphopoietin expression is increased in the horny layer of patients with atopic dermatitis

(2012) Y. Sano et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Overall prevalence of self-reported food allergy in Canada

(2012) Lianne Soller et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization

(2012) Derek K. Chu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A microbiota signature associated with experimental food allergy promotes allergic sensitization and anaphylaxis

(2012) Magali Noval Rivas et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4

(2012) Yvonne Junker et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-33 and ST2 in Atopic Dermatitis: Expression Profiles and Modulation by Triggering Factors

(2012) Terhi Savinko et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Oral tolerance to food protein

(2012) O Pabst et al.   Mucosal Immunology

Innate immunostimulatory properties of allergens and their relevance to food allergy

(2012) Bert Ruiter et al.   Seminars in Immunopathology

Food allergies in developing and emerging economies: need for comprehensive data on prevalence rates

(2012) Joyce Irene Boye   Clinical and Translational Allergy

IgE-binding epitopes: a reappraisal

(2011) R. C. Aalberse et al.   ALLERGY

IL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiation

(2011) Wei Liao et al.   CURRENT OPINION IN IMMUNOLOGY

The genetics of asthma and allergic disease: a 21st century perspective

(2011) Carole Ober et al.   IMMUNOLOGICAL REVIEWS

Factors influencing the allergenicity and adjuvanticity of allergens

(2011) Stephan Deifl et al.   Immunotherapy

Immunomodulatory Effects of Heated Ovomucoid-Depleted Egg White in a BALB/c Mouse Model of Egg Allergy

(2011) Rodrigo Jiménez-Saiz et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Invariant natural killer T cells from children with versus without food allergy exhibit differential responsiveness to milk-derived sphingomyelin

(2011) Soma Jyonouchi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Allergic sensitization can be induced via multiple physiologic routes in an adjuvant-dependent manner

(2011) David Dunkin et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy

(2011) Sara J. Brown et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A Small Molecule That Mimics the BB-loop in the Toll Interleukin-1 (IL-1) Receptor Domain of MyD88 Attenuates Staphylococcal Enterotoxin B-induced Pro-inflammatory Cytokine Production and Toxicity in Mice

(2011) Teri L. Kissner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antibiotic use in early life and development of allergic diseases: respiratory infection as the explanation

(2010) X.-M. Mai et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Management of the Patient with Multiple Food Allergies

(2010) Julie Wang   CURRENT ALLERGY AND ASTHMA REPORTS

What determines Th2 differentiation, in vitro and in vivo ?

(2010) William E Paul   IMMUNOLOGY AND CELL BIOLOGY

Guilt by intimate association: What makes an allergen an allergen?

(2010) Christopher L. Karp   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mechanical injury polarizes skin dendritic cells to elicit a TH2 response by inducing cutaneous thymic stromal lymphopoietin expression

(2010) Michiko K. Oyoshi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The Mannose Receptor Mediates the Uptake of Diverse Native Allergens by Dendritic Cells and Determines Allergen-Induced T Cell Polarization through Modulation of IDO Activity

(2010) P.-J. Royer et al.   JOURNAL OF IMMUNOLOGY

Structure, biological functions and applications of the AB5 toxins

(2010) Travis Beddoe et al.   TRENDS IN BIOCHEMICAL SCIENCES

Genetics of food allergy

(2009) Xiumei Hong et al.   CURRENT OPINION IN PEDIATRICS

Glycation of a food allergen by the Maillard reaction enhances its T-cell immunogenicity: Role of macrophage scavenger receptor class A type I and II

(2009) Anne Ilchmann et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Filaggrin in the frontline: role in skin barrier function and disease

(2009) A. Sandilands et al.   JOURNAL OF CELL SCIENCE

The role of protein digestibility and antacids on food allergy outcomes

(2008) Eva Untersmayr et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Allergens are distributed into few protein families and possess a restricted number of biochemical functions

(2008) Christian Radauer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Impairing oral tolerance promotes allergy and anaphylaxis: A new murine food allergy model

(2008) Kirthana Ganeshan et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation

(2008) N. van Panhuys et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA