A continuous flow approach for the C–H functionalization of 1,2,3-triazoles in γ-valerolactone as a biomass-derived medium

The synthesis, antifungal and apoptotic effects of triazole-oxadiazoles against Candida species

(2018) Betül Kaya Çavuşoğlu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Exploration of 1,2,3-triazole-pyrimidine hybrids as potent reversal agents against ABCB1-mediated multidrug resistance

(2018) Bo Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Waste-minimised copper-catalysed azide–alkyne cycloaddition in Polarclean as a reusable and safe reaction medium

(2018) Lorenzo Luciani et al.   GREEN CHEMISTRY

Ruthenium(ii) oxidase catalysis for C–H alkenylations in biomass-derived γ-valerolactone

(2018) Alexander Bechtoldt et al.   GREEN CHEMISTRY

Definition of green synthetic tools based on safer reaction media, heterogeneous catalysis, and flow technology

(2018) Luigi Vaccaro et al.   PURE AND APPLIED CHEMISTRY

Design, synthesis and biological evaluation of tacrine-1,2,3-triazole derivatives as potent cholinesterase inhibitors

(2018) Gaochan Wu et al.   MedChemComm

Transient Directing Groups for Transformative C–H Activation by Synergistic Metal Catalysis

(2018) Parthasarathy Gandeepan et al.   Chem

Biomass-derived solvents as effective media for cross-coupling reactions and C–H functionalization processes

(2017) Stefano Santoro et al.   GREEN CHEMISTRY

Heterogeneous C–H alkenylations in continuous-flow: oxidative palladium-catalysis in a biomass-derived reaction medium

(2017) Francesco Ferlin et al.   GREEN CHEMISTRY

Design, Synthesis, Characterization, and Antimicrobial Evaluation of Novel 2-(3, 5-di methoxy-4-((1-aryl-1H -1, 2, 3-triazole-4-yl) methoxy) phenyl) benzo[d ]thiazoles

(2017) Subhashini N.J.P. et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Electrochemical Cobalt-Catalyzed C–H Oxygenation at Room Temperature

(2017) Nicolas Sauermann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver(I)-Catalyzed Regioselective Synthesis of Triazole Fused-1,5-Benzoxazocinones

(2017) Indrajeet J. Barve et al.   ORGANIC LETTERS

Selective C(sp2)–H Halogenation of “Click” 4-Aryl-1,2,3-triazoles

(2017) Asier Goitia et al.   ORGANIC LETTERS

Discovery of potential antifungal triazoles: design, synthesis, biological evaluation, and preliminary antifungal mechanism exploration

(2017) Yuan Zhang et al.   MedChemComm

Recent advances in positional-selective alkenylations: removable guidance for twofold C–H activation

(2017) Wenbo Ma et al.   Organic Chemistry Frontiers

Synthesis of β-Cyano Ketones Promoted by a Heterogeneous Fluoride Catalyst

(2016) Giacomo Strappaveccia et al.   ADVANCED SYNTHESIS & CATALYSIS

A Simple and Versatile Amide Directing Group for C−H Functionalizations

(2016) Ru-Yi Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C–H arylations of 1,2,3-triazoles by reusable heterogeneous palladium catalysts in biomass-derived γ-valerolactone

(2016) Xu Tian et al.   CHEMICAL COMMUNICATIONS

Regioselective synthesis of multisubstituted 1,2,3-triazoles: moving beyond the copper-catalyzed azide–alkyne cycloaddition

(2016) Fang Wei et al.   CHEMICAL COMMUNICATIONS

Palladium-Catalyzed Transformations of Alkyl C–H Bonds

(2016) Jian He et al.   CHEMICAL REVIEWS

Enantioselective syntheses of indanes: from organocatalysis to C–H functionalization

(2016) Cyril Borie et al.   CHEMICAL SOCIETY REVIEWS

Mild metal-catalyzed C–H activation: examples and concepts

(2016) T. Gensch et al.   CHEMICAL SOCIETY REVIEWS

Ag-catalyzed C–H/C–C bond functionalization

(2016) Qing-Zhong Zheng et al.   CHEMICAL SOCIETY REVIEWS

Synthesis of γ-Valerolactone from Carbohydrates and its Applications

(2016) Zehui Zhang   ChemSusChem

Searching for novel reusable biomass-derived solvents: furfuryl alcohol/water azeotrope as a medium for waste-minimised copper-catalysed azide–alkyne cycloaddition

(2016) Dace Rasina et al.   GREEN CHEMISTRY

A step towards hydroformylation under sustainable conditions: platinum-catalysed enantioselective hydroformylation of styrene in gamma-valerolactone

(2016) Péter Pongrácz et al.   GREEN CHEMISTRY

Updating and further expanding GSK's solvent sustainability guide

(2016) Catherine M. Alder et al.   GREEN CHEMISTRY

CHEM21 selection guide of classical- and less classical-solvents

(2016) Denis Prat et al.   GREEN CHEMISTRY

Copper(I)-Catalyzed Three-Component Click/Alkynylation: One-Pot Synthesis of 5-Alkynyl-1,2,3-triazoles

(2016) Weiguo Wang et al.   ORGANIC LETTERS

Toward a More Holistic Framework for Solvent Selection

(2016) Louis J. Diorazio et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Click-chemistry approaches to π-conjugated polymers for organic electronics applications

(2016) Assunta Marrocchi et al.   Chemical Science

Copper Nanoparticles in Click Chemistry

(2015) Francisco Alonso et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chiral Cyclopentadienyls: Enabling Ligands for Asymmetric Rh(III)-Catalyzed C–H Functionalizations

(2015) Baihua Ye et al.   ACCOUNTS OF CHEMICAL RESEARCH

Copper(I)-Catalyzed Interrupted Click Reaction: Synthesis of Diverse 5-Hetero-Functionalized Triazoles

(2015) Weiguo Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Novel cross-linked polystyrenes with large space network as tailor-made catalyst supports for sustainable media

(2015) Assunta Marrocchi et al.   EUROPEAN POLYMER JOURNAL

Life cycle inventory improvement in the pharmaceutical sector: assessment of the sustainability combining PMI and LCA tools

(2015) Daniele Cespi et al.   GREEN CHEMISTRY

A biomass-derived safe medium to replace toxic dipolar solvents and access cleaner Heck coupling reactions

(2015) Giacomo Strappaveccia et al.   GREEN CHEMISTRY

γ-Valerolactone as an alternative biomass-derived medium for the Sonogashira reaction

(2015) Giacomo Strappaveccia et al.   GREEN CHEMISTRY

Pd-Catalyzed Regioselective Arylation on the C-5 Position of N-Aryl 1,2,3-Triazoles

(2015) K. Durga Bhaskar Yamajala et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-catalysed azide–alkyne cycloadditions (CuAAC): an update

(2015) Estela Haldón et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cu/Pd-Catalyzed, Three-Component Click Reaction of Azide, Alkyne, and Aryl Halide: One-Pot Strategy toward Trisubstituted Triazoles

(2015) Fang Wei et al.   ORGANIC LETTERS

An Efficient and Waste-Minimized One-Pot Procedure for the Preparation of N-Boc-γ-amino Alcohols Starting from α,β-Unsaturated Ketones in Flow

(2015) Eleonora Ballerini et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Waste Minimized Multistep Preparation in Flow of β-Amino Acids Starting from α,β-Unsaturated Carboxylic Acids

(2015) Eleonora Ballerini et al.   ACS Sustainable Chemistry & Engineering

Aquivion PFSA as a Novel Solid and Reusable Acid Catalyst in the Synthesis of 2-Pyrrolidin-2-ones in Flow

(2015) Luca Bianchi et al.   ACS Sustainable Chemistry & Engineering

A survey of solvent selection guides

(2014) Denis Prat et al.   GREEN CHEMISTRY

Flow approaches towards sustainability

(2014) Luigi Vaccaro et al.   GREEN CHEMISTRY

Catalytic Conversion of Fructose, Glucose, and Sucrose to 5-(Hydroxymethyl)furfural and Levulinic and Formic Acids in γ-Valerolactone As a Green Solvent

(2014) Long Qi et al.   ACS Catalysis

γ-Valerolactone as a Renewable Dipolar Aprotic Solvent Deriving from Biomass Degradation for the Hiyama Reaction

(2014) Ermal Ismalaj et al.   ACS Sustainable Chemistry & Engineering

Ln[N(SiMe3)2]3-catalyzed cycloaddition of terminal alkynes to azides leading to 1,5-disubstituted 1,2,3-triazoles: new mechanistic features

(2013) Longcheng Hong et al.   CHEMICAL COMMUNICATIONS

C–H bond activation enables the rapid construction and late-stage diversification of functional molecules

(2013) Joanna Wencel-Delord et al.   Nature Chemistry

Halogen Exchange (Halex) Reaction of 5-Iodo-1,2,3-triazoles: Synthesis and Applications of 5-Fluorotriazoles

(2012) Brady T. Worrell et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Conversion of Hemicellulose into Furfural Using Solid Acid Catalysts in γ-Valerolactone

(2012) Elif I. Gürbüz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-catalyzed CuAAC/intramolecular C–H arylation sequence: Synthesis of annulated 1,2,3-triazoles

(2012) Rajkumar Jeyachandran et al.   Beilstein Journal of Organic Chemistry

Production of levulinic acid and gamma-valerolactone (GVL) from cellulose using GVL as a solvent in biphasic systems

(2012) Stephanie G. Wettstein et al.   Energy & Environmental Science

Highly efficient synthesis of phosphatidylserine in the eco-friendly solvent γ-valerolactone

(2012) Zhang-Qun Duan et al.   GREEN CHEMISTRY

High-valent organometallic copper and palladium in catalysis

(2012) Amanda J. Hickman et al.   NATURE

Catalytic Conversion of Fructose to γ-Valerolactone in γ-Valerolactone

(2012) Long Qi et al.   ACS Catalysis

Click Dendrimers and Triazole-Related Aspects: Catalysts, Mechanism, Synthesis, and Functions. A Bridge between Dendritic Architectures and Nanomaterials

(2011) Didier Astruc et al.   ACCOUNTS OF CHEMICAL RESEARCH

Expanding GSK's solvent selection guide – embedding sustainability into solvent selection starting at medicinal chemistry

(2011) Richard K. Henderson et al.   GREEN CHEMISTRY

Searching for green solvents

(2011) Philip G. Jessop   GREEN CHEMISTRY

E-factor minimized protocols for the polystyryl-BEMP catalyzed conjugate additions of various nucleophiles to α,β-unsaturated carbonyl compounds

(2011) Simona Bonollo et al.   GREEN CHEMISTRY

Using the Right Green Yardstick: Why Process Mass Intensity Is Used in the Pharmaceutical Industry To Drive More Sustainable Processes

(2011) Concepcion Jimenez-Gonzalez et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Click polymerization

(2010) Anjun Qin et al.   CHEMICAL SOCIETY REVIEWS

Click chemistry with DNA

(2010) Afaf H. El-Sagheer et al.   CHEMICAL SOCIETY REVIEWS

An E-factor minimized protocol for the preparation of methyl β-hydroxy esters

(2010) Francesco Fringuelli et al.   GREEN CHEMISTRY

Regioselective syntheses of fully-substituted 1,2,3-triazoles: the CuAAC/C–H bond functionalization nexus

(2010) Lutz Ackermann et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Palladium-Catalyzed Dehydrogenative Direct Arylations of 1,2,3-Triazoles

(2010) Lutz Ackermann et al.   ORGANIC LETTERS

The application of CuAAC ‘click’ chemistry to catenane and rotaxane synthesis

(2009) Kevin D. Hänni et al.   CHEMICAL SOCIETY REVIEWS

Copper-Mediated Direct Arylation of 1,3,4-Oxadiazoles and 1,2,4-Triazoles with Aryl Iodides

(2009) Tsuyoshi Kawano et al.   ORGANIC LETTERS

Palladium-Catalyzed Direct Arylations of 1,2,3-Triazoles with Aryl Chlorides using Conventional Heating

(2008) Lutz Ackermann et al.   ADVANCED SYNTHESIS & CATALYSIS

Cu-Catalyzed Azide−Alkyne Cycloaddition

(2008) Morten Meldal et al.   CHEMICAL REVIEWS

Assisted Ruthenium-Catalyzed C−H Bond Activation: Carboxylic Acids as Cocatalysts for Generally Applicable Direct Arylations in Apolar Solvents

(2008) Lutz Ackermann et al.   ORGANIC LETTERS

γ-Valerolactone—a sustainable liquid for energy and carbon-based chemicals

(2007) István T. Horváth et al.   GREEN CHEMISTRY