Copper-catalysed azide–alkyne cycloadditions (CuAAC): an update

Fine-Tunable Tris(triazolyl)methane Ligands for Copper(I)- Catalyzed Azide-Alkyne Cycloaddition Reactions

(2014) Erhan Ozkal et al.   ADVANCED SYNTHESIS & CATALYSIS

Copper-Chelating Azides for Efficient Click Conjugation Reactions in Complex Media

(2014) Valentina Bevilacqua et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

High-Density Functionalization and Cross-Linking of DNA: “Click” and “Bis-Click” Cycloadditions Performed on Alkynylated Oligonucleotides with Fluorogenic Anthracene Azides

(2014) Suresh S. Pujari et al.   BIOCONJUGATE CHEMISTRY

Monitoring Dynamic Glycosylation in Vivo Using Supersensitive Click Chemistry

(2014) Hao Jiang et al.   BIOCONJUGATE CHEMISTRY

1,2,3-Triazoles from carbonyl azides and alkynes: filling the gap

(2014) Estela Haldón et al.   CHEMICAL COMMUNICATIONS

Transition metal-mediated bioorthogonal protein chemistry in living cells

(2014) Maiyun Yang et al.   CHEMICAL SOCIETY REVIEWS

An Efficient Photocatalyst for the Azide–Alkyne Click Reaction Based on Direct Photolysis of a Copper(II)/Carboxylate Complex

(2014) Xin Guan et al.   CHEMISTRY LETTERS

Reaction of Alkynes and Azides: Not Triazoles Through Copper-Acetylides but Oxazoles Through Copper-Nitrene Intermediates

(2014) Estela Haldón et al.   CHEMISTRY-A EUROPEAN JOURNAL

Sunlight-Driven Copper-Catalyst Activation Applied to Photolatent Click Chemistry

(2014) Rédouane Beniazza et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Highly Active and Magnetically Recoverable Tris(triazolyl)-CuICatalyst for Alkyne-Azide Cycloaddition Reactions

(2014) Dong Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Copper Immobilized on Nanosilica Triazine Dendrimer (Cu(II)-TD@nSiO2)-Catalyzed Regioselective Synthesis of 1,4-Disubstituted 1,2,3-Triazoles and Bis- and Tris-Triazoles via a One-Pot Multicomponent Click Reaction

(2014) Mahboobeh Nasr-Esfahani et al.   JOURNAL OF ORGANIC CHEMISTRY

Polymer-Assisted Chain-like Organization of CuNi Alloy Nanoparticles: Solvent-Adoptable Pseudohomogeneous Catalysts for Alkyne–Azide Click Reactions with Magnetic Recyclability

(2014) Mrinmoy Biswas et al.   Journal of Physical Chemistry C

Polymer end group modifications and polymer conjugations via “click” chemistry employing microreactor technology

(2014) Joke Vandenbergh et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Recyclable Catalytic Dendrimer Nanoreactor for Part-Per-Million CuI Catalysis of “Click” Chemistry in Water

(2014) Christophe Deraedt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recoverable Cu/SiO2 composite-catalysed click synthesis of 1,2,3-triazoles in water media

(2014) Cátia Schwartz Radatz et al.   NEW JOURNAL OF CHEMISTRY

Reduction of Cu(II) by photochemically generated phosphonyl radicals to generate Cu(I) as catalyst for atom transfer radical polymerization and azide-alkyne cycloaddition click reactions

(2014) Yusuf Yagci et al.   POLYMER

Application of CuAAC for the covalent immobilization of homogeneous catalysts

(2014) Antony E. Fernandes et al.   TETRAHEDRON

Biocompatible click chemistry enabled compartment-specific pH measurement inside E. coli

(2014) Maiyun Yang et al.   Nature Communications

Copper nanoparticle heterogeneous catalytic ‘click’ cycloaddition confirmed by single-molecule spectroscopy

(2014) Matthew R. Decan et al.   Nature Communications

Catalytic and Computational Studies of N-Heterocyclic Carbene or Phosphine-Containing Copper(I) Complexes for the Synthesis of 5-Iodo-1,2,3-Triazoles

(2014) Steven Lal et al.   ACS Catalysis

Multicomponent azide–alkyne cycloaddition catalyzed by impregnated bimetallic nickel and copper on magnetite

(2014) Juana M. Pérez et al.   RSC Advances

Supported CuBr on graphene oxide/Fe3O4: a highly efficient, magnetically separable catalyst for the multi-gram scale synthesis of 1,2,3-triazoles

(2014) Xingquan Xiong et al.   RSC Advances

Continuous-flow azide–alkyne cycloadditions with an effective bimetallic catalyst and a simple scavenger system

(2014) Sándor B. Ötvös et al.   RSC Advances

Eco-Efficient, Green, and Scalable Synthesis of 1,2,3-Triazoles Catalyzed by Cu(I) Catalyst on Waste Oyster Shell Powders

(2014) Xingquan Xiong et al.   ACS Sustainable Chemistry & Engineering

Photopolymerization Reactions Using the Photoinitiated Copper (I)-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) Reaction

(2013) Tao Gong et al.   ADVANCED MATERIALS

An Abnormal N-Heterocyclic Carbene-Copper(I) Complex in Click Chemistry

(2013) Samaresh Chandra Sau et al.   ADVANCED SYNTHESIS & CATALYSIS

Light-Induced Click Reactions

(2013) Mehmet Atilla Tasdelen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An efficient synthesis of 3-triazolyl-2(1H)-quinolones by CuTC-catalyzed azide-alkyne cycloaddition reaction

(2013) Samir Messaoudi et al.   APPLIED ORGANOMETALLIC CHEMISTRY

Advancements in the mechanistic understanding of the copper-catalyzed azide–alkyne cycloaddition

(2013) Regina Berg et al.   Beilstein Journal of Organic Chemistry

Efficient continuous-flow synthesis of novel 1,2,3-triazole-substituted β-aminocyclohexanecarboxylic acid derivatives with gram-scale production

(2013) Sándor B Ötvös et al.   Beilstein Journal of Organic Chemistry

Copper-Assisted Click Reactions for Activity-Based Proteomics: Fine-Tuned Ligands and Refined Conditions Extend the Scope of Application

(2013) Georg C. Rudolf et al.   CHEMBIOCHEM

Reusable and highly active supported copper(i)–NHC catalysts for Click chemistry

(2013) John-Michael Collinson et al.   CHEMICAL COMMUNICATIONS

“Click” dendrimers as efficient nanoreactors in aqueous solvent: Pd nanoparticle stabilization for sub-ppm Pd catalysis of Suzuki–Miyaura reactions of aryl bromides

(2013) Christophe Deraedt et al.   CHEMICAL COMMUNICATIONS

Click Chemistry for Drug Development and Diverse Chemical–Biology Applications

(2013) Prakasam Thirumurugan et al.   CHEMICAL REVIEWS

A Photoreducible Copper(II)-Tren Complex of Practical Value: Generation of a Highly Reactive Click Catalyst

(2013) Lydie Harmand et al.   CHEMISTRY-A EUROPEAN JOURNAL

Click To Bind: Metal Sensors

(2013) Jonathan J. Bryant et al.   Chemistry-An Asian Journal

Recyclable Porous Polymer-Supported Copper Catalysts for Glaser and Huisgen 1,3-Diolar Cycloaddition Reactions

(2013) Qi Sun et al.   Chemistry-An Asian Journal

Alkyne-Azide Cycloadditions with Copper Powder in a High-Pressure Continuous-Flow Reactor: High-Temperature Conditions versus the Role of Additives

(2013) Sándor B. Ötvös et al.   Chemistry-An Asian Journal

Stoichiometric sensitivity and structural diversity in click-active copper(i) N,S-heterocyclic carbene complexes

(2013) Xiaoyan Han et al.   DALTON TRANSACTIONS

Recent developments in polymer–block–polypeptide and protein–polymer bioconjugate hybrid materials

(2013) Renjith P. Johnson et al.   EUROPEAN POLYMER JOURNAL

Copper on chitosan: a recyclable heterogeneous catalyst for azide–alkyne cycloaddition reactions in water

(2013) R. B. Nasir Baig et al.   GREEN CHEMISTRY

Polymer anchored Cu(ii) complex: an efficient and recyclable catalytic system for the one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles starting from anilines in water

(2013) Susmita Roy et al.   GREEN CHEMISTRY

Scratching the catalytic surface of mechanochemistry: a multi-component CuAAC reaction using a copper reaction vial

(2013) Teresa L. Cook et al.   GREEN CHEMISTRY

Parallel Stranded DNA Stabilized with Internal Sugar Cross-Links: Synthesis and Click Ligation of Oligonucleotides Containing 2′-Propargylated Isoguanosine

(2013) Suresh S. Pujari et al.   JOURNAL OF ORGANIC CHEMISTRY

Stepwise Click Functionalization of DNA through a Bifunctional Azide with a Chelating and a Nonchelating Azido Group

(2013) Sachin A. Ingale et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-Granule-Catalyzed Microwave-Assisted Click Synthesis of Polyphenol Dendrimers

(2013) Choon Young Lee et al.   JOURNAL OF ORGANIC CHEMISTRY

Alkenes as Azido Precursors for the One-Pot Synthesis of 1,2,3-Triazoles Catalyzed by Copper Nanoparticles on Activated Carbon

(2013) Francisco Alonso et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Copper(I)-Catalyzed Azide–Alkyne Cycloaddition to Quaternary Oxindoles

(2013) Feng Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Well-Defined Diimine Copper(I) Complexes as Catalysts in Click Azide-Alkyne Cycloaddition Reactions

(2013) Jordi Barta et al.   MOLECULES

Site-specific protein labeling using PRIME and chelation-assisted click chemistry

(2013) Chayasith Uttamapinant et al.   Nature Protocols

Porous copper catalyzed click reaction in water

(2013) Chen Zhang et al.   NEW JOURNAL OF CHEMISTRY

Evaluation and development of novel photoinitiator complexes for photoinitiating the copper-catalyzed azide–alkyne cycloaddition reaction

(2013) Abeer A. Alzahrani et al.   Polymer Chemistry

Direct Evidence of a Dinuclear Copper Intermediate in Cu(I)-Catalyzed Azide-Alkyne Cycloadditions

(2013) B. T. Worrell et al.   SCIENCE

Synthesis of monodisperse Cu nanoparticles in Ionic Liquids: A synthetic and catalytic approach of in situ nanoparticles

(2013) Balaji Mohan et al.   SOLID STATE SCIENCES

Application of magnetic nanoparticle-supported CuBr: a highly efficient and reusable catalyst for the one-pot and scale-up synthesis of 1,2,3-triazoles under microwave-assisted conditions

(2013) Xingquan Xiong et al.   Catalysis Science & Technology

Recent advances in the Cu(i)-catalyzed azide–alkyne cycloaddition: focus on functionally substituted azides and alkynes

(2013) Nadezhda V. Sokolova et al.   RSC Advances

Flow Chemistry - A Key Enabling Technology for (Multistep) Organic Synthesis

(2012) Jens Wegner et al.   ADVANCED SYNTHESIS & CATALYSIS

Highly Active Dinuclear Copper Catalysts for Homogeneous Azide-Alkyne Cycloadditions

(2012) Regina Berg et al.   ADVANCED SYNTHESIS & CATALYSIS

Click Functionalization of Gold Nanoparticles Using the Very Efficient Catalyst Copper(I) (Hexabenzyl)tris(2-aminoethyl)- amine Bromide

(2012) Pengxiang Zhao et al.   ADVANCED SYNTHESIS & CATALYSIS

Fast, Cell-Compatible Click Chemistry with Copper-Chelating Azides for Biomolecular Labeling

(2012) Chayasith Uttamapinant et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper Catalyst Activation Driven by Photoinduced Electron Transfer: A Prototype Photolatent Click Catalyst

(2012) Lydie Harmand et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A versatile solvent-free azide–alkyne click reaction catalyzed by in situ generated copper nanoparticles

(2012) Atchutarao Pathigoolla et al.   APPLIED CATALYSIS A-GENERAL

Photoinitiated Alkyne–Azide Click and Radical Cross-Linking Reactions for the Patterning of PEG Hydrogels

(2012) Rodney T. Chen et al.   BIOMACROMOLECULES

Optimization of acetonitrile co-solvent and copper stoichiometry for pseudo-ligandless click chemistry with nucleic acids

(2012) Eduardo Paredes et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Multicomponent Synthesis of 1,2,3-Triazoles in Water Catalyzed by Silica-Immobilized NHC–Cu(I)

(2012) Li Wan et al.   CATALYSIS LETTERS

Click Chemistry of Alkyne-Azide Cycloaddition using Nanostructured Copper Catalysts

(2012) Tienan Jin et al.   ChemCatChem

A water soluble CuI–NHC for CuAAC ligation of unprotected peptides under open air conditions

(2012) Christelle Gaulier et al.   CHEMICAL COMMUNICATIONS

ZnO–CuO core–branch nanocatalysts for ultrasound-assisted azide–alkyne cycloaddition reactions

(2012) Ji Chan Park et al.   CHEMICAL COMMUNICATIONS

Click chemistry in carbon nanoreactors

(2012) Graham A. Rance et al.   CHEMICAL COMMUNICATIONS

Copper(I)-Catalyzed Azide-Alkyne Cycloadditions in Microflow: Catalyst Activity, High-T Operation, and an Integrated Continuous Copper Scavenging Unit

(2012) Alvaro Carlos Varas et al.   ChemSusChem

Synthesis and structural characterisation of (aryl-BIAN)copper(i) complexes and their application as catalysts for the cycloaddition of azides and alkynes

(2012) Lidong Li et al.   DALTON TRANSACTIONS

(Iminophosphorane)copper(I) Complexes as Highly Efficient Catalysts for 1,3-Dipolar Cycloaddition of Azides with Terminal and 1-Iodoalkynes in Water: One-Pot Multi-Component Reaction from Alkynes and in situ Generated Azides

(2012) Joaquín García-Álvarez et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

A highly active magnetically recoverable nano ferrite-glutathione-copper (nano-FGT-Cu) catalyst for Huisgen 1,3-dipolar cycloadditions

(2012) R. B. Nasir Baig et al.   GREEN CHEMISTRY

Copper nanoparticulates in Guar-gum: a recyclable catalytic system for the Huisgen [3 + 2]-cycloaddition of azides and alkynes without additives under ambient conditions

(2012) Ajeet Kumar et al.   GREEN CHEMISTRY

Magnetic copper–iron nanoparticles as simple heterogeneous catalysts for the azide–alkyne click reaction in water

(2012) Reuben Hudson et al.   GREEN CHEMISTRY

Amphiphilic Self-Assembled Polymeric Copper Catalyst to Parts per Million Levels: Click Chemistry

(2012) Yoichi M. A. Yamada et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Azide-Alkyne Huisgen [3+2] Cycloaddition Using CuO Nanoparticles

(2012) Hyunje Woo et al.   MOLECULES

Chemoselective Sequential “Click” Ligation Using Unsymmetrical Bisazides

(2012) Zhao Yuan et al.   ORGANIC LETTERS

Heteroleptic Bis(N-heterocyclic carbene)Copper(I) Complexes: Highly Efficient Systems for the [3+2] Cycloaddition of Azides and Alkynes

(2012) Faïma Lazreg et al.   ORGANOMETALLICS

Click Chemistry with Polymers, Dendrimers, and Hydrogels for Drug Delivery

(2012) Enrique Lallana et al.   PHARMACEUTICAL RESEARCH

Recyclable clay supported Cu (II) catalyzed tandem one-pot synthesis of 1-aryl-1,2,3-triazoles

(2012) Shabber Mohammed et al.   TETRAHEDRON

Magnetically separable CuFe2O4 nano particles catalyzed multicomponent synthesis of 1,4-disubstituted 1,2,3-triazoles in tap water using ‘click chemistry’

(2012) B.S.P. Anil Kumar et al.   TETRAHEDRON LETTERS

Resin-Supported Catalysts for CuAAC Click Reactions in Aqueous or Organic Solvents

(2012) Stanislav I. Presolski et al.   ACS Combinatorial Science

Synthesis of Vasorelaxaing 1,4-Disubstituted 1,2,3-Triazoles Catalyzed by a 4′-Phenyl-2,2′:6′,2′′-Terpyridine Copper(II) Complex Immobilized on Activated Multiwalled Carbon Nanotubes

(2012) Hashem Sharghi et al.   Asian Journal of Organic Chemistry

Click Dendrimers and Triazole-Related Aspects: Catalysts, Mechanism, Synthesis, and Functions. A Bridge between Dendritic Architectures and Nanomaterials

(2011) Didier Astruc et al.   ACCOUNTS OF CHEMICAL RESEARCH

The Efficient Copper(I) (Hexabenzyl)tren Catalyst and Dendritic Analogues for Green “Click” Reactions between Azides and Alkynes in Organic Solvent and in Water: Positive Dendritic Effects and Monometallic Mechanism

(2011) Liyuan Liang et al.   ADVANCED SYNTHESIS & CATALYSIS

Nanoporous Copper Metal Catalyst in Click Chemistry: Nanoporosity-Dependent Activity without Supports and Bases

(2011) Tienan Jin et al.   ADVANCED SYNTHESIS & CATALYSIS

Reliable and Efficient Procedures for the Conjugation of Biomolecules through Huisgen Azide-Alkyne Cycloadditions

(2011) Enrique Lallana et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Increasing the Efficacy of Bioorthogonal Click Reactions for Bioconjugation: A Comparative Study

(2011) Christen Besanceney-Webler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Deciding Whether To Go with the Flow: Evaluating the Merits of Flow Reactors for Synthesis

(2011) Ryan L. Hartman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multistep flow synthesis of vinyl azides and their use in the copper-catalyzed Huisgen-type cycloaddition under inductive-heating conditions

(2011) Lukas Kupracz et al.   Beilstein Journal of Organic Chemistry

Regenerative Biomaterials that “Click”: Simple, Aqueous-Based Protocols for Hydrogel Synthesis, Surface Immobilization, and 3D Patterning

(2011) Chelsea M. Nimmo et al.   BIOCONJUGATE CHEMISTRY

“Clicking” on/with polymers: a rapidly expanding field for the straightforward preparation of novel macromolecular architectures

(2011) Kristian Kempe et al.   CHEMICAL SOCIETY REVIEWS

Fabrication and Functionalization of Hydrogels through “Click” Chemistry

(2011) Sezin Yigit et al.   Chemistry-An Asian Journal

10 Years of Click Chemistry: Synthesis and Applications of Ferrocene-Derived Triazoles

(2011) Venkataraman Ganesh et al.   Chemistry-An Asian Journal

Ligand-Assisted, Copper(II) Acetate-Accelerated Azide-Alkyne Cycloaddition

(2011) Heather A. Michaels et al.   Chemistry-An Asian Journal

Sulfonyl and Phosphoryl Azides: Going Further Beyond the Click Realm of Alkyl and Aryl Azides

(2011) Seok Hwan Kim et al.   Chemistry-An Asian Journal

Sulfated Ligands for the Copper(I)-Catalyzed Azide-Alkyne Cycloaddition

(2011) Wei Wang et al.   Chemistry-An Asian Journal

Click Chemistry: 1,2,3-Triazoles as Pharmacophores

(2011) Sandip G. Agalave et al.   Chemistry-An Asian Journal

Copper Nanoparticle-Catalyzed CarbonCarbon and CarbonHeteroatom Bond Formation with a Greener Perspective

(2011) Brindaban C. Ranu et al.   ChemSusChem

The copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC) “click” reaction and its applications. An overview

(2011) Liyuan Liang et al.   COORDINATION CHEMISTRY REVIEWS

The Use of Ligands in Copper-Catalyzed [3+2] Azide-Alkyne Cycloaddition: Clicker than Click Chemistry?

(2011) Silvia Diez-Gonzalez   CURRENT ORGANIC CHEMISTRY

Copper(I) Complexes of Normal and Abnormal Carbenes and Their Use as Catalysts for the Huisgen [3+2] Cycloaddition between Azides and Alkynes

(2011) Stephan Hohloch et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

The combination of living radical polymerization and click chemistry for the synthesis of advanced macromolecular architectures

(2011) Niels Akeroyd et al.   EUROPEAN POLYMER JOURNAL

Reusable ammonium salt-tagged NHC–Cu(i) complexes: preparation and catalytic application in the three component click reaction

(2011) Wenlong Wang et al.   GREEN CHEMISTRY

Stabilization of Cu(0)-nanoparticles into the nanopores of modified montmorillonite: An implication on the catalytic approach for “Click” reaction between azides and terminal alkynes

(2011) Bibek Jyoti Borah et al.   GREEN CHEMISTRY

Cu2O acting as a robust catalyst in CuAAC reactions: water is the required medium

(2011) Kai Wang et al.   GREEN CHEMISTRY

[CuBr(PPh3)3] for Azide−Alkyne Cycloaddition Reactions under Strict Click Conditions

(2011) Steven Lal et al.   JOURNAL OF ORGANIC CHEMISTRY

Acid–Base Jointly Promoted Copper(I)-Catalyzed Azide–Alkyne Cycloaddition

(2011) Changwei Shao et al.   JOURNAL OF ORGANIC CHEMISTRY

Multicomponent Click Synthesis of 1,2,3-Triazoles from Epoxides in Water Catalyzed by Copper Nanoparticles on Activated Carbon

(2011) Francisco Alonso et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly active, thermo-responsive polymeric catalytic system for reuse in aqueous and organic CuAAC reactions

(2011) Sofie Wallyn et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Cellular Consequences of Copper Complexes Used To Catalyze Bioorthogonal Click Reactions

(2011) David C. Kennedy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Experimental Investigation on the Mechanism of Chelation-Assisted, Copper(II) Acetate-Accelerated Azide–Alkyne Cycloaddition

(2011) Gui-Chao Kuang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photoinduced Free Radical Promoted Copper(I)-Catalyzed Click Chemistry for Macromolecular Syntheses

(2011) Mehmet Atilla Tasdelen et al.   MACROMOLECULES

Spatial and temporal control of the alkyne–azide cycloaddition by photoinitiated Cu(II) reduction

(2011) Brian J. Adzima et al.   Nature Chemistry

Comparison of diffusion coefficients for matched pairs of macrocyclic and linear molecules over a drug-like molecular weight range

(2011) Andrew R. Bogdan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Click chemistry from organic halides, diazonium salts and anilines in water catalysed by copper nanoparticles on activated carbon

(2011) Francisco Alonso et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Quick and highly efficient copper-catalyzed cycloaddition of organic azides with terminal alkynes

(2011) Dong Wang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and Reactivity of Sulfamoyl Azides and 1-Sulfamoyl-1,2,3-triazoles

(2011) Jeffrey C. Culhane et al.   ORGANIC LETTERS

Synthesis of 5-Iodo-1,2,3-triazole-Containing Macrocycles Using Copper Flow Reactor Technology

(2011) Andrew R. Bogdan et al.   ORGANIC LETTERS

A Copper(I) Isonitrile Complex as a Heterogeneous Catalyst for Azide−Alkyne Cycloaddition in Water

(2011) Meina Liu et al.   ORGANIC LETTERS

Novel Phosphinite and Phosphonite Copper(I) Complexes: Efficient Catalysts for Click Azide–Alkyne Cycloaddition Reactions

(2011) Steven Lal et al.   ORGANOMETALLICS

Click Chemistry for Drug Delivery Nanosystems

(2011) Enrique Lallana et al.   PHARMACEUTICAL RESEARCH

Hydroxyapatite-supported copper(II)-catalyzed azide–alkyne [3+2] cycloaddition with neither reducing agents nor bases in water

(2011) Yoshiro Masuyama et al.   TETRAHEDRON LETTERS

Heterogeneous azide–alkyne click chemistry: towards metal-free end products

(2011) Bart Dervaux et al.   Chemical Science

Well-defined copper(i) complexes for Click azide–alkyne cycloaddition reactions: one Click beyond

(2011) Silvia Díez-González   Catalysis Science & Technology

Covalently immobilized tris(triazolyl)methanol–Cu(i) complexes: highly active and recyclable catalysts for CuAAC reactions

(2011) Erhan Ozkal et al.   Catalysis Science & Technology

Polymer-Supported 1,5,7-Triazabicyclo[4.4.0]dec-5-ene as Polyvalent Ligands in the Copper-Catalyzed Huisgen 1,3-Dipolar Cycloaddition

(2010) Alberto Coelho et al.   ADVANCED SYNTHESIS & CATALYSIS

Copper(I) Acetate: A Structurally Simple but Highly Efficient Dinuclear Catalyst for Copper-Catalyzed Azide-Alkyne Cycloaddition

(2010) Changwei Shao et al.   ADVANCED SYNTHESIS & CATALYSIS

Non-Magnetic and Magnetic Supported Copper(I) Chelating Adsorbents as Efficient Heterogeneous Catalysts and Copper Scavengers for Click Chemistry

(2010) Alicia Megia-Fernandez et al.   ADVANCED SYNTHESIS & CATALYSIS

Mechanistic Insights into Copper(I)-Catalyzed Azide-Alkyne Cycloadditions using Continuous Flow Conditions

(2010) Michael Fuchs et al.   ADVANCED SYNTHESIS & CATALYSIS

Multicomponent Synthesis of 1,2,3-Triazoles in Water Catalyzed by Copper Nanoparticles on Activated Carbon

(2010) Francisco Alonso et al.   ADVANCED SYNTHESIS & CATALYSIS

Azide−Alkyne “Click” Conjugation of 8-Aza-7-deazaadenine-DNA: Synthesis, Duplex Stability, and Fluorogenic Dye Labeling

(2010) Frank Seela et al.   BIOCONJUGATE CHEMISTRY

Labeling Live Cells by Copper-Catalyzed Alkyne−Azide Click Chemistry

(2010) Vu Hong et al.   BIOCONJUGATE CHEMISTRY

Click Chemistry for Rapid Labeling and Ligation of RNA

(2010) Eduardo Paredes et al.   CHEMBIOCHEM

Polymeric ligands as homogeneous, reusable catalyst systems for copper assisted click chemistry

(2010) Mieke Lammens et al.   CHEMICAL COMMUNICATIONS

Copper nitride nanoparticles supported on a superparamagnetic mesoporous microsphere for toxic-free click chemistry

(2010) Byoung Se Lee et al.   CHEMICAL COMMUNICATIONS

In situ click chemistry: probing the binding landscapes of biological molecules

(2010) Sreeman K. Mamidyala et al.   CHEMICAL SOCIETY REVIEWS

Copper-catalyzed azide–alkyne cycloaddition (CuAAC) and beyond: new reactivity of copper(i) acetylides

(2010) Jason E. Hein et al.   CHEMICAL SOCIETY REVIEWS

Click chemistry with DNA

(2010) Afaf H. El-Sagheer et al.   CHEMICAL SOCIETY REVIEWS

Efficient Access to New Chemical Space Through Flow-Construction of Druglike Macrocycles Through Copper-Surface-Catalyzed Azide-Alkyne Cycloaddition Reactions

(2010) Andrew R. Bogdan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Green and Sustainable Chemical Synthesis Using Flow Microreactors

(2010) Jun-ichi Yoshida et al.   ChemSusChem

[(NHC)CuX] complexes: Synthesis, characterization and catalytic activities in reduction reactions and Click Chemistry. On the advantage of using well-defined catalytic systems

(2010) Silvia Díez-González et al.   DALTON TRANSACTIONS

Unsupported Copper Nanoparticles in the 1,3-Dipolar Cycloaddition of Terminal Alkynes and Azides

(2010) Francisco Alonso et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Aromatic Nitrogen Donors for Efficient Copper(I)-NHC CuAAC under Reductant-Free Conditions

(2010) Marie-Laure Teyssot et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A highly efficient copper(i) catalyst for the 1,3-dipolar cycloaddition of azides with terminal and 1-iodoalkynes in water: regioselective synthesis of 1,4-disubstituted and 1,4,5-trisubstituted 1,2,3-triazoles

(2010) Joaquín García-Álvarez et al.   GREEN CHEMISTRY

Solvent-free synthesis of 1,4-disubstituted 1,2,3-triazoles using a low amount of Cu(PPh3)2NO3 complex

(2010) Dong Wang et al.   GREEN CHEMISTRY

Bridging homogeneous and heterogeneous catalysis with MOFs: “Click” reactions with Cu-MOF catalysts

(2010) I. Luz et al.   JOURNAL OF CATALYSIS

In situ cross-linked chitosan Cu(I) or Pd(II) complexes as a versatile, eco-friendly recyclable solid catalyst

(2010) Katia Martina et al.   JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL

Immobilized CuO Hollow Nanospheres Catalyzed Alkyne-Azide Cycloadditions

(2010) Hyuntae Kang et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Cross-Linked DNA Generated by “Bis-click” Reactions with Bis-functional Azides: Site Independent Ligation of Oligonucleotides via Nucleobase Alkynyl Chains

(2010) Suresh S. Pujari et al.   JOURNAL OF ORGANIC CHEMISTRY

Carboxylic Acid-Promoted Copper(I)-Catalyzed Azide−Alkyne Cycloaddition

(2010) Changwei Shao et al.   JOURNAL OF ORGANIC CHEMISTRY

Chelation-Assisted, Copper(II)-Acetate-Accelerated Azide−Alkyne Cycloaddition

(2010) Gui-Chao Kuang et al.   JOURNAL OF ORGANIC CHEMISTRY

Rapid synthesis of block and cyclic copolymers via click chemistry in the presence of copper nanoparticles

(2010) Eric D. Pressly et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Chemoselective Attachment of Small Molecule Effector Functionality to Human Adenoviruses Facilitates Gene Delivery to Cancer Cells

(2010) Partha Sarathi Banerjee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tailored Ligand Acceleration of the Cu-Catalyzed Azide−Alkyne Cycloaddition Reaction: Practical and Mechanistic Implications

(2010) Stanislav I. Presolski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biocompatible Copper(I) Catalysts for in Vivo Imaging of Glycans

(2010) David Soriano del Amo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regioselective Formation of 2,5-Disubstituted Oxazoles Via Copper(I)-Catalyzed Cycloaddition of Acyl Azides and 1-Alkynes

(2010) Israel Cano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Alkyne–azide click reaction catalyzed by metallic copper under ultrasound

(2010) Pedro Cintas et al.   Nature Protocols

Efficient Synthesis of 1-Sulfonyl-1,2,3-triazoles

(2010) Jessica Raushel et al.   ORGANIC LETTERS

Polymeric nanomaterials from combined click chemistry and controlled radical polymerization

(2010) Rong Fu et al.   Polymer Chemistry

Light-induced copper(I)-catalyzed click chemistry

(2010) Mehmet Atilla Tasdelen et al.   TETRAHEDRON LETTERS

Zeo-click synthesis: CuI-zeolite-catalyzed one-pot two-step synthesis of triazoles from halides and related compounds

(2010) Valérie Bénéteau et al.   TETRAHEDRON LETTERS

Solvent-Free Microwave Promoted [3 + 2] Cycloaddition of Alkyne-Azide in Uniform CuO Hollow Nanospheres

(2010) Hyuntae Kang et al.   TOPICS IN CATALYSIS

Copper-in-Charcoal-Catalyzed, Tandem One-Pot Diazo Transfer-Click Reactions

(2009) Ching-Tien Lee et al.   ADVANCED SYNTHESIS & CATALYSIS

The Use of Copper Flow Reactor Technology for the Continuous Synthesis of 1,4-Disubstituted 1,2,3-Triazoles

(2009) Andrew R. Bogdan et al.   ADVANCED SYNTHESIS & CATALYSIS

Copper Nanoparticles on Charcoal for Multicomponent Catalytic Synthesis of 1,2,3-Triazole Derivatives from Benzyl Halides or Alkyl Halides, Terminal Alkynes and Sodium Azide in Water as a “Green” Solvent

(2009) Hashem Sharghi et al.   ADVANCED SYNTHESIS & CATALYSIS

Copper(I)-Catalyzed Cycloaddition of Organic Azides and 1-Iodoalkynes

(2009) Jason E. Hein et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multistep Synthesis Using Modular Flow Reactors: Bestmann-Ohira Reagent for the Formation of Alkynes and Triazoles

(2009) Ian R. Baxendale et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Functionalized Chitosan as a Green, Recyclable, Biopolymer-Supported Catalyst for the [3+2] Huisgen Cycloaddition

(2009) Mélanie Chtchigrovsky et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Analysis and Optimization of Copper-Catalyzed Azide–Alkyne Cycloaddition for Bioconjugation

(2009) Vu Hong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper nanoparticles in ionic liquids: Recyclable and efficient catalytic system for 1,3-dipolar cycloaddition reaction

(2009) Dilip Raut et al.   CATALYSIS COMMUNICATIONS

CuO hollow nanostructures catalyze [3 + 2] cycloaddition of azides with terminal alkynes

(2009) Jee Young Kim et al.   CHEMICAL COMMUNICATIONS

Risks of Copper and Iron Toxicity during Aging in Humans

(2009) George J. Brewer   CHEMICAL RESEARCH IN TOXICOLOGY

The application of CuAAC ‘click’ chemistry to catenane and rotaxane synthesis

(2009) Kevin D. Hänni et al.   CHEMICAL SOCIETY REVIEWS

Marrying click chemistry with polymerization: expanding the scope of polymeric materials

(2009) Patricia L. Golas et al.   CHEMICAL SOCIETY REVIEWS

Click chemistry under non-classical reaction conditions

(2009) C. Oliver Kappe et al.   CHEMICAL SOCIETY REVIEWS

Fluorogenic click reaction

(2009) Céline Le Droumaguet et al.   CHEMICAL SOCIETY REVIEWS

Improved Copper(I)-NHC Catalytic Efficiency on Huisgen Reaction by Addition of Aromatic Nitrogen Donors

(2009) Marie-Laure Teyssot et al.   CHEMISTRY-A EUROPEAN JOURNAL

CuII-Hydrotalcite as an Efficient Heterogeneous Catalyst for Huisgen [3+2] Cycloaddition

(2009) Kayambu Namitharan et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Supported Copper Hydroxide on Titanium Oxide as an Efficient Reusable Heterogeneous Catalyst for 1,3-Dipolar Cycloaddition of Organic Azides to Terminal Alkynes

(2009) Kazuya Yamaguchi et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Supported Copper Hydroxide as an Efficient, Ligand-free, and Heterogeneous Precatalyst for 1,3-Dipolar Cycloadditions of Organic Azides to Terminal Alkynes

(2009) Tatsuyori Katayama et al.   ChemSusChem

Highly active copper-catalysts for azide-alkynecycloaddition

(2009) Zsombor Gonda et al.   DALTON TRANSACTIONS

An Efficient (2-Aminoarenethiolato)copper(I) Complex for the Copper-Catalysed Huisgen Reaction (CuAAC)

(2009) Pierangelo Fabbrizzi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Structures of Copper Complexes of the Hybrid [SNS] Ligand of Bis(2-(benzylthio)ethyl)amine and Facile Catalytic Formation of 1-Benzyl-4-phenyl-1H-1,2,3-triazole through Click Reaction

(2009) Shi-Qiang Bai et al.   INORGANIC CHEMISTRY

Ultrasound-Promoted Copper-Catalyzed Azide−Alkyne Cycloaddition

(2009) Giancarlo Cravotto et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Heterogeneous Catalysis of a Copper-Coated Atomic Force Microscopy Tip for Direct-Write Click Chemistry

(2009) Walter F. Paxton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

“Flash” Solvent-free Synthesis of Triazoles Using a Supported Catalyst

(2009) Ibtissem Jlalia et al.   MOLECULES

Preorganized macromolecular gene delivery systems: amphiphilic β-cyclodextrin “click clusters”

(2009) Alejandro Méndez-Ardoy et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Copper(i) complexes as catalysts for the synthesis of N-sulfonyl-1,2,3-triazoles from N-sulfonylazides and alkynes

(2009) Israel Cano et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Apparent Copper(II)-Accelerated Azide−Alkyne Cycloaddition

(2009) Wendy S. Brotherton et al.   ORGANIC LETTERS

A Highly Active Catalyst for Huisgen 1,3-Dipolar Cycloadditions Based on the Tris(triazolyl)methanol−Cu(I) Structure

(2009) Salih Özçubukçu et al.   ORGANIC LETTERS

Copper nanoparticles in click chemistry: an alternative catalytic system for the cycloaddition of terminal alkynes and azides

(2009) Francisco Alonso et al.   TETRAHEDRON LETTERS

Efficient construction of therapeutics, bioconjugates, biomaterials and bioactive surfaces using azide–alkyne “click” chemistry☆

(2008) J LUTZ et al.   ADVANCED DRUG DELIVERY REVIEWS

Copper-Catalyzed Cycloaddition of Sulfonyl Azides with Alkynes to SynthesizeN-Sulfonyltriazoles ‘on Water’ at Room Temperature

(2008) Feng Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

[(NHC)2Cu]X Complexes as Efficient Catalysts for Azide-Alkyne Click Chemistry at Low Catalyst Loadings

(2008) Silvia Díez-González et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

‘Click’ cycloaddition catalysts: copper(i) and copper(ii) tris(triazolylmethyl)amine complexes

(2008) Paul S. Donnelly et al.   CHEMICAL COMMUNICATIONS

A highly active and reusable copper(i)-tren catalyst for the “click” 1,3-dipolar cycloaddition of azides and alkynes

(2008) Nicolas Candelon et al.   CHEMICAL COMMUNICATIONS

A [(NHC)CuCl] complex as a latent Click catalyst

(2008) Silvia Díez-González et al.   CHEMICAL COMMUNICATIONS

Cu-Catalyzed Azide−Alkyne Cycloaddition

(2008) Morten Meldal et al.   CHEMICAL REVIEWS

Fast Access to RobustC-Sialoside Multimers

(2008) Caroline Papin et al.   CHEMISTRY-A EUROPEAN JOURNAL

Click Chemistry and Medicinal Chemistry: A Case of “Cyclo-Addiction”

(2008) A. D. Moorhouse et al.   ChemMedChem

Copper-Zeolites as Catalysts for the Coupling of Terminal Alkynes: An Efficient Synthesis of Diynes

(2008) Philippe Kuhn et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Quick and highly efficient copper-catalyzed cycloaddition of aliphatic and aryl azides with terminal alkynes “on water”

(2008) Feng Wang et al.   GREEN CHEMISTRY

Histone Deacetylase Inhibitors through Click Chemistry

(2008) Jie Shen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Microwave-Enhanced Ionothermal CuAAC for the Synthesis of Glycoclusters on a Calix[4]arene Platform

(2008) Alessandra Vecchi et al.   JOURNAL OF ORGANIC CHEMISTRY

Validation of the Copper(I)-Catalyzed Azide−Alkyne Coupling in Ionic Liquids. Synthesis of a Triazole-LinkedC-Disaccharide as a Case Study

(2008) Alberto Marra et al.   JOURNAL OF ORGANIC CHEMISTRY

Mechanistic Studies on the Cu-Catalyzed Three-Component Reactions of Sulfonyl Azides, 1-Alkynes and Amines, Alcohols, or Water: Dichotomy via a Common Pathway

(2008) Eun Jeong Yoo et al.   JOURNAL OF ORGANIC CHEMISTRY

PVP-Stabilized Copper Nanoparticles:  A Reusable Catalyst for “Click” Reaction between Terminal Alkynes and Azides in Nonaqueous Solvents

(2008) A. Sarkar et al.   Journal of Physical Chemistry C

1,3-Dipolar Cycloaddition of Organic Azides to Alkynes by a Dicopper-Substituted Silicotungstate

(2008) Keigo Kamata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure–Reactivity Correlation in “Click” Chemistry: Substituent Effect on Azide Reactivity

(2008) Patricia L. Golas et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Polymer “Clicking” by CuAAC Reactions

(2008) Morten Meldal   MACROMOLECULAR RAPID COMMUNICATIONS

Construction of Linear Polymers, Dendrimers, Networks, and Other Polymeric Architectures by Copper‐Catalyzed Azide‐Alkyne Cycloaddition “Click” Chemistry

(2008) Jeremiah A. Johnson et al.   MACROMOLECULAR RAPID COMMUNICATIONS

‘Click’ Chemistry in Polymer and Material Science: An Update

(2008) Wolfgang H. Binder et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Facile Access to an Efficient Solid-Supported Click Catalyst System Based on Poly(ethyleneimine)

(2008) Lies Bonami et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Convergent Synthesis of Second Generation AB-Type Miktoarm Dendrimers Using “Click” Chemistry Catalyzed by Copper Wire

(2008) Carl N. Urbani et al.   MACROMOLECULES

Heterogeneous Copper Catalyst for the Cycloaddition of Azides and Alkynes without Additives under Ambient Conditions

(2008) In Soo Park et al.   ORGANIC LETTERS

Triazole-Linked Analogue of Deoxyribonucleic Acid (TLDNA): Design, Synthesis, and Double-Strand Formation with Natural DNA

(2008) Hiroyuki Isobe et al.   ORGANIC LETTERS

Click Chemistry, A Powerful Tool for Pharmaceutical Sciences

(2008) Christopher D. Hein et al.   PHARMACEUTICAL RESEARCH

SiO2–NHC–Cu(I): an efficient and reusable catalyst for [3+2] cycloaddition of organic azides and terminal alkynes under solvent-free reaction conditions at room temperature

(2008) Pinhua Li et al.   TETRAHEDRON

Copper(I)-doped Wyoming’s montmorillonite for the synthesis of disubstituted 1,2,3-triazoles

(2008) Ibtissem Jlalia et al.   TETRAHEDRON LETTERS

Modification of DNA with Octadiynyl Side Chains: Synthesis, Base Pairing, and Formation of Fluorescent Coumarin Dye Conjugates of Four Nucleobases by the Alkyne−Azide “Click” Reaction

(2007) Frank Seela et al.   BIOCONJUGATE CHEMISTRY

Click chemistry reactions in medicinal chemistry: Applications of the 1,3-dipolar cycloaddition between azides and alkynes

(2007) Gian Cesare Tron et al.   MEDICINAL RESEARCH REVIEWS