N-myc downstream-regulated gene 2 protects blood-brain barrier integrity following cerebral ischemia

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

ATP-induced IL-1β secretion is selectively impaired in microglia as compared to hematopoietic macrophages

(2016) Saskia Maria Burm et al.   GLIA

Anti-inflammatory effects of ADAMTS-4 in a mouse model of ischemic stroke

(2016) Sighild Lemarchant et al.   GLIA

Astrocyte calcium signaling: the third wave

(2016) Narges Bazargani et al.   NATURE NEUROSCIENCE

Implications of MMP9 for Blood Brain Barrier Disruption and Hemorrhagic Transformation Following Ischemic Stroke

(2016) Renée J. Turner et al.   Frontiers in Cellular Neuroscience

Rapid endothelial cytoskeletal reorganization enables early blood–brain barrier disruption and long-term ischaemic reperfusion brain injury

(2016) Yejie Shi et al.   Nature Communications

Deletion ofAtf6α impairs astroglial activation and enhances neuronal death following brain ischemia in mice

(2015) Akifumi Yoshikawa et al.   JOURNAL OF NEUROCHEMISTRY

DBZ Regulates Cortical Cell Positioning and Neurite Development by Sustaining the Anterograde Transport of Lis1 and DISC1 through Control of Ndel1 Dual-Phosphorylation

(2015) M. Okamoto et al.   JOURNAL OF NEUROSCIENCE

Emerging role of N-myc downstream-regulated gene 2 (NDRG2) in cancer

(2015) Wei Hu et al.   Oncotarget

Matrix Metalloproteinase-3 Promotes Early Blood–Spinal Cord Barrier Disruption and Hemorrhage and Impairs Long-Term Neurological Recovery after Spinal Cord Injury

(2014) Jee Youn Lee et al.   AMERICAN JOURNAL OF PATHOLOGY

Beneficial effects of gfap/vimentin reactive astrocytes for axonal remodeling and motor behavioral recovery in mice after stroke

(2014) Zhongwu Liu et al.   GLIA

Deletion of N-myc downstream-regulated gene 2 attenuates reactive astrogliosis and inflammatory response in a mouse model of cortical stab injury

(2014) Mika Takarada-Iemata et al.   JOURNAL OF NEUROCHEMISTRY

Glial Scar Borders Are Formed by Newly Proliferated, Elongated Astrocytes That Interact to Corral Inflammatory and Fibrotic Cells via STAT3-Dependent Mechanisms after Spinal Cord Injury

(2013) I. B. Wanner et al.   JOURNAL OF NEUROSCIENCE

MMP-3 Contributes to Nigrostriatal Dopaminergic Neuronal Loss, BBB Damage, and Neuroinflammation in an MPTP Mouse Model of Parkinson’s Disease

(2013) Young Cheul Chung et al.   MEDIATORS OF INFLAMMATION

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

Emerging roles of astrocytes in neural circuit development

(2013) Laura E. Clarke et al.   NATURE REVIEWS NEUROSCIENCE

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

Matrix Metalloproteinase-2-Mediated Occludin Degradation and Caveolin-1-Mediated Claudin-5 Redistribution Contribute to Blood-Brain Barrier Damage in Early Ischemic Stroke Stage

(2012) J. Liu et al.   JOURNAL OF NEUROSCIENCE

Suppression of MMP-9 activity by NDRG2 expression inhibits clear cell renal cell carcinoma invasion

(2012) Jian-Jun Ma et al.   MEDICAL ONCOLOGY

Spatial–temporal expression of NDRG2 in rat brain after focal cerebral ischemia and reperfusion

(2011) Yan Li et al.   BRAIN RESEARCH

PDGFR-β as a Positive Regulator of Tissue Repair in a Mouse Model of Focal Cerebral Ischemia

(2011) Jie Shen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The effect of Ndrg2 expression on astroglial activation

(2011) Toshiaki Takeichi et al.   NEUROCHEMISTRY INTERNATIONAL

Role of Astrocytes in Neurovascular Coupling

(2011) Gabor C. Petzold et al.   NEURON

Blood–Brain Barrier Breakdown in Acute and Chronic Cerebrovascular Disease

(2011) Yi Yang et al.   STROKE

Selective MMP-inhibition with Ro 28-2653 in acute experimental stroke – a magnetic resonance imaging efficacy study

(2010) S. Nagel et al.   BRAIN RESEARCH

Pericytes are required for blood–brain barrier integrity during embryogenesis

(2010) Richard Daneman et al.   NATURE

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Bone morphogenetic protein-4 induced by NDRG2 expression inhibits MMP-9 activity in breast cancer cells

(2009) Soo-Kyung Shon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Suppression of NF- B activity by NDRG2 expression attenuates the invasive potential of highly malignant tumor cells

(2009) A. Kim et al.   CARCINOGENESIS

Reactive Astrocytes Form Scar-Like Perivascular Barriers to Leukocytes during Adaptive Immune Inflammation of the CNS

(2009) R. R. Voskuhl et al.   JOURNAL OF NEUROSCIENCE

Neurorestorative therapies for stroke: underlying mechanisms and translation to the clinic

(2009) Zheng Gang Zhang et al.   LANCET NEUROLOGY

NDRG2: a Myc-repressed gene involved in cancer and cell stress

(2008) Libo Yao et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury

(2008) J. E. Herrmann et al.   JOURNAL OF NEUROSCIENCE

Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke

(2008) Werner Hacke et al.   NEW ENGLAND JOURNAL OF MEDICINE