Implications of MMP9 for Blood Brain Barrier Disruption and Hemorrhagic Transformation Following Ischemic Stroke

Role of Matrix Metalloproteinases in Animal Models of Ischemic Stroke

(2015) Sebastien Lenglet et al.   Current Vascular Pharmacology

Treatment with recombinant tissue plasminogen activator (r-TPA) induces neutrophil degranulation in vitro via defined pathways

(2015) Federico Carbone et al.   VASCULAR PHARMACOLOGY

Activity dependent CAM cleavage and neurotransmission

(2015) Katherine Conant et al.   Frontiers in Cellular Neuroscience

Unbalanced Metalloproteinase-9 and Tissue Inhibitors of Metalloproteinases Ratios Predict Hemorrhagic Transformation of Lesion in Ischemic Stroke Patients Treated with Thrombolysis: Results from the MAGIC Study

(2015) Benedetta Piccardi et al.   Frontiers in Neurology

Effects of Edaravone, a Free Radical Scavenger, on Circulating Levels of MMP-9 and Hemorrhagic Transformation in Patients with Intravenous Thrombolysis Using Low-dose Alteplase

(2014) Atsushi Tsuruoka et al.   Journal of Stroke & Cerebrovascular Diseases

The rtPA increases MMP-9 activity in serum during ischaemic stroke

(2014) Piotr Gołąb et al.   Neurologia i Neurochirurgia Polska

Early reperfusion injury is associated to MMP2 and IL-1β elevation in cortical neurons of rats subjected to middle cerebral artery occlusion

(2014) D. Amantea et al.   NEUROSCIENCE

Analysis of the expression of nine secreted matrix metalloproteinases and their endogenous inhibitors in the brain of mice subjected to ischaemic stroke

(2014) Sébastien Lenglet et al.   THROMBOSIS AND HAEMOSTASIS

Effect of focal mild hypothermia on expression of MMP-9, TIMP-1, Tau-1 and β-APP in rats with cerebral ischaemia/reperfusion injury

(2013) Jing-kun Zhao et al.   BRAIN INJURY

Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): The next decade

(2013) Jennifer Vandooren et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Hemorrhagic Transformation after Ischemic Stroke in Animals and Humans

(2013) Glen C Jickling et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

proMetalloproteinase-10 is associated with brain damage and clinical outcome in acute ischemic stroke

(2013) J. A. Rodríguez et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The roles of MMP-9/TIMP-1 in cerebral edema following experimental acute cerebral infarction in rats

(2013) Dan-Dong Li et al.   NEUROSCIENCE LETTERS

MMP9 Variation After Thrombolysis Is Associated With Hemorrhagic Transformation of Lesion and Death

(2013) Domenico Inzitari et al.   STROKE

Inhibition of MMP-9 Activity following Hypoxic Ischemia in the Developing Brain Using a Highly Specific Inhibitor

(2012) Himani S. Ranasinghe et al.   DEVELOPMENTAL NEUROSCIENCE

Proteolytic Remodeling of the Synaptic Cell Adhesion Molecules (CAMs) by Metzincins in Synaptic Plasticity

(2012) Malgorzata Bajor et al.   NEUROCHEMICAL RESEARCH

Matrix Metalloproteinase-10 Effectively Reduces Infarct Size in Experimental Stroke by Enhancing Fibrinolysis via a Thrombin-Activatable Fibrinolysis Inhibitor–Mediated Mechanism

(2011) J. Orbe et al.   CIRCULATION

Matrix metalloproteinases as drug targets in ischemia/reperfusion injury

(2011) Eline Dejonckheere et al.   DRUG DISCOVERY TODAY

Tissue inhibitor of metalloproteinases-3 mediates the death of immature oligodendrocytes via TNF-α/TACE in focal cerebral ischemia in mice

(2011) Yi Yang et al.   Journal of Neuroinflammation

Matrix Metalloproteinase-9 Mediates Hypoxia-Induced Vascular Leakage in the Brain via Tight Junction Rearrangement

(2010) Alexander T Bauer et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Matrix Metalloproteinase-9 as a Marker for Acute Ischemic Stroke: A Systematic Review

(2010) Maria Ramos-Fernandez et al.   Journal of Stroke & Cerebrovascular Diseases

Matrix metalloproteinases: Evolution, gene regulation and functional analysis in mouse models

(2009) Miriam Fanjul-Fernández et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Neutrophils contribute to intracerebral haemorrhages after treatment with recombinant tissue plasminogen activator following cerebral ischaemia

(2009) Sophie Gautier et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mechanisms of neutrophil transendothelial migration

(2009) Eun Young Choi   Frontiers in Bioscience-Landmark

Rosiglitazone Alone Or in Combination with Tissue Plasminogen Activator Improves Ischemic Brain Injury in an Embolic Model in Rats

(2009) Chen Xu Wang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Minocycline and Tissue-Type Plasminogen Activator for Stroke

(2009) Livia S. Machado et al.   STROKE

Increased expression of serum matrix metalloproteinase-9 in patients with moyamoya disease

(2009) Miki Fujimura et al.   SURGICAL NEUROLOGY

Nitric Oxide Regulation of MMP-9 Activation and Its Relationship to Modifications of the Cysteine Switch†

(2008) Sean M. McCarthy et al.   BIOCHEMISTRY

Protection of cerebral microvasculature after moderate hypothermia following experimental focal cerebral ischemia in mice

(2008) Jan Burk et al.   BRAIN RESEARCH

Tissue Plasminogen Activator (tPA) and Matrix Metalloproteinases in the Pathogenesis of Stroke: Therapeutic Strategies

(2008) Rao Adibhatla et al.   CNS & Neurological Disorders-Drug Targets

Therapeutic application of gene silencing MMP-9 in a middle cerebral artery occlusion-induced focal ischemia rat model

(2008) Qin Hu et al.   EXPERIMENTAL NEUROLOGY

Disassembly of endothelial and epithelial junctions during leukocyte transmigration

(2008) Michael Schnoor   Frontiers in Bioscience-Landmark

Matrix Metalloproteinase-13 is Activated and is found in the Nucleus of Neural Cells after Cerebral Ischemia

(2008) Eloy Cuadrado et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Tissue Inhibitor of Metalloproteinases Protect Blood—Brain Barrier Disruption in Focal Cerebral Ischemia

(2008) Motoaki Fujimoto et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Tissue plasminogen activator (t-PA) promotes neutrophil degranulation and MMP-9 release

(2008) Eloy Cuadrado et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Neutrophil Recruitment under Shear Flow: It's All about Endothelial Cell Rings and Gaps

(2008) Pilar Alcaide et al.   MICROCIRCULATION

Blood-brain barrier tight junction permeability and ischemic stroke

(2008) Karin E. Sandoval et al.   NEUROBIOLOGY OF DISEASE

Brain regional and cellular localization of gelatinase activity in rat that have undergone transient middle cerebral artery occlusion

(2008) D. Amantea et al.   NEUROSCIENCE

Diverse roles of matrix metalloproteinases and tissue inhibitors of metalloproteinases in neuroinflammation and cerebral ischemia

(2008) E. Candelario-Jalil et al.   NEUROSCIENCE

Extension of the Thrombolytic Time Window With Minocycline in Experimental Stroke

(2008) Yoshihiro Murata et al.   STROKE

MMP-9–Positive Neutrophil Infiltration Is Associated to Blood–Brain Barrier Breakdown and Basal Lamina Type IV Collagen Degradation During Hemorrhagic Transformation After Human Ischemic Stroke

(2008) Anna Rosell et al.   STROKE

Etiologic Diagnosis of Ischemic Stroke Subtypes With Plasma Biomarkers

(2008) Joan Montaner et al.   STROKE

High Serum Levels of Endothelin-1 Predict Severe Cerebral Edema in Patients With Acute Ischemic Stroke Treated With t-PA

(2008) Octavio Moldes et al.   STROKE

Pericyte–endothelial cell interaction increases MMP-9 secretion at the blood–brain barrier in vitro

(2007) Alla Zozulya et al.   BRAIN RESEARCH

The regulation of matrix metalloproteinases and their inhibitors

(2007) I CLARK et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

MMPs in the central nervous system: Where the good guys go bad

(2007) S AGRAWAL et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY