Anti-inflammatory effects of ADAMTS-4 in a mouse model of ischemic stroke

Functional polarization of neuroglia: Implications in neuroinflammation and neurological disorders

(2016) Mithilesh Kumar Jha et al.   BIOCHEMICAL PHARMACOLOGY

ADAMTS13-mediated thrombolysis of t-PA-resistant occlusions in ischemic stroke in mice

(2016) F. Denorme et al.   BLOOD

Therapies negating neuroinflammation after brain trauma

(2016) Sarah Hellewell et al.   BRAIN RESEARCH

ADAMTS-4 promotes neurodegeneration in a mouse model of amyotrophic lateral sclerosis

(2016) Sighild Lemarchant et al.   Molecular Neurodegeneration

Immunomodulation by interleukin-33 is protective in stroke through modulation of inflammation

(2015) Paula Korhonen et al.   BRAIN BEHAVIOR AND IMMUNITY

Macrophage activation and its role in repair and pathology after spinal cord injury

(2015) John C. Gensel et al.   BRAIN RESEARCH

Neuroinflammation, Microglia and Mast Cells in the Pathophysiology of Neurocognitive Disorders: A Review

(2015) Stephen Skaper et al.   CNS & Neurological Disorders-Drug Targets

Activation of the nuclear receptor PPARδ is neuroprotective in a transgenic mouse model of Alzheimer’s disease through inhibition of inflammation

(2015) Tarja Malm et al.   Journal of Neuroinflammation

Alternatively activated microglia and macrophages in the central nervous system

(2015) Rafael Franco et al.   PROGRESS IN NEUROBIOLOGY

Recombinant ADAMTS 13 Attenuates Brain Injury After Intracerebral Hemorrhage

(2015) Ping Cai et al.   STROKE

Interleukin-1 and acute brain injury

(2015) Katie N. Murray et al.   Frontiers in Cellular Neuroscience

Rational modulation of the innate immune system for neuroprotection in ischemic stroke

(2015) Diana Amantea et al.   Frontiers in Neuroscience

Low Density Lipoprotein Receptor-related Protein 1 (LRP1)-mediated Endocytic Clearance of a Disintegrin and Metalloproteinase with Thrombospondin Motifs-4 (ADAMTS-4)

(2014) Kazuhiro Yamamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of IL-10 by Chondroitinase ABC Promotes a Distinct Immune Response following Spinal Cord Injury

(2014) Athanasios Didangelos et al.   JOURNAL OF NEUROSCIENCE

Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury

(2014) K. Bartus et al.   JOURNAL OF NEUROSCIENCE

tPA promotes ADAMTS-4-induced CSPG degradation, thereby enhancing neuroplasticity following spinal cord injury

(2014) Sighild Lemarchant et al.   NEUROBIOLOGY OF DISEASE

Inflammatory Cytokines Associated with Degenerative Disc Disease Control Aggrecanase-1 (ADAMTS-4) Expression in Nucleus Pulposus Cells through MAPK and NF-κB

(2013) Ye Tian et al.   AMERICAN JOURNAL OF PATHOLOGY

Phenotypic Transitions of Macrophages Orchestrate Tissue Repair

(2013) Margaret L. Novak et al.   AMERICAN JOURNAL OF PATHOLOGY

Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro

(2013) Vibol Chhor et al.   BRAIN BEHAVIOR AND IMMUNITY

Perilesional Treatment with Chondroitinase ABC and Motor Training Promote Functional Recovery After Stroke in Rats

(2013) L. Gherardini et al.   CEREBRAL CORTEX

Regulation of ADAMTS-1, -4 and -5 expression in human macrophages: Differential regulation by key cytokines implicated in atherosclerosis and novel synergism between TL1A and IL-17

(2013) Tim G. Ashlin et al.   CYTOKINE

ADAMTS proteoglycanases in the physiological and pathological central nervous system

(2013) Sighild Lemarchant et al.   Journal of Neuroinflammation

Complex regulation of acute and chronic neuroinflammatory responses in mouse models deficient for nuclear factor kappa B p50 subunit

(2013) Taisia Rolova et al.   NEUROBIOLOGY OF DISEASE

ADAMTS1, ADAMTS5, ADAMTS9 and aggrecanase-generated proteoglycan fragments are induced following spinal cord injury in mouse

(2013) Kadir Demircan et al.   NEUROSCIENCE LETTERS

Recombinant ADAMTS13 reduces tissue plasminogen activator-induced hemorrhage after stroke in mice

(2012) Lixiang Wang et al.   ANNALS OF NEUROLOGY

ADAMTS-1 and ADAMTS-4 Levels Are Elevated in Thoracic Aortic Aneurysms and Dissections

(2012) Pingping Ren et al.   ANNALS OF THORACIC SURGERY

Delayed treatment with chondroitinase ABC promotes sensorimotor recovery and plasticity after stroke in aged rats

(2012) Sara Soleman et al.   BRAIN

Anti-angiogenic properties of ADAMTS-4 in vitro

(2012) Yi-Ping Hsu et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

WIN-34B, a new herbal medicine, inhibits the inflammatory response by inactivating IκB-α phosphorylation and mitogen activated protein kinase pathways in fibroblast-like synoviocytes

(2012) Jeong-Eun Huh et al.   JOURNAL OF ETHNOPHARMACOLOGY

The endogenous proteoglycan-degrading enzyme ADAMTS-4 promotes functional recovery after spinal cord injury

(2012) Ryoji Tauchi et al.   Journal of Neuroinflammation

Glutamate Controls tPA Recycling by Astrocytes, Which in Turn Influences Glutamatergic Signals

(2012) F. Casse et al.   JOURNAL OF NEUROSCIENCE

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

ADAMTS-13 is produced by glial cells and upregulated after spinal cord injury

(2012) Ryoji Tauchi et al.   NEUROSCIENCE LETTERS

Selective Decline of Synaptic Protein Levels in the Frontal Cortex of Female Mice Deficient in the Extracellular Metalloproteinase ADAMTS1

(2012) Matthew D. Howell et al.   PLoS One

Regulated Proteolytic Processing of Reelin through Interplay of Tissue Plasminogen Activator (tPA), ADAMTS-4, ADAMTS-5, and Their Modulators

(2012) Dimitrije Krstic et al.   PLoS One

Intracerebral chondroitinase ABC and heparan sulfate proteoglycan glypican improve outcome from chronic stroke in rats

(2012) J. J. Hill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The pro- and anti-inflammatory properties of the cytokine interleukin-6

(2011) Jürgen Scheller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Inflammation in osteoarthritis

(2011) Mary B. Goldring et al.   CURRENT OPINION IN RHEUMATOLOGY

Multiple cellular and molecular mechanisms Are involved in human Aβ clearance by transplanted adult astrocytes

(2011) Rea Pihlaja et al.   GLIA

Interleukin-6 upregulates expression of ADAMTS-4 in fibroblast-like synoviocytes from patients with rheumatoid arthritis

(2011) Yoshikuni MIMATA et al.   International Journal of Rheumatic Diseases

Manipulating the glial scar: Chondroitinase ABC as a therapy for spinal cord injury

(2010) Elizabeth J. Bradbury et al.   BRAIN RESEARCH BULLETIN

The Low-Density Lipoprotein Receptor-Related Protein 1 Mediates Tissue-Type Plasminogen Activator-Induced Microglial Activation in the Ischemic Brain

(2009) Chen Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

von Willebrand factor-cleaving protease ADAMTS13 reduces ischemic brain injury in experimental stroke

(2009) B.-Q. Zhao et al.   BLOOD

ADAMTS-9 expression is up-regulated following transient middle cerebral artery occlusion (tMCAo) in the rat

(2009) Martin J. Reid et al.   NEUROSCIENCE LETTERS

Low-density lipoprotein receptors regulate microglial inflammation through c-Jun N-terminal kinase

(2008) Ana Pocivavsek et al.   GLIA

ADAMTS-4 and -8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaques

(2007) Dick Wågsäter et al.   ATHEROSCLEROSIS

Multimodal signaling by the ADAMTSs (a disintegrin and metalloproteinase with thrombospondin motifs) promotes neurite extension

(2007) Michelle G. Hamel et al.   EXPERIMENTAL NEUROLOGY