Cellular regeneration strategies for macular degeneration: past, present and future
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Title
Cellular regeneration strategies for macular degeneration: past, present and future
Authors
Keywords
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Journal
EYE
Volume 32, Issue 5, Pages 946-971
Publisher
Springer Nature
Online
2018-03-01
DOI
10.1038/s41433-018-0061-z
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Note: Only part of the references are listed.- OCT angiography documented reperfusion of translocated autologous full thickness RPE-choroid graft for complicated neovascular age-related macular degeneration
- (2017) M Veckeneer et al. EYE
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- (2017) J O Mills et al. EYE
- Using CRISPR-Cas9 to Generate Gene-Corrected Autologous iPSCs for the Treatment of Inherited Retinal Degeneration
- (2017) Erin R. Burnight et al. MOLECULAR THERAPY
- Stimulation of functional neuronal regeneration from Müller glia in adult mice
- (2017) Nikolas L. Jorstad et al. NATURE
- The promise of stem cell-based therapeutics in ophthalmology
- (2017) Nitza Goldenberg-Cohen et al. Neural Regeneration Research
- Vision Loss after Intravitreal Injection of Autologous “Stem Cells” for AMD
- (2017) Ajay E. Kuriyan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration
- (2017) NEW ENGLAND JOURNAL OF MEDICINE
- A Promising Tool in Retina Regeneration: Current Perspectives and Challenges When Using Mesenchymal Progenitor Stem Cells in Veterinary and Human Ophthalmological Applications
- (2017) Anna Cislo-Pakuluk et al. Stem Cell Reviews and Reports
- An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age-Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure
- (2017) Dean Hallam et al. STEM CELLS
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- (2017) Allison E. Songstad et al. Stem Cells Translational Medicine
- A Promising Tool in Retina Regeneration: Current Perspectives and Challenges When Using Mesenchymal Progenitor Stem Cells in Veterinary and Human Ophthalmological Applications
- (2017) Anna Cislo-Pakuluk et al. Stem Cell Reviews and Reports
- iPSC-Derived Retina Transplants Improve Vision in rd1 End-Stage Retinal-Degeneration Mice
- (2017) Michiko Mandai et al. Stem Cell Reports
- Isolation and Comparative Transcriptome Analysis of Human Fetal and iPSC-Derived Cone Photoreceptor Cells
- (2017) Emily Welby et al. Stem Cell Reports
- Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors
- (2017) Anai Gonzalez-Cordero et al. Stem Cell Reports
- The Developmental Stage of Adult Human Stem Cell-Derived Retinal Pigment Epithelium Cells Influences Transplant Efficacy for Vision Rescue
- (2017) Richard J. Davis et al. Stem Cell Reports
- Towards Treatment of Stargardt Disease: Workshop Organized and Sponsored by the Foundation Fighting Blindness
- (2017) Avery E. Sears et al. Translational Vision Science & Technology
- Human iPSC disease modelling reveals functional and structural defects in retinal pigment epithelial cells harbouring the m.3243A > G mitochondrial DNA mutation
- (2017) Valeria Chichagova et al. Scientific Reports
- Three-dimensional printing of the retina
- (2016) Barbara Lorber et al. CURRENT OPINION IN OPHTHALMOLOGY
- Natural underlying mtDNA heteroplasmy as a potential source of intra‐person hiPSC variability
- (2016) Ester Perales‐Clemente et al. EMBO JOURNAL
- Leading causes of certifiable visual loss in England and Wales during the year ending 31 March 2013
- (2016) A Quartilho et al. EYE
- Structural and molecular changes in the aging choroid: implications for age-related macular degeneration
- (2016) K R Chirco et al. EYE
- Transcriptional Reactivation of OTX2, RX1 and SIX3 during Reprogramming Contributes to the Generation of RPE Cells from Human iPSCs
- (2016) Peng Li et al. International Journal of Biological Sciences
- Concise Review: Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer: A Horse in the Race?
- (2016) Don P. Wolf et al. STEM CELLS
- Cell-Based Therapy for Degenerative Retinal Disease
- (2016) Marco Zarbin TRENDS IN MOLECULAR MEDICINE
- Retinal transplantation of photoreceptors results in donor–host cytoplasmic exchange
- (2016) Tiago Santos-Ferreira et al. Nature Communications
- In Pursuit of Authenticity: Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Clinical Applications
- (2016) Kiyoharu J. Miyagishima et al. Stem Cells Translational Medicine
- Autologous Neurosensory Retinal Free Flap for Closure of Refractory Myopic Macular Holes
- (2016) Dilraj S. Grewal et al. JAMA Ophthalmology
- Xeno-Free and Defined Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells Functionally Integrate in a Large-Eyed Preclinical Model
- (2016) Alvaro Plaza Reyes et al. Stem Cell Reports
- Successful Transplantation of Retinal Pigment Epithelial Cells from MHC Homozygote iPSCs in MHC-Matched Models
- (2016) Sunao Sugita et al. Stem Cell Reports
- Efficacy and Safety of Human Retinal Progenitor Cells
- (2016) Ma'ayan Semo et al. Translational Vision Science & Technology
- Differentiation of human embryonic stem cells into cone photoreceptors through simultaneous inhibition of BMP, TGFβ and Wnt signaling
- (2015) Shufeng Zhou et al. DEVELOPMENT
- Stem cells in clinical trials for treatment of retinal degeneration
- (2015) Henry Klassen EXPERT OPINION ON BIOLOGICAL THERAPY
- Retinal pigment epithelium transplantation: concepts, challenges and future prospects
- (2015) P Alexander et al. EYE
- Delivery strategies for treatment of age-related ocular diseases: From a biological understanding to biomaterial solutions
- (2015) Vianney Delplace et al. JOURNAL OF CONTROLLED RELEASE
- Human Umbilical Tissue-Derived Cells Promote Synapse Formation and Neurite Outgrowth via Thrombospondin Family Proteins
- (2015) Sehwon Koh et al. JOURNAL OF NEUROSCIENCE
- Stem cells in age-related macular degeneration and Stargardt's macular dystrophy
- (2015) Janet S Sunness LANCET
- Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies
- (2015) Steven D Schwartz et al. LANCET
- RIKEN suspends first clinical trial involving induced pluripotent stem cells
- (2015) Ken Garber NATURE BIOTECHNOLOGY
- Transplantation of human embryonic stem cell-derived retinal tissue in two primate models of retinal degeneration
- (2015) Hiroshi Shirai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cellular strategies for retinal repair by photoreceptor replacement
- (2015) Sujatha A. Jayakody et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Transplantation of Photoreceptor Precursors Isolated via a Cell Surface Biomarker Panel from Embryonic Stem Cell-Derived Self-Forming Retina
- (2015) Jorn Lakowski et al. STEM CELLS
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- (2013) Patrick H. Warnke et al. Acta Biomaterialia
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- Immunogenicity of induced pluripotent stem cells
- (2011) Tongbiao Zhao et al. NATURE
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- (2011) Mototsugu Eiraku et al. NATURE
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- (2011) Fabian Thieltges et al. OPHTHALMIC RESEARCH
- Ciliary neurotrophic factor delivered by encapsulated cell intraocular implants for treatment of geographic atrophy in age-related macular degeneration
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- (2010) Ying Yang et al. PLoS One
- Long-Term Survival of Photoreceptors Transplanted into the Adult Murine Neural Retina Requires Immune Modulation
- (2010) Emma L. West et al. STEM CELLS
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- (2010) Sara Gualdoni et al. STEM CELLS
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- (2010) Serena G. Giannelli et al. STEM CELLS
- Regenerative medicine for retinal diseases: activating endogenous repair mechanisms
- (2010) M.O. Karl et al. TRENDS IN MOLECULAR MEDICINE
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- Distribution of Müller stem cells within the neural retina: Evidence for the existence of a ciliary margin-like zone in the adult human eye
- (2009) Bhairavi Bhatia et al. EXPERIMENTAL EYE RESEARCH
- Surgery for CNV and autologous choroidal RPE patch transplantation: exposing the submacular space
- (2009) Matteo Giuseppe Cereda et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction
- (2009) F. Osakada et al. JOURNAL OF CELL SCIENCE
- Functional Cone Rescue by RdCVF Protein in a Dominant Model of Retinitis Pigmentosa
- (2009) Ying Yang et al. MOLECULAR THERAPY
- Cells previously identified as retinal stem cells are pigmented ciliary epithelial cells
- (2009) S. A. Cicero et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modeling early retinal development with human embryonic and induced pluripotent stem cells
- (2009) J. S. Meyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genetic Basis of Inherited Macular Dystrophies and Implications for Stem Cell Therapy
- (2009) Carla B. Mellough et al. STEM CELLS
- Vision Improvement in Retinal Degeneration Patients by Implantation of Retina Together with Retinal Pigment Epithelium
- (2008) Norman D. Radtke et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Retinal cells integrate into the outer nuclear layer and differentiate into mature photoreceptors after subretinal transplantation into adult mice
- (2008) Udo Bartsch et al. EXPERIMENTAL EYE RESEARCH
- The transcriptome of retinal Müller glial cells
- (2008) Karin Roesch et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells
- (2008) Fumitaka Osakada et al. NATURE BIOTECHNOLOGY
- Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inflammatory/immune responses
- (2008) H. Ohtaki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Culture-induced increase in alpha integrin subunit expression in retinal pigment epithelium is important for improved resurfacing of aged human Bruch's membrane
- (2007) Vamsi K. Gullapalli et al. EXPERIMENTAL EYE RESEARCH
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