Connective Tissue Growth Factor Promotes Efficient Generation of Human Induced Pluripotent Stem Cell-Derived Choroidal Endothelium

Induced Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium: A Comparative Study Between Cell Lines and Differentiation Methods

(2016) Lyndsay L. Leach et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Histopathological Insights Into Choroidal Vascular Loss in Clinically Documented Cases of Age-Related Macular Degeneration

(2016) Johanna M. Seddon et al.   JAMA Ophthalmology

The C-Terminal Module IV of Connective Tissue Growth Factor, Through EGFR/Nox1 Signaling, Activates the NF-κB Pathway and Proinflammatory Factors in Vascular Smooth Muscle Cells

(2015) Raúl R. Rodrigues-Diez et al.   ANTIOXIDANTS & REDOX SIGNALING

Molecular response of chorioretinal endothelial cells to complement injury: implications for macular degeneration

(2015) Shemin Zeng et al.   JOURNAL OF PATHOLOGY

A qPCR ScoreCard quantifies the differentiation potential of human pluripotent stem cells

(2015) Alexander M Tsankov et al.   NATURE BIOTECHNOLOGY

Complement activation and choriocapillaris loss in early AMD: Implications for pathophysiology and therapy

(2015) S. Scott Whitmore et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Using patient-specific induced pluripotent stem cells to interrogate the pathogenicity of a novel retinal pigment epithelium-specific 65 kDa cryptic splice site mutation and confirm eligibility for enrollment into a clinical gene augmentation trial

(2015) Budd A. Tucker et al.   Translational Research

Comparison of Retinal and Choriocapillaris Thicknesses Following Sitting to Supine Transition in Healthy Individuals and Patients With Age-Related Macular Degeneration

(2015) David R. P. Almeida et al.   JAMA Ophthalmology

The Membrane Attack Complex in Aging Human Choriocapillaris

(2014) Robert F. Mullins et al.   AMERICAN JOURNAL OF PATHOLOGY

Choriocapillaris breakdown precedes retinal degeneration in age-related macular degeneration

(2014) Antje Biesemeier et al.   NEUROBIOLOGY OF AGING

The Eukaryotic Promoter Database: expansion of EPDnew and new promoter analysis tools

(2014) René Dreos et al.   NUCLEIC ACIDS RESEARCH

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Loss of CD34 Expression in Aging Human Choriocapillaris Endothelial Cells

(2014) Elliott H. Sohn et al.   PLoS One

Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs

(2014) Xiufeng Zhong et al.   Nature Communications

A Multiplex High-Throughput Gene Expression Assay to Simultaneously Detect Disease and Functional Markers in Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium

(2014) Marc Ferrer et al.   Stem Cells Translational Medicine

Characterization of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium Cell Sheets Aiming for Clinical Application

(2014) Hiroyuki Kamao et al.   Stem Cell Reports

TWEAK transactivation of the epidermal growth factor receptor mediates renal inflammation

(2013) Sandra Rayego-Mateos et al.   JOURNAL OF PATHOLOGY

Connective tissue growth factor (CCN2) in blood vessels

(2013) Markella Ponticos   VASCULAR PHARMACOLOGY

Rapid and Efficient Directed Differentiation of Human Pluripotent Stem Cells Into Retinal Pigmented Epithelium

(2013) David E. Buchholz et al.   Stem Cells Translational Medicine

Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa

(2013) Budd A Tucker et al.   eLife

CCN2/CTGF regulates neovessel formation via targeting structurally conserved cystine knot motifs in multiple angiogenic regulators

(2012) Liya Pi et al.   FASEB JOURNAL

iPS cell modeling of Best disease: insights into the pathophysiology of an inherited macular degeneration

(2012) Ruchira Singh et al.   HUMAN MOLECULAR GENETICS

EPD and EPDnew, high-quality promoter resources in the next-generation sequencing era

(2012) René Dreos et al.   NUCLEIC ACIDS RESEARCH

Use of a Synthetic Xeno-Free Culture Substrate for Induced Pluripotent Stem Cell Induction and Retinal Differentiation

(2012) Budd A. Tucker et al.   Stem Cells Translational Medicine

Trypan Blue staining method for quenching the autofluorescence of RPE cells for improving protein expression analysis

(2011) Girish K. Srivastava et al.   EXPERIMENTAL EYE RESEARCH

Elevated membrane attack complex in human choroid with high risk complement factor H genotypes

(2011) Robert F. Mullins et al.   EXPERIMENTAL EYE RESEARCH

CTGF Promotes Inflammatory Cell Infiltration of the Renal Interstitium by Activating NF- B

(2009) E. Sanchez-Lopez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Taguchi methodology as a statistical tool for biotechnological applications: A critical appraisal

(2008) Ravella Sreenivas Rao et al.   Biotechnology Journal

Functions and mechanisms of action of CCN matricellular proteins

(2008) Chih-Chiun Chen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A protocol for removal of antibiotic resistance cassettes from human embryonic stem cells genetically modified by homologous recombination or transgenesis

(2008) Richard P Davis et al.   Nature Protocols