Using Zinc Finger Nuclease Technology to Generate CRX-Reporter Human Embryonic Stem Cells as a Tool to Identify and Study the Emergence of Photoreceptors Precursors During Pluripotent Stem Cell Differentiation

IGF-1 Signaling Plays an Important Role in the Formation of Three-Dimensional Laminated Neural Retina and Other Ocular Structures From Human Embryonic Stem Cells

(2015) Carla B. Mellough et al.   STEM CELLS

Generation of retinal ganglion cells with functional axons from human induced pluripotent stem cells

(2015) Taku Tanaka et al.   Scientific Reports

An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage

(2014) Eli J. Fine et al.   NUCLEIC ACIDS RESEARCH

Lab generated retina: Realizing the dream

(2014) CARLA B. MELLOUGH et al.   VISUAL NEUROSCIENCE

Efficient Editing of Malaria Parasite Genome Using the CRISPR/Cas9 System

(2014) C. Zhang et al.   mBio

Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs

(2014) Xiufeng Zhong et al.   Nature Communications

Self-Formation of Optic Cups and Storable Stratified Neural Retina from Human ESCs

(2012) Tokushige Nakano et al.   Cell Stem Cell

Regulation of eukaryotic gene expression by the untranslated gene regions and other non-coding elements

(2012) Lucy W. Barrett et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Efficient Stage-Specific Differentiation of Human Pluripotent Stem Cells Toward Retinal Photoreceptor Cells

(2012) Carla B. Mellough et al.   STEM CELLS

Self-organizing optic-cup morphogenesis in three-dimensional culture

(2011) Mototsugu Eiraku et al.   NATURE

Concise Review: Putting a Finger on Stem Cell Biology: Zinc Finger Nuclease-Driven Targeted Genetic Editing in Human Pluripotent Stem Cells

(2011) Joseph Collin et al.   STEM CELLS

Cone and rod photoreceptor transplantation in models of the childhood retinopathy Leber congenital amaurosis using flow-sorted Crx-positive donor cells

(2010) J. Lakowski et al.   HUMAN MOLECULAR GENETICS

Generation, Purification and Transplantation of Photoreceptors Derived from Human Induced Pluripotent Stem Cells

(2010) Deepak A. Lamba et al.   PLoS One

Gene Targeting of a Disease-Related Gene in Human Induced Pluripotent Stem and Embryonic Stem Cells

(2009) Jizhong Zou et al.   Cell Stem Cell

Robust marking of photoreceptor cells and pinealocytes with several reporters under control of theCrxgene

(2009) Maria Samson et al.   DEVELOPMENTAL DYNAMICS

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

(2009) Dirk Hockemeyer et al.   NATURE BIOTECHNOLOGY

Silencing of the expression of pluripotent driven-reporter genes stably transfected into human pluripotent cells

(2008) Rebecca Stewart et al.   Regenerative Medicine