The new paradigm: retinal pigment epithelium cells generated from embryonic or induced pluripotent stem cells

Retinal Pigment Epithelium-Derived CTLA-2  Induces TGF -Producing T Regulatory Cells

(2014) S. Sugita et al.   JOURNAL OF IMMUNOLOGY

iPS cell technology in regenerative medicine

(2010) Christopher J. Lengner   Annals of the New York Academy of Sciences

The disruption of the rod-derived cone viability gene leads to photoreceptor dysfunction and susceptibility to oxidative stress

(2010) T Cronin et al.   CELL DEATH AND DIFFERENTIATION

Human retinal pigment epithelium-induced CD4+CD25+ regulatory T cells suppress activation of intraocular effector T cells

(2010) Shintaro Horie et al.   CLINICAL IMMUNOLOGY

MicroRNA-204/211 alters epithelial physiology

(2010) Fei E. Wang et al.   FASEB JOURNAL

Suppression of Ca2+ signaling in a mouse model of Best disease

(2010) Y. Zhang et al.   HUMAN MOLECULAR GENETICS

Molecular signature of primary retinal pigment epithelium and stem-cell-derived RPE cells

(2010) Jo-Ling Liao et al.   HUMAN MOLECULAR GENETICS

Transcriptome analysis and molecular signature of human retinal pigment epithelium

(2010) N.V. Strunnikova et al.   HUMAN MOLECULAR GENETICS

Light-Evoked Responses of the Retinal Pigment Epithelium: Changes Accompanying Photoreceptor Loss in the Mouse

(2010) Ivy S. Samuels et al.   JOURNAL OF NEUROPHYSIOLOGY

Epigenetic memory in induced pluripotent stem cells

(2010) K. Kim et al.   NATURE

Phagocytosis of Retinal Rod and Cone Photoreceptors

(2010) Brian M. Kevany et al.   PHYSIOLOGY

Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

(2010) J. Hanna et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis Pigmentosa

(2010) V. Busskamp et al.   SCIENCE

Hemangioblastic Derivatives from Human Induced Pluripotent Stem Cells Exhibit Limited Expansion and Early Senescence

(2010) Qiang Feng et al.   STEM CELLS

The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision

(2010) Johannes von Lintig et al.   TRENDS IN BIOCHEMICAL SCIENCES

Regenerative medicine for retinal diseases: activating endogenous repair mechanisms

(2010) M.O. Karl et al.   TRENDS IN MOLECULAR MEDICINE

IFNγ regulates retinal pigment epithelial fluid transport

(2009) Rong Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Unraveling a Multifactorial Late-Onset Disease: From Genetic Susceptibility to Disease Mechanisms for Age-Related Macular Degeneration

(2009) Anand Swaroop et al.   Annual Review of Genomics and Human Genetics

Directed Differentiation of Human Embryonic Stem Cells into Functional Retinal Pigment Epithelium Cells

(2009) Maria Idelson et al.   Cell Stem Cell

Epithelial cell surface polarity: the early steps

(2009) Lene et al.   Frontiers in Bioscience-Landmark

In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction

(2009) F. Osakada et al.   JOURNAL OF CELL SCIENCE

CO2-induced ion and fluid transport in human retinal pigment epithelium

(2009) Jeffrey Adijanto et al.   JOURNAL OF GENERAL PHYSIOLOGY

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

(2009) Ulrich Wellner et al.   NATURE CELL BIOLOGY

Stepwise differentiation of pluripotent stem cells into retinal cells

(2009) Fumitaka Osakada et al.   Nature Protocols

RPE65: Role in the Visual Cycle, Human Retinal Disease, and Gene Therapy

(2009) Xue Cai et al.   OPHTHALMIC GENETICS

Microglia in the Mouse Retina Alter the Structure and Function of Retinal Pigmented Epithelial Cells: A Potential Cellular Interaction Relevant to AMD

(2009) Wenxin Ma et al.   PLoS One

Protective Effects of Human iPS-Derived Retinal Pigment Epithelium Cell Transplantation in the Retinal Dystrophic Rat

(2009) Amanda-Jayne Carr et al.   PLoS One

Genetic ablation of retinal pigment epithelial cells reveals the adaptive response of the epithelium and impact on photoreceptors

(2009) R. Longbottom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling early retinal development with human embryonic and induced pluripotent stem cells

(2009) J. S. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The dynamic nature of Bruch's membrane

(2009) J.C. Booij et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Derivation of Functional Retinal Pigmented Epithelium from Induced Pluripotent Stem Cells

(2009) David E. Buchholz et al.   STEM CELLS

Long-Term Safety and Function of RPE from Human Embryonic Stem Cells in Preclinical Models of Macular Degeneration

(2009) Bin Lu et al.   STEM CELLS

Alternative promoter use in eye development: the complex role and regulation of the transcription factor MITF

(2008) K. Bharti et al.   DEVELOPMENT

Elucidating the phenomenon of HESC-derived RPE: Anatomy of cell genesis, expansion and retinal transplantation

(2008) Anthony Vugler et al.   EXPERIMENTAL NEUROLOGY

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

(2008) S.-M. Park et al.   GENES & DEVELOPMENT

Age-related macular degeneration: activation of innate immunity system via pattern recognition receptors

(2008) K. Kaarniranta et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells

(2008) Fumitaka Osakada et al.   NATURE BIOTECHNOLOGY

From cells to organs: building polarized tissue

(2008) David M. Bryant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY