Influence of arachidonyl-2′-chloroethylamide, a selective cannabinoid CB1 receptor agonist, on the anticonvulsant and acute side-effect potentials of clobazam, lacosamide, and pregabalin in the maximal electroshock-induced seizure model and chimney test i

Current understanding of the mechanism of action of the antiepileptic drug lacosamide

(2015) Michael A. Rogawski et al.   EPILEPSY RESEARCH

The adverse health effects of synthetic cannabinoids with emphasis on psychosis-like effects

(2015) Jan van Amsterdam et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Functional Characterization of the 1,5-Benzodiazepine Clobazam and Its Major Active Metabolite N-Desmethylclobazam at Human GABAA Receptors Expressed in Xenopus laevis Oocytes

(2015) Harriet Hammer et al.   PLoS One

Efficacy and tolerability of add-on lacosamide in children with Lennox-Gastaut syndrome

(2014) S. Grosso et al.   ACTA NEUROLOGICA SCANDINAVICA

Anticonvulsant Effects ofN-Arachidonoyl-Serotonin, a Dual Fatty Acid Amide Hydrolase Enzyme and Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Blocker, on Experimental Seizures: The Roles of Cannabinoid CB1 Receptors and TRPV1 Channels

(2014) Luciano R. Vilela et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Cannabidiol and medical marijuana for the treatment of epilepsy

(2014) Gary Mathern et al.   EPILEPSIA

The case for assessing cannabidiol in epilepsy

(2014) Maria Roberta Cilio et al.   EPILEPSIA

The case for medical marijuana in epilepsy

(2014) Edward Maa et al.   EPILEPSIA

Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders

(2014) Orrin Devinsky et al.   EPILEPSIA

Influence of WIN 55,212-2 on the anticonvulsant and acute neurotoxic potential of clobazam and lacosamide in the maximal electroshock-induced seizure model and chimney test in mice

(2014) Magdalena Florek-Luszczki et al.   EPILEPSY RESEARCH

Lacosamide for the treatment of epilepsy

(2014) Stefano de Biase et al.   Expert Opinion on Drug Metabolism & Toxicology

Effects of WIN 55,212-2 (a non-selective cannabinoid CB1 and CB2 receptor agonist) on the protective action of various classical antiepileptic drugs in the mouse 6 Hz psychomotor seizure model

(2014) Magdalena Florek-Luszczki et al.   JOURNAL OF NEURAL TRANSMISSION

Adverse Health Effects of Marijuana Use

(2014) Nora D. Volkow et al.   NEW ENGLAND JOURNAL OF MEDICINE

Third-generation antiepileptic drugs: mechanisms of action, pharmacokinetics and interactions

(2014) Jarogniew J. Łuszczki   Pharmacological Reports

Synergistic interaction of pregabalin with the synthetic cannabinoid WIN 55,212-2 mesylate in the hot-plate test in mice: an isobolographic analysis

(2014) Jarogniew J. Łuszczki et al.   Pharmacological Reports

Clobazam and Its Active Metabolite N-desmethylclobazam Display Significantly Greater Affinities for α2- versus α1-GABAA–Receptor Complexes

(2014) Henrik Sindal Jensen et al.   PLoS One

Experience in the use of clobazam in the treatment of Lennox–Gastaut syndrome

(2014) Gabriela Purcarin et al.   Therapeutic Advances in Neurological Disorders

Development of lacosamide for the treatment of partial-onset seizures

(2013) Pamela Doty et al.   Annals of the New York Academy of Sciences

Drug Interactions with the Newer Antiepileptic Drugs (AEDs)—Part 1: Pharmacokinetic and Pharmacodynamic Interactions Between AEDs

(2013) Philip N. Patsalos   CLINICAL PHARMACOKINETICS

Effects of cannabinoids and endocannabinoid hydrolysis inhibition on pentylenetetrazole-induced seizure and electroencephalographic activity in rats

(2013) Luciano R. Vilela et al.   EPILEPSY RESEARCH

Effects of WIN 55,212-2 mesylate on the anticonvulsant action of lamotrigine, oxcarbazepine, pregabalin and topiramate against maximal electroshock-induced seizures in mice

(2013) Jarogniew J. Luszczki et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Interactions between angiotensin AT1receptor antagonists and second-generation antiepileptic drugs in the test of maximal electroshock

(2013) Krzysztof Łukawski et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

The brain effects of cannabis in healthy adolescents and in adolescents with schizophrenia: a systematic review

(2013) Anthony James et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Clobazam

(2012) Lily P. H. Yang et al.   CNS DRUGS

Antiepileptic drug monotherapy versus polytherapy

(2012) Linda J. Stephen et al.   CURRENT OPINION IN NEUROLOGY

How theories evolved concerning the mechanism of action of barbiturates

(2012) Wolfgang Löscher et al.   EPILEPSIA

Long-term safety and efficacy of clobazam for Lennox–Gastaut syndrome: Interim results of an open-label extension study

(2012) Yu-Tze Ng et al.   EPILEPSY & BEHAVIOR

Pharmacokinetic and pharmacodynamic profile of pregabalin and its role in the treatment of epilepsy

(2012) Andreas Schulze-Bonhage   Expert Opinion on Drug Metabolism & Toxicology

Patterns of treatment response in newly diagnosed epilepsy

(2012) M. J. Brodie et al.   NEUROLOGY

Effect of ACEA—a selective cannabinoid CB1 receptor agonist on the protective action of different antiepileptic drugs in the mouse pentylenetetrazole-induced seizure model

(2012) Marta Andres-Mach et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Effects of valproate on glutamate metabolism in rat brain slices: A 13C NMR study

(2011) Maha El Hage et al.   EPILEPSY RESEARCH

Pregabalin is a potent and selective ligand for α2δ-1 and α2δ-2 calcium channel subunits

(2011) Zheng Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Efficacy and safety of pregabalin versus lamotrigine in patients with newly diagnosed partial seizures: a phase 3, double-blind, randomised, parallel-group trial

(2011) Patrick Kwan et al.   LANCET NEUROLOGY

Effects of antiepileptic drugs on GABA release from rat and human neocortical synaptosomes

(2011) M. Kammerer et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

L-Type Calcium Channel Mediates Anticonvulsant Effect of Cannabinoids in Acute and Chronic Murine Models of Seizure

(2011) Nima Naderi et al.   NEUROCHEMICAL RESEARCH

Enhancement of the behavioral effects of endogenous and exogenous cannabinoid agonists by phenylmethyl sulfonyl fluoride

(2011) R.E. Vann et al.   NEUROPHARMACOLOGY

Synthetic cannabinoid WIN 55,212-2 mesylate enhances the protective action of four classical antiepileptic drugs against maximal electroshock-induced seizures in mice

(2011) Jarogniew J. Luszczki et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Effects of WIN 55,212-2 mesylate (a synthetic cannabinoid) on the protective action of clonazepam, ethosuximide, phenobarbital and valproate against pentylenetetrazole-induced clonic seizures in mice

(2011) Jarogniew J. Luszczki et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Phenobarbital but Not Diazepam Reduces AMPA/kainate Receptor Mediated Currents and Exerts Opposite Actions on Initial Seizures in the Neonatal Rat Hippocampus

(2011) Romain Nardou et al.   Frontiers in Cellular Neuroscience

Involvement of nitrergic system in the anticonvulsant effect of the cannabinoid CB1 agonist ACEA in the pentylenetetrazole-induced seizure in mice

(2009) Arash Bahremand et al.   EPILEPSY RESEARCH

Pregabalin: Preliminary Experience in Intractable Childhood Epilepsy

(2009) Mohammed M.S. Jan et al.   PEDIATRIC NEUROLOGY

Effect of arachidonyl-2′-chloroethylamide, a selective cannabinoid CB1 receptor agonist, on the protective action of the various antiepileptic drugs in the mouse maximal electroshock-induced seizure model

(2009) Jarogniew J. Luszczki et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Reduction of secondarily generalized tonic–clonic (SGTC) seizures with pregabalin

(2008) Deborah E. Briggs et al.   EPILEPSY RESEARCH

Add-on treatment with pregabalin for partial seizures with or without generalisation: Pooled data analysis of four randomised placebo-controlled trials

(2008) Antonio Gil-Nagel et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY