Mechanistic Study of Suzuki-Miyaura Cross-Coupling Reactions of Amides Mediated by [Pd(NHC)(allyl)Cl] Precatalysts

Rapidly Activating Pd-Precatalyst for Suzuki–Miyaura and Buchwald–Hartwig Couplings of Aryl Esters

(2017) Amira H. Dardir et al.   JOURNAL OF ORGANIC CHEMISTRY

Pd-PEPPSI: Pd-NHC Precatalyst for Suzuki–Miyaura Cross-Coupling Reactions of Amides

(2017) Peng Lei et al.   JOURNAL OF ORGANIC CHEMISTRY

Ni-Catalyzed Alkene Carboacylation via Amide C–N Bond Activation

(2017) James A. Walker et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Suzuki–Miyaura Coupling of Aryl Esters

(2017) Taoufik Ben Halima et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synergistic Visible-Light Photoredox/Nickel-Catalyzed Synthesis of Aliphatic Ketones via N–C Cleavage of Imides

(2017) Javad Amani et al.   ORGANIC LETTERS

Ni-Catalyzed Reductive Cross-Coupling of Amides with Aryl Iodide Electrophiles via C–N Bond Activation

(2017) Shengyang Ni et al.   ORGANIC LETTERS

Amide to Alkyne Interconversion via a Nickel/Copper-Catalyzed Deamidative Cross-Coupling of Aryl and Alkenyl Amides

(2017) Watchara Srimontree et al.   ORGANIC LETTERS

Decarbonylative Cyanation of Amides by Palladium Catalysis

(2017) Shicheng Shi et al.   ORGANIC LETTERS

A General Method for Two-Step Transamidation of Secondary Amides Using Commercially Available, Air- and Moisture-Stable Palladium/NHC (N-Heterocyclic Carbene) Complexes

(2017) Guangrong Meng et al.   ORGANIC LETTERS

Pd-PEPPSI: A General Pd-NHC Precatalyst for Suzuki–Miyaura Cross-Coupling of Esters by C–O Cleavage

(2017) Shicheng Shi et al.   ORGANOMETALLICS

Mechanism of the Suzuki–Miyaura Cross-Coupling Reaction Mediated by [Pd(NHC)(allyl)Cl] Precatalysts

(2017) Giulia Magi Meconi et al.   ORGANOMETALLICS

Ni-mediated C–N activation of amides and derived catalytic transformations

(2017) Yuan Gao et al.   Science China-Chemistry

Suzuki–Miyaura cross-coupling of amides and esters at room temperature: correlation with barriers to rotation around C–N and C–O bonds

(2017) Peng Lei et al.   Chemical Science

Zn-Catalyzed tert-Butyl Nicotinate-Directed Amide Cleavage as a Biomimic of Metallo-Exopeptidase Activity

(2017) Clarence C. D. Wybon et al.   ACS Catalysis

Nickel-Catalyzed Reductive Transamidation of Secondary Amides with Nitroarenes

(2017) Chi Wai Cheung et al.   ACS Catalysis

General Method for the Suzuki–Miyaura Cross-Coupling of Amides Using Commercially Available, Air- and Moisture-Stable Palladium/NHC (NHC = N-Heterocyclic Carbene) Complexes

(2017) Peng Lei et al.   ACS Catalysis

Breaking Amides using Nickel Catalysis

(2017) Jacob E. Dander et al.   ACS Catalysis

Synthesis of Biaryls through Nickel-Catalyzed Suzuki-Miyaura Coupling of Amides by Carbon-Nitrogen Bond Cleavage

(2016) Shicheng Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dinuclear PdI complexes with bridging allyl and related ligands

(2016) Nilay Hazari et al.   CHEMICAL SOCIETY REVIEWS

Making the Least Reactive Electrophile the First in Class: Domino Electrophilic Activation of Amides

(2016) Daniel Kaiser et al.   JOURNAL OF ORGANIC CHEMISTRY

Rhodium-Catalyzed C–H Bond Functionalization with Amides by Double C–H/C–N Bond Activation

(2016) Guangrong Meng et al.   ORGANIC LETTERS

SambVca 2. A Web Tool for Analyzing Catalytic Pockets with Topographic Steric Maps

(2016) Laura Falivene et al.   ORGANOMETALLICS

Cross-Coupling of Amides by N–C Bond Activation

(2016) Michal Szostak et al.   SYNLETT

Palladium-Catalyzed Suzuki–Miyaura Cross-Coupling of Amides via Site-Selective N–C Bond Cleavage by Cooperative Catalysis

(2016) Guangrong Meng et al.   ACS Catalysis

Nickel-Catalyzed Deamidative Step-Down Reduction of Amides to Aromatic Hydrocarbons

(2016) Aniruddha Dey et al.   ACS Catalysis

Strong Bonds Made Weak: Towards the General Utility of Amides as Synthetic Modules

(2015) Stefan A. Ruider et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

General Olefin Synthesis by the Palladium-Catalyzed Heck Reaction of Amides: Sterically Controlled Chemoselective NC Activation

(2015) Guangrong Meng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Half-sandwich nickel(II) complexes bearing 1,3-di(cycloalkyl)imidazol-2-ylidene ligands

(2015) Johnathon Yau et al.   Beilstein Journal of Organic Chemistry

An efficient computational model to predict protonation at the amide nitrogen and reactivity along the C–N rotational pathway

(2015) Roman Szostak et al.   CHEMICAL COMMUNICATIONS

Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?

(2015) Dean G. Brown et al.   JOURNAL OF MEDICINAL CHEMISTRY

Conversion of amides to esters by the nickel-catalysed activation of amide C–N bonds

(2015) Liana Hie et al.   NATURE

Sterically Controlled Pd-Catalyzed Chemoselective Ketone Synthesis via N–C Cleavage in Twisted Amides

(2015) Guangrong Meng et al.   ORGANIC LETTERS

Reactions of the 21st Century: Two Decades of Innovative Catalyst Design for Palladium-Catalyzed Cross-Couplings

(2015) Peter G. Gildner et al.   ORGANOMETALLICS

Understanding Precatalyst Activation in Cross-Coupling Reactions: Alcohol Facilitated Reduction from Pd(II) to Pd(0) in Precatalysts of the Type (η3-allyl)Pd(L)(Cl) and (η3-indenyl)Pd(L)(Cl)

(2015) Patrick R. Melvin et al.   ACS Catalysis

Design of a Versatile and Improved Precatalyst Scaffold for Palladium-Catalyzed Cross-Coupling: (η3-1-tBu-indenyl)2(μ-Cl)2Pd2

(2015) Patrick R. Melvin et al.   ACS Catalysis

The use of the sterically demanding IPr* and related ligands in catalysis

(2014) Frédéric Izquierdo et al.   CHEMICAL COMMUNICATIONS

Insight into the Efficiency of Cinnamyl-Supported Precatalysts for the Suzuki–Miyaura Reaction: Observation of Pd(I) Dimers with Bridging Allyl Ligands During Catalysis

(2014) Damian P. Hruszkewycz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An overview of N-heterocyclic carbenes

(2014) Matthew N. Hopkinson et al.   NATURE

Effect of 2-Substituents on Allyl-Supported Precatalysts for the Suzuki–Miyaura Reaction: Relating Catalytic Efficiency to the Stability of Palladium(I) Bridging Allyl Dimers

(2014) Damian P. Hruszkewycz et al.   ORGANOMETALLICS

Quantifying and understanding the electronic properties of N-heterocyclic carbenes

(2013) David J. Nelson et al.   CHEMICAL SOCIETY REVIEWS

Direct Room-Temperature Lactonisation of Alcohols and Ethers onto Amides: An “Amide Strategy” for Synthesis

(2013) Viviana Valerio et al.   CHEMISTRY-A EUROPEAN JOURNAL

How does the addition of steric hindrance to a typical N-heterocyclic carbene ligand affect catalytic activity in olefin metathesis?

(2013) Albert Poater et al.   DALTON TRANSACTIONS

Future directions for peptide therapeutics development

(2013) Allan A. Kaspar et al.   DRUG DISCOVERY TODAY

Enantioselective Polymerization of Epoxides Using Biaryl-Linked Bimetallic Cobalt Catalysts: A Mechanistic Study

(2013) Syud M. Ahmed et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Development of Bulky Palladium NHC Complexes for the Most-Challenging Cross-Coupling Reactions

(2012) Cory Valente et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Cross-Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize

(2012) Carin C. C. Johansson Seechurn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Development of Preformed Pd Catalysts for Cross-Coupling Reactions, Beyond the 2010 Nobel Prize

(2012) Hongbo Li et al.   ACS Catalysis

Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals

(2011) Javier Magano et al.   CHEMICAL REVIEWS

N-Heterocyclic carbene (NHC) ligands and palladium in homogeneous cross-coupling catalysis: a perfect union

(2011) George C. Fortman et al.   CHEMICAL SOCIETY REVIEWS

The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

(2011) Stephen D. Roughley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rethinking amide bond synthesis

(2011) Vijaya R. Pattabiraman et al.   NATURE

Percent buried volume for phosphine and N-heterocyclic carbene ligands: steric properties in organometallic chemistry

(2010) Hervé Clavier et al.   CHEMICAL COMMUNICATIONS

A consistent and accurate ab initio parametrization of density functional dispersion correction (DFT-D) for the 94 elements H-Pu

(2010) Stefan Grimme et al.   JOURNAL OF CHEMICAL PHYSICS

Polyamides - Still Strong After Seventy Years

(2010) Keith Marchildon   Macromolecular Reaction Engineering

Recent Applications of Palladium-Catalyzed Coupling Reactions in the Pharmaceutical, Agrochemical, and Fine Chemical Industries

(2009) Christian Torborg et al.   ADVANCED SYNTHESIS & CATALYSIS

N-Heterocyclic Carbenes in Late Transition Metal Catalysis

(2009) Silvia Díez-González et al.   CHEMICAL REVIEWS

SambVca: A Web Application for the Calculation of the Buried Volume of N-Heterocyclic Carbene Ligands

(2009) Albert Poater et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Well-Defined N-Heterocyclic Carbenes−Palladium(II) Precatalysts for Cross-Coupling Reactions

(2008) Nicolas Marion et al.   ACCOUNTS OF CHEMICAL RESEARCH

Surveying Sterically Demanding N-Heterocyclic Carbene Ligands with Restricted Flexibility for Palladium-catalyzed Cross-Coupling Reactions

(2008) Sebastian Würtz et al.   ACCOUNTS OF CHEMICAL RESEARCH

Understanding the M(NHC) (NHC=N-heterocyclic carbene) bond

(2008) Heiko Jacobsen et al.   COORDINATION CHEMISTRY REVIEWS

Identification and Characterization of a New Family of Catalytically Highly Active Imidazolin-2-ylidenes

(2008) Xinjun Luan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY