An efficient computational model to predict protonation at the amide nitrogen and reactivity along the C–N rotational pathway

The Most Reactive Amide As a Transition-State Mimic For cis–trans Interconversion

(2015) Igor V. Komarov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inside Cover: Increasing the Reactivity of Amides towards Organometallic Reagents: An Overview (Adv. Synth. Catal. 18/2014)

(2014) Vittorio Pace et al.   ADVANCED SYNTHESIS & CATALYSIS

Novel bridgehead bicyclic lactams: (a) Molecules predicted to have O-protonated and N-protonated tautomers of comparable stability; (b) hyperstable lactams and their O-protonated tautomers

(2014) Jessica Morgan et al.   JOURNAL OF CHEMICAL THERMODYNAMICS

Chemistry of Bridged Lactams and Related Heterocycles

(2013) Michal Szostak et al.   CHEMICAL REVIEWS

A New Twist on Amide Solvolysis

(2012) Jeffrey Aubé   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reliable Determination of Amidicity in Acyclic Amides and Lactams

(2012) Stephen A. Glover et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis of (±)-Communesin F via a Cycloaddition with Indol-2-one

(2012) Johannes Belmar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stabilizers cause instability

(2012) Jonathan Clayden   NATURE

1-Azabicyclo[3.3.1]nonan-2-one: Nitrogen Versus Oxygen Protonation

(2011) Brian Sliter et al.   JOURNAL OF ORGANIC CHEMISTRY

A Concise Synthesis of a β-Lactamase Inhibitor

(2011) Ian K. Mangion et al.   ORGANIC LETTERS

Paradigms and paradoxes: O- and N-protonated amides, stabilization energy, and resonance energy

(2011) Jessica Morgan et al.   STRUCTURAL CHEMISTRY

Proximity Effects in Nucleophilic Addition Reactions to Medium-Bridged Twisted Lactams: Remarkably Stable Tetrahedral Intermediates

(2010) Michal Szostak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Water-Stable Helical Structure of Tertiary Amides of Bicyclic β-Amino Acid Bearing 7-Azabicyclo[2.2.1]heptane. Full Control of Amide Cis−Trans Equilibrium by Bridgehead Substitution

(2010) Masahiro Hosoya et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis and Absolute Stereochemical Assignment of (−)-Communesin F

(2010) Zhiwei Zuo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Medium-bridged lactams: a new class of non-planar amides

(2010) Michal Szostak et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and rearrangement of a bridged thioamide

(2009) Michal Szostak et al.   CHEMICAL COMMUNICATIONS

Stability of Medium-Bridged Twisted Amides in Aqueous Solutions

(2009) Michal Szostak et al.   JOURNAL OF ORGANIC CHEMISTRY

Corey−Chaykovsky Epoxidation of Twisted Amides: Synthesis and Reactivity of Bridged Spiro-epoxyamines

(2009) Michal Szostak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quasiplanarity of the Peptide Bond

(2008) Jakub Chalupský et al.   JOURNAL OF PHYSICAL CHEMISTRY A