The Anthelmintic Drug Niclosamide and Its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1
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Title
The Anthelmintic Drug Niclosamide and Its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1
Authors
Keywords
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Journal
CHEMBIOCHEM
Volume 19, Issue 5, Pages 425-429
Publisher
Wiley
Online
2017-12-11
DOI
10.1002/cbic.201700500
References
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Note: Only part of the references are listed.- Kinetin Riboside and Its ProTides Activate the Parkinson’s Disease Associated PTEN-Induced Putative Kinase 1 (PINK1) Independent of Mitochondrial Depolarization
- (2017) Laura Osgerby et al. JOURNAL OF MEDICINAL CHEMISTRY
- Identification of Niclosamide as a Novel Anticancer Agent for Adrenocortical Carcinoma
- (2016) K. Satoh et al. CLINICAL CANCER RESEARCH
- Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation
- (2015) A. Kazlauskaite et al. EMBO REPORTS
- Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
- (2014) Agne Kazlauskaite et al. BIOCHEMICAL JOURNAL
- Membrane depolarization activates the mitochondrial protease OMA1 by stimulating self-cleavage
- (2014) K. Zhang et al. EMBO REPORTS
- PINK1 and Parkin - mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease
- (2014) Agne Kazlauskaite et al. FEBS Journal
- PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
- (2014) Lesley A. Kane et al. JOURNAL OF CELL BIOLOGY
- Ubiquitin is phosphorylated by PINK1 to activate parkin
- (2014) Fumika Koyano et al. NATURE
- Niclosamide ethanolamine–induced mild mitochondrial uncoupling improves diabetic symptoms in mice
- (2014) Hanlin Tao et al. NATURE MEDICINE
- The Anthelmintic Drug Niclosamide Induces Apoptosis, Impairs Metastasis and Reduces Immunosuppressive Cells in Breast Cancer Model
- (2014) Tinghong Ye et al. PLoS One
- A Neo-Substrate that Amplifies Catalytic Activity of Parkinson’s-Disease-Related Kinase PINK1
- (2013) Nicholas T. Hertz et al. CELL
- PINK1 rendered temperature sensitive by disease-associated and engineered mutations
- (2013) D. P. Narendra et al. HUMAN MOLECULAR GENETICS
- Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
- (2013) Shireen A. Sarraf et al. NATURE
- PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
- (2012) C. Kondapalli et al. Open Biology
- Cytometric assessment of mitochondria using fluorescent probes
- (2011) Cécile Cottet-Rousselle et al. CYTOMETRY PART A
- Redeployment-based drug screening identifies the anti-helminthic niclosamide as anti-myeloma therapy that also reduces free light chain production
- (2011) F L Khanim et al. Blood Cancer Journal
- Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: analysis of substrate specificity and impact of mutations
- (2011) H. I. Woodroof et al. Open Biology
- The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases
- (2009) Zhenyu Yue et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- PINK1 controls mitochondrial localization of Parkin through direct phosphorylation
- (2008) Yongsung Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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