The Anthelmintic Drug Niclosamide Induces Apoptosis, Impairs Metastasis and Reduces Immunosuppressive Cells in Breast Cancer Model
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Anthelmintic Drug Niclosamide Induces Apoptosis, Impairs Metastasis and Reduces Immunosuppressive Cells in Breast Cancer Model
Authors
Keywords
Breast cancer, Cancer treatment, Apoptosis, Tumor angiogenesis, Cancer cell migration, Cell staining, Metastasis, Breast tumors
Journal
PLoS One
Volume 9, Issue 1, Pages e85887
Publisher
Public Library of Science (PLoS)
Online
2014-01-09
DOI
10.1371/journal.pone.0085887
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cancer statistics, 2013
- (2013) Rebecca Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Activation of NFkB is a novel mechanism of pro-survival activity of glucocorticoids in breast cancer cells
- (2013) Shagufta Khan et al. CANCER LETTERS
- A Novel Benzothiazole Derivative YLT322 Induces Apoptosis via the Mitochondrial Apoptosis Pathway In Vitro with Anti-Tumor Activity in Solid Malignancies
- (2013) Song Xuejiao et al. PLoS One
- Drug Screening Identifies Niclosamide as an Inhibitor of Breast Cancer Stem-Like Cells
- (2013) Yu-Chi Wang et al. PLoS One
- Inhibition of STAT3 by Niclosamide Synergizes with Erlotinib against Head and Neck Cancer
- (2013) Rui Li et al. PLoS One
- Cucurbitacin E inhibits breast tumor metastasis by suppressing cell migration and invasion
- (2012) Tao Zhang et al. BREAST CANCER RESEARCH AND TREATMENT
- Growth Inhibition of Ovarian Tumor-Initiating Cells by Niclosamide
- (2012) Y.-T. Yo et al. MOLECULAR CANCER THERAPEUTICS
- Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts
- (2012) X. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Niclosamide, an old antihelminthic agent, demonstrates antitumor activity by blocking multiple signaling pathways of cancer stem cells
- (2012) Jing-Xuan Pan et al. Chinese Journal of Cancer
- Breast cancer statistics, 2011
- (2011) Carol DeSantis et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Lipoxin A4 and its analog suppress hepatocellular carcinoma via remodeling tumor microenvironment
- (2011) Hua Hao et al. CANCER LETTERS
- Antihelminth Compound Niclosamide Downregulates Wnt Signaling and Elicits Antitumor Responses in Tumors with Activating APC Mutations
- (2011) T. Osada et al. CANCER RESEARCH
- Novel Effect of Antihelminthic Niclosamide on S100A4-Mediated Metastatic Progression in Colon Cancer
- (2011) U. Sack et al. JNCI-Journal of the National Cancer Institute
- The secreted factors responsible for pre-metastatic niche formation: Old sayings and new thoughts
- (2011) Héctor Peinado et al. SEMINARS IN CANCER BIOLOGY
- Antineoplastic Mechanisms of Niclosamide in Acute Myelogenous Leukemia Stem Cells: Inactivation of the NF- B Pathway and Generation of Reactive Oxygen Species
- (2010) Y. Jin et al. CANCER RESEARCH
- FAK is involved in invasion and metastasis of hepatocellular carcinoma
- (2010) Jing-Song Chen et al. CLINICAL & EXPERIMENTAL METASTASIS
- A Novel Chemoimmunomodulating Property of Docetaxel: Suppression of Myeloid-Derived Suppressor Cells in Tumor Bearers
- (2010) K. N. Kodumudi et al. CLINICAL CANCER RESEARCH
- Identification of Niclosamide as a New Small-Molecule Inhibitor of the STAT3 Signaling Pathway
- (2010) Xiaomei Ren et al. ACS Medicinal Chemistry Letters
- gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis
- (2009) Julia Bollrath et al. CANCER CELL
- Sunitinib Inhibition of Stat3 Induces Renal Cell Carcinoma Tumor Cell Apoptosis and Reduces Immunosuppressive Cells
- (2009) H. Xin et al. CANCER RESEARCH
- Intratumoral Expression of Mature Human Neutrophil Peptide-1 Mediates Antitumor Immunity in Mice
- (2009) Y.-s. Wang et al. CLINICAL CANCER RESEARCH
- Screen for Chemical Modulators of Autophagy Reveals Novel Therapeutic Inhibitors of mTORC1 Signaling
- (2009) Aruna D. Balgi et al. PLoS One
- p21CIP1attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo
- (2009) Manran Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein
- (2008) Pingyan Cheng et al. JOURNAL OF EXPERIMENTAL MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started