Optogenetic Control by Pulsed Illumination

Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2

(2017) Gopal P. Pathak et al.   NUCLEIC ACIDS RESEARCH

Cellular trade-offs and optimal resource allocation during cyanobacterial diurnal growth

(2017) Alexandra-M. Reimers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

At Light Speed: Advances in Optogenetic Systems for Regulating Cell Signaling and Behavior

(2017) Nicole A. Repina et al.   Annual Review of Chemical and Biomolecular Engineering

Dynamic Blue Light-Inducible T7 RNA Polymerases (Opto-T7RNAPs) for Precise Spatiotemporal Gene Expression Control

(2017) Armin Baumschlager et al.   ACS Synthetic Biology

The €100 lab: A 3D-printable open-source platform for fluorescence microscopy, optogenetics, and accurate temperature control during behaviour of zebrafish, Drosophila, and Caenorhabditis elegans

(2017) Andre Maia Chagas et al.   PLOS BIOLOGY

An extraordinary stringent and sensitive light-switchable gene expression system for bacterial cells

(2016) Xianjun Chen et al.   CELL RESEARCH

Optimized second-generation CRY2–CIB dimerizers and photoactivatable Cre recombinase

(2016) Amir Taslimi et al.   Nature Chemical Biology

A bacterial phytochrome-based optogenetic system controllable with near-infrared light

(2016) Andrii A Kaberniuk et al.   NATURE METHODS

Toolbox for Exploring Modular Gene Regulation in Synthetic Biology Training

(2016) Michael S. Magaraci et al.   ACS Synthetic Biology

Engineered Photoactivatable Genetic Switches Based on the Bacterium Phage T7 RNA Polymerase

(2016) Tiyun Han et al.   ACS Synthetic Biology

Repurposing Synechocystis PCC6803 UirS–UirR as a UV-Violet/Green Photoreversible Transcriptional Regulatory Tool in E. coli

(2016) Prabha Ramakrishnan et al.   ACS Synthetic Biology

An open-hardware platform for optogenetics and photobiology

(2016) Karl P. Gerhardt et al.   Scientific Reports

Light-assisted small-molecule screening against protein kinases

(2015) Álvaro Inglés-Prieto et al.   Nature Chemical Biology

Upgrading a microplate reader for photobiology and all-optical experiments

(2015) Florian Richter et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Signal transduction in light–oxygen–voltage receptors lacking the adduct-forming cysteine residue

(2015) Estella F. Yee et al.   Nature Communications

Photochemistry of flavoprotein light sensors

(2014) Karen S Conrad et al.   Nature Chemical Biology

An optogenetic gene expression system with rapid activation and deactivation kinetics

(2014) Laura B Motta-Mena et al.   Nature Chemical Biology

Characterizing bacterial gene circuit dynamics with optically programmed gene expression signals

(2014) Evan J Olson et al.   NATURE METHODS

Plant Flavoprotein Photoreceptors

(2014) J. M. Christie et al.   PLANT AND CELL PHYSIOLOGY

Biophysical, Mutational, and Functional Investigation of the Chromophore-Binding Pocket of Light-Oxygen-Voltage Photoreceptors

(2014) Ralph P. Diensthuber et al.   ACS Synthetic Biology

Phytochrome Cytoplasmic Signaling

(2013) Jon Hughes   Annual Review of Plant Biology

Using Optogenetics to Interrogate the Dynamic Control of Signal Transmission by the Ras/Erk Module

(2013) Jared E. Toettcher et al.   CELL

Microbial and Animal Rhodopsins: Structures, Functions, and Molecular Mechanisms

(2013) Oliver P. Ernst et al.   CHEMICAL REVIEWS

Charting the Signal Trajectory in a Light-Oxygen-Voltage Photoreceptor by Random Mutagenesis and Covariance Analysis

(2013) Tobias Gleichmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Optogenetic protein clustering and signaling activation in mammalian cells

(2013) Lukasz J Bugaj et al.   NATURE METHODS

Multi-chromatic control of mammalian gene expression and signaling

(2013) Konrad Müller et al.   NUCLEIC ACIDS RESEARCH

Fluorescence Imaging-Based High-Throughput Screening of Fast- and Slow-Cycling LOV Proteins

(2013) Fuun Kawano et al.   PLoS One

Full-Length Structure of a Sensor Histidine Kinase Pinpoints Coaxial Coiled Coils as Signal Transducers and Modulators

(2013) Ralph P. Diensthuber et al.   STRUCTURE

Engineering Escherichia coli for Light-Activated Cytolysis of Mammalian Cells

(2013) Michael S. Magaraci et al.   ACS Synthetic Biology

Evolution of Two-Component Signal Transduction Systems

(2012) Emily J. Capra et al.   Annual Review of Microbiology

From Dusk till Dawn: One-Plasmid Systems for Light-Regulated Gene Expression

(2012) Robert Ohlendorf et al.   JOURNAL OF MOLECULAR BIOLOGY

Spatiotemporal control of gene expression by a light-switchable transgene system

(2012) Xue Wang et al.   NATURE METHODS

Light-based feedback for controlling intracellular signaling dynamics

(2011) Jared E Toettcher et al.   NATURE METHODS

Structure and Function of Plant Photoreceptors

(2010) Andreas Möglich et al.   Annual Review of Plant Biology

Multichromatic Control of Gene Expression in Escherichia coli

(2010) Jeffrey J. Tabor et al.   JOURNAL OF MOLECULAR BIOLOGY

Optogenetics

(2010) Karl Deisseroth   NATURE METHODS

Algal Sensory Photoreceptors

(2008) Peter Hegemann   Annual Review of Plant Biology

In Vivo Generation of Flavoproteins with Modified Cofactors

(2008) Tilo Mathes et al.   JOURNAL OF MOLECULAR BIOLOGY

Design and Signaling Mechanism of Light-Regulated Histidine Kinases

(2008) Andreas Möglich et al.   JOURNAL OF MOLECULAR BIOLOGY

A noncytotoxic DsRed variant for whole-cell labeling

(2008) Rita L Strack et al.   NATURE METHODS