Light-assisted small-molecule screening against protein kinases

Upgrading a microplate reader for photobiology and all-optical experiments

(2015) Florian Richter et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Tivozanib: Status of Development

(2015) Muhammad Omer Jamil et al.   Current Oncology Reports

Spatio-temporally precise activation of engineered receptor tyrosine kinases by light

(2014) M. Grusch et al.   EMBO JOURNAL

Characterizing bacterial gene circuit dynamics with optically programmed gene expression signals

(2014) Evan J Olson et al.   NATURE METHODS

Illuminating cell signalling with optogenetic tools

(2014) Doug Tischer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Using Optogenetics to Interrogate the Dynamic Control of Signal Transmission by the Ras/Erk Module

(2013) Jared E. Toettcher et al.   CELL

Visible-Light Photoredox Catalysis

(2012) Jun Xuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

RET, ROS1 and ALK fusions in lung cancer

(2012) Kengo Takeuchi et al.   NATURE MEDICINE

The Development and Application of Optogenetics

(2011) Lief Fenno et al.   Annual Review of Neuroscience

Optical Control of Neuronal Activity

(2010) Stephanie Szobota et al.   Annual Review of Biophysics

Search and clustering orders of magnitude faster than BLAST

(2010) Robert C. Edgar   BIOINFORMATICS

Function of activation loop tyrosine phosphorylation in the mechanism of c-Kit auto-activation and its implication in sunitinib resistance

(2010) J. P. DiNitto et al.   JOURNAL OF BIOCHEMISTRY

A Differential Drug Screen for Compounds That Select Against Antibiotic Resistance

(2010) Remy Chait et al.   PLoS One

Far-red fluorescent tags for protein imaging in living tissues

(2009) Dmitry Shcherbo et al.   BIOCHEMICAL JOURNAL

High-Throughput Screening To Identify Inhibitors Which Stabilize Inactive Kinase Conformations in p38α

(2009) Jeffrey R. Simard et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Pfam protein families database

(2009) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH