Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2

Optimized second-generation CRY2–CIB dimerizers and photoactivatable Cre recombinase

(2016) Amir Taslimi et al.   Nature Chemical Biology

An open-hardware platform for optogenetics and photobiology

(2016) Karl P. Gerhardt et al.   Scientific Reports

CRISPR-Cas9-based Photoactivatable Transcription System

(2015) Yuta Nihongaki et al.   CHEMISTRY & BIOLOGY

A light-inducible CRISPR-Cas9 system for control of endogenous gene activation

(2015) Lauren R Polstein et al.   Nature Chemical Biology

Red Light-Regulated Reversible Nuclear Localization of Proteins in Mammalian Cells and Zebrafish

(2015) Hannes M. Beyer et al.   ACS Synthetic Biology

Optogenetic Control of Gene Expression in Drosophila

(2015) Yick-Bun Chan et al.   PLoS One

An optogenetic gene expression system with rapid activation and deactivation kinetics

(2014) Laura B Motta-Mena et al.   Nature Chemical Biology

Reversible protein inactivation by optogenetic trapping in cells

(2014) Sangkyu Lee et al.   NATURE METHODS

An optimized optogenetic clustering tool for probing protein interaction and function

(2014) Amir Taslimi et al.   Nature Communications

Benchmarking of Optical Dimerizer Systems

(2014) Gopal P. Pathak et al.   ACS Synthetic Biology

General Method for Regulating Protein Stability with Light

(2013) Kimberly M. Bonger et al.   ACS Chemical Biology

CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

(2013) Luke A. Gilbert et al.   CELL

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

(2013) Albert W Cheng et al.   CELL RESEARCH

Formation ofArabidopsisCryptochrome 2 Photobodies in Mammalian Nuclei

(2013) Irem Ozkan-Dagliyan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Optogenetic protein clustering and signaling activation in mammalian cells

(2013) Lukasz J Bugaj et al.   NATURE METHODS

RNA-guided gene activation by CRISPR-Cas9–based transcription factors

(2013) Pablo Perez-Pinera et al.   NATURE METHODS

CRISPR RNA–guided activation of endogenous human genes

(2013) Morgan L Maeder et al.   NATURE METHODS

A red/far-red light-responsive bi-stable toggle switch to control gene expression in mammalian cells

(2013) Konrad Müller et al.   NUCLEIC ACIDS RESEARCH

Multi-chromatic control of mammalian gene expression and signaling

(2013) Konrad Müller et al.   NUCLEIC ACIDS RESEARCH

Ultraviolet-B-mediated induction of protein–protein interactions in mammalian cells

(2013) Remco P. Crefcoeur et al.   Nature Communications

Light-Inducible Spatiotemporal Control of Gene Activation by Customizable Zinc Finger Transcription Factors

(2012) Lauren R. Polstein et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Light-mediated control of DNA transcription in yeast

(2012) Robert M. Hughes et al.   METHODS

Spatiotemporal control of gene expression by a light-switchable transgene system

(2012) Xue Wang et al.   NATURE METHODS

Optogenetic Control of Transcription in Zebrafish

(2012) Hongtao Liu et al.   PLoS One

Rapid blue-light–mediated induction of protein interactions in living cells

(2010) Matthew J Kennedy et al.   NATURE METHODS

Adaptation of GAL4 activators for GAL4 enhancer trapping in zebrafish

(2009) Eri Ogura et al.   DEVELOPMENTAL DYNAMICS

Induction of protein-protein interactions in live cells using light

(2009) Masayuki Yazawa et al.   NATURE BIOTECHNOLOGY

Formation of Nuclear Bodies of Arabidopsis CRY2 in Response to Blue Light Is Associated with Its Blue Light-Dependent Degradation

(2009) X. Yu et al.   PLANT CELL

Genetic dissection of neural circuits by Tol2 transposon-mediated Gal4 gene and enhancer trapping in zebrafish

(2008) K. Asakawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Photoexcited CRY2 Interacts with CIB1 to Regulate Transcription and Floral Initiation in Arabidopsis

(2008) H. Liu et al.   SCIENCE