Boosting phagocytosis and anti-inflammatory phenotype in microglia mediates neuroprotection by PPARγ agonist MDG548 in Parkinson's disease models

Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers

(2018) Michael J Curtis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Autophagy and Microglia: Novel Partners in Neurodegeneration and Aging

(2017) Ainhoa Plaza-Zabala et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY

(2017) Simon D Harding et al.   NUCLEIC ACIDS RESEARCH

Microglial phenotypes in Parkinson’s disease and animal models of the disease

(2017) Valerie Joers et al.   PROGRESS IN NEUROBIOLOGY

Targeting Microglial Activation States as a Therapeutic Avenue in Parkinson’s Disease

(2017) Sudhakar R. Subramaniam et al.   Frontiers in Aging Neuroscience

Genetic and Transcriptomic Profiles of Inflammation in Neurodegenerative Diseases: Alzheimer, Parkinson, Creutzfeldt-Jakob and Tauopathies

(2016) Irene López González et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CD68/macrosialin: not just a histochemical marker

(2016) Dimitry A Chistiakov et al.   LABORATORY INVESTIGATION

CpG-ODN promotes phagocytosis and autophagy through JNK/P38 signal pathway in Staphylococcus aureus-stimulated macrophage

(2016) Hui-Mei Wu et al.   LIFE SCIENCES

Pioglitazone ameliorates the phenotype of a novel Parkinson’s disease mouse model by reducing neuroinflammation

(2016) Milena Pinto et al.   Molecular Neurodegeneration

TAM receptors regulate multiple features of microglial physiology

(2016) Lawrence Fourgeaud et al.   NATURE

PPARγ-induced upregulation of CD36 enhances hematoma resolution and attenuates long-term neurological deficits after germinal matrix hemorrhage in neonatal rats

(2016) Jerry J. Flores et al.   NEUROBIOLOGY OF DISEASE

Immunomodulatory Role of PPAR-γ in Alveolar Macrophages

(2016) Raju C. Reddy   JOURNAL OF INVESTIGATIVE MEDICINE

Parkinsonian toxin-induced oxidative stress inhibits basal autophagy in astrocytes via NQO2/quinone oxidoreductase 2: Implications for neuroprotection

(2015) Elzbieta Janda et al.   Autophagy

Implementing guidelines on reporting research using animals (ARRIVE etc.): new requirements for publication in BJP

(2015) John C McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Nuclear Receptors License Phagocytosis by Trem2+ Myeloid Cells in Mouse Models of Alzheimer's Disease

(2015) J. C. Savage et al.   JOURNAL OF NEUROSCIENCE

Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases

(2015) Yu Tang et al.   MOLECULAR NEUROBIOLOGY

Neuroprotective and anti-inflammatory properties of a novel non-thiazolidinedione PPARγ agonist in vitro and in MPTP-treated mice

(2015) D. Lecca et al.   NEUROSCIENCE

PPARγand the Innate Immune System Mediate the Resolution of Inflammation

(2015) Amanda Croasdell et al.   PPAR Research

Peripheral Biomarkers of Parkinson’s Disease Progression and Pioglitazone Effects

(2015) David K. Simon et al.   Journal of Parkinsons Disease

Pleiotropic Role of PPARγin Intracerebral Hemorrhage: An Intricate System Involving Nrf2, RXR, and NF-κB

(2014) Xiu-Rong Zhao et al.   CNS Neuroscience & Therapeutics

Thiazolidinediones under preclinical and early clinical development for the treatment of Parkinson’s disease

(2014) Anna R Carta et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-γ agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease

(2014) Augusta Pisanu et al.   NEUROBIOLOGY OF DISEASE

Nuclear receptors in neurodegenerative diseases

(2014) Rebecca Skerrett et al.   NEUROBIOLOGY OF DISEASE

Transcriptional Control of Macrophage Polarization

(2013) Derin Tugal et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

PPAR-γ: Therapeutic Prospects in Parkinson's Disease

(2013) Anna R. Carta   CURRENT DRUG TARGETS

Persistent phagocytic characteristics of microglia in the substantia nigra of long-term Parkinsonian macaques

(2013) Carlos Barcia et al.   JOURNAL OF NEUROIMMUNOLOGY

Microglial Beclin 1 Regulates Retromer Trafficking and Phagocytosis and Is Impaired in Alzheimer’s Disease

(2013) Kurt M. Lucin et al.   NEURON

Elevated Alpha-Synuclein Impairs Innate Immune Cell Function and Provides a Potential Peripheral Biomarker for Parkinson's Disease

(2013) Shyra J. Gardai et al.   PLoS One

Parkinson's disease in the nuclear age of neuroinflammation

(2013) Yvonne M. Nolan et al.   TRENDS IN MOLECULAR MEDICINE

PPARγ ligand treatment inhibits cardiac inflammatory mediators induced by infection with different lethality strains of Trypanosoma cruzi

(2012) Federico Penas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Brain-resident microglia predominate over infiltrating myeloid cells in activation, phagocytosis and interaction with T-lymphocytes in the MPTP mouse model of Parkinson disease

(2012) Candan Depboylu et al.   EXPERIMENTAL NEUROLOGY

Integrated Virtual Screening for the Identification of Novel and Selective Peroxisome Proliferator-Activated Receptor (PPAR) Scaffolds

(2012) Daniel K. Nevin et al.   JOURNAL OF MEDICINAL CHEMISTRY

PPAR /RXR -Induced and CD36-Mediated Microglial Amyloid-  Phagocytosis Results in Cognitive Improvement in Amyloid Precursor Protein/Presenilin 1 Mice

(2012) M. Yamanaka et al.   JOURNAL OF NEUROSCIENCE

Defective Autophagy in Parkinson’s Disease: Role of Oxidative Stress

(2012) Elzbieta Janda et al.   MOLECULAR NEUROBIOLOGY

Nuclear Hormone Receptors Enable Macrophages and Dendritic Cells to Sense Their Lipid Environment and Shape Their Immune Response

(2012) Laszlo Nagy et al.   PHYSIOLOGICAL REVIEWS

Alternative Macrophage Activation and Metabolism

(2011) Justin I. Odegaard et al.   Annual Review of Pathology-Mechanisms of Disease

PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation

(2011) Tamas Varga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Nuclear receptors as therapeutic targets for Alzheimer's disease

(2011) Shweta Mandrekar-Colucci et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Deletion of the murine scavenger receptor CD68

(2011) Li Song et al.   JOURNAL OF LIPID RESEARCH

The PPAR-γ agonist pioglitazone modulates inflammation and induces neuroprotection in parkinsonian monkeys

(2011) Christine R Swanson et al.   Journal of Neuroinflammation

Docosahexaenoic acid modulates inflammatory and antineurogenic functions of activated microglial cells

(2011) Maria Antonietta Ajmone-Cat et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Rosiglitazone decreases peroxisome proliferator receptor-gamma levels in microglia and inhibits TNF-alpha production: new evidences on neuroprotection in a progressive Parkinson's disease model

(2011) A.R. Carta et al.   NEUROSCIENCE

STAT6 Transcription Factor Is a Facilitator of the Nuclear Receptor PPARγ-Regulated Gene Expression in Macrophages and Dendritic Cells

(2010) Attila Szanto et al.   IMMUNITY

PPARγ agonist pioglitazone inhibits microglia inflammation by blocking p38 mitogen-activated protein kinase signaling pathways

(2010) Huoyan Ji et al.   INFLAMMATION RESEARCH

Microglial activation depends on beta-amyloid conformation: role of the formylpeptide receptor 2

(2010) Tony Heurtaux et al.   JOURNAL OF NEUROCHEMISTRY

Microglia Acquire Distinct Activation Profiles Depending on the Degree of α-Synuclein Neuropathology in a rAAV Based Model of Parkinson's Disease

(2010) Vanesa Sanchez-Guajardo et al.   PLoS One

PPAR-gamma-mediated neuroprotection in a chronic mouse model of Parkinson’s disease

(2009) Nicoletta Schintu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Characterization of the microglial phenotype under specific pro-inflammatory and anti-inflammatory conditions: Effects of oligomeric and fibrillar amyloid-β

(2009) Alessandro Michelucci et al.   JOURNAL OF NEUROIMMUNOLOGY

Progressive Dopaminergic Degeneration in the Chronic MPTPp Mouse Model of Parkinson’s Disease

(2009) Nicoletta Schintu et al.   NEUROTOXICITY RESEARCH

Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor  B

(2009) C. Porta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted Overexpression of Human α-Synuclein Triggers Microglial Activation and an Adaptive Immune Response in a Mouse Model of Parkinson Disease

(2008) Shaji Theodore et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY