TAM receptors regulate multiple features of microglial physiology

The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity

(2015) Jonathan J Miner et al.   NATURE MEDICINE

Cell type– and brain region–resolved mouse brain proteome

(2015) Kirti Sharma et al.   NATURE NEUROSCIENCE

Mer receptor tyrosine kinase mediates both tethering and phagocytosis of apoptotic cells

(2015) I Dransfield et al.   Cell Death & Disease

Mertk Deficiency Affects Macrophage Directional Migration via Disruption of Cytoskeletal Organization

(2015) Yong Tang et al.   PLoS One

Diversification of TAM receptor tyrosine kinase function

(2014) Anna Zagórska et al.   NATURE IMMUNOLOGY

Microglial phagocytosis of live neurons

(2014) Guy C. Brown et al.   NATURE REVIEWS NEUROSCIENCE

Stepwise Recruitment of Transcellular and Paracellular Pathways Underlies Blood-Brain Barrier Breakdown in Stroke

(2014) Daniel Knowland et al.   NEURON

Regulation and Function of Adult Neurogenesis: From Genes to Cognition

(2014) James B. Aimone et al.   PHYSIOLOGICAL REVIEWS

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

Enveloped Viruses Disable Innate Immune Responses in Dendritic Cells by Direct Activation of TAM Receptors

(2013) Suchita Bhattacharyya et al.   Cell Host & Microbe

TAM Receptors Affect Adult Brain Neurogenesis by Negative Regulation of Microglial Cell Activation

(2013) R. Ji et al.   JOURNAL OF IMMUNOLOGY

Structural and molecular interrogation of intact biological systems

(2013) Kwanghun Chung et al.   NATURE

Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways

(2013) Won-Suk Chung et al.   NATURE

Biology of the TAM Receptors

(2013) G. Lemke   Cold Spring Harbor Perspectives in Biology

CSF protein biomarkers predicting longitudinal reduction of CSF β-amyloid42 in cognitively healthy elders

(2013) N Mattsson et al.   Translational Psychiatry

Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer

(2012) Zhenfeng Zhang et al.   NATURE GENETICS

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

(2012) Emmanuel L Gautier et al.   NATURE IMMUNOLOGY

Genetic Dissection of TAM Receptor-Ligand Interaction in Retinal Pigment Epithelial Cell Phagocytosis

(2012) Tal Burstyn-Cohen et al.   NEURON

Microglia Shape Adult Hippocampal Neurogenesis through Apoptosis-Coupled Phagocytosis

(2010) Amanda Sierra et al.   Cell Stem Cell

The myeloid cells of the central nervous system parenchyma

(2010) Richard M. Ransohoff et al.   NATURE

Chronic optical access through a polished and reinforced thinned skull

(2010) Patrick J Drew et al.   NATURE METHODS

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Lack of Protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis

(2009) Tal Burstyn-Cohen et al.   JOURNAL OF CLINICAL INVESTIGATION

A novel method to determine the engulfment of apoptotic cells by macrophages using pHrodo succinimidyl ester

(2009) Michael Miksa et al.   JOURNAL OF IMMUNOLOGICAL METHODS