miR-139-5p inhibits isoproterenol-induced cardiac hypertrophy by targetting c-Jun

IL-18 cleavage triggers cardiac inflammation and fibrosis upon β-adrenergic insult

(2017) Han Xiao et al.   EUROPEAN HEART JOURNAL

Inhibition of NADPH oxidase by apocynin promotes myocardial antioxidant response and prevents isoproterenol-induced myocardial oxidative stress in rats

(2017) Lokman H. Tanriverdi et al.   FREE RADICAL RESEARCH

β-adrenergic Receptor-stimulated Cardiac Myocyte Apoptosis

(2017) Shan Jiang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

β-Adrenergic induced SR Ca 2+ leak is mediated by an Epac-NOS pathway

(2017) Laëtitia Pereira et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Senescence as a novel mechanism involved in β-adrenergic receptor mediated cardiac hypertrophy

(2017) Rongrong Sun et al.   PLoS One

Calmodulin kinase II inhibition limits the pro-arrhythmic Ca2+waves induced by cAMP-phosphodiesterase inhibitors

(2016) Pierre Bobin et al.   CARDIOVASCULAR RESEARCH

Mst1 inhibition rescues β1-adrenergic cardiomyopathy by reducing myocyte necrosis and non-myocyte apoptosis rather than myocyte apoptosis

(2015) Grace J. Lee et al.   BASIC RESEARCH IN CARDIOLOGY

MicroRNA-139-5p regulates C2C12 cell myogenesis through blocking Wnt/β-catenin signaling pathway

(2015) Lin Mi et al.   Biochemistry and Cell Biology

Involvement of aberrant miR-139/Jun feedback loop in human gastric cancer

(2015) Yan Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The loss of MiR-139-5p promotes colitis-associated tumorigenesis by mediating PI3K/AKT/Wnt signaling

(2015) Rurong Mao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Puerarin Suppresses Angiotensin II-Induced Cardiac Hypertrophy by Inhibiting NADPH Oxidase Activation and Oxidative Stress-Triggered AP-1 Signaling Pathways

(2015) Chen Gang et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

MicroRNA-221 inhibits autophagy and promotes heart failure by modulating the p27/CDK2/mTOR axis

(2014) M Su et al.   CELL DEATH AND DIFFERENTIATION

MiR-451 is decreased in hypertrophic cardiomyopathy and regulates autophagy by targeting TSC1

(2014) Lei Song et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Silencing of miR-34a Attenuates Cardiac Dysfunction in a Setting of Moderate, but Not Severe, Hypertrophic Cardiomyopathy

(2014) Bianca C. Bernardo et al.   PLoS One

Inhibition of AP-1 signaling by JDP2 overexpression protects cardiomyocytes against hypertrophy and apoptosis induction

(2013) Christian Hill et al.   CARDIOVASCULAR RESEARCH

Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis

(2012) Laura S. Danielson et al.   FASEB JOURNAL

Polydatin modulates Ca2+ handling, excitation–contraction coupling and β-adrenergic signaling in rat ventricular myocytes

(2012) Jianxin Deng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Hypertrophic cardiomyopathy

(2012) Barry J Maron et al.   LANCET

Ablation of ALCAT1 Mitigates Hypertrophic Cardiomyopathy through Effects on Oxidative Stress and Mitophagy

(2012) X. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

The PTPN11 loss-of-function mutation Q510E-Shp2 causes hypertrophic cardiomyopathy by dysregulating mTOR signaling

(2011) Christine Schramm et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hypertrophic Cardiomyopathy

(2011) Steve R. Ommen   CURRENT PROBLEMS IN CARDIOLOGY

Fasudil hydrochloride hydrate, a Rho-kinase inhibitor, suppresses isoproterenol-induced heart failure in rats via JNK and ERK1/2 pathways

(2011) Na Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

How do MYBPC3 mutations cause hypertrophic cardiomyopathy?

(2011) Steven Marston et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Loss of PI3Kγ Enhances cAMP-Dependent MMP Remodeling of the Myocardial N-Cadherin Adhesion Complexes and Extracellular Matrix in Response to Early Biomechanical Stress

(2010) Danny Guo et al.   CIRCULATION RESEARCH

Cardiac-Specific IGF-1 Receptor Transgenic Expression Protects Against Cardiac Fibrosis and Diastolic Dysfunction in a Mouse Model of Diabetic Cardiomyopathy

(2010) K. Huynh et al.   DIABETES

β-Adrenergic receptor stimulated Ncx1 upregulation is mediated via a CaMKII/AP-1 signaling pathway in adult cardiomyocytes

(2009) Santhosh K. Mani et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY