Senescence as a novel mechanism involved in β-adrenergic receptor mediated cardiac hypertrophy

Protective effect of resveratrol against chronic intermittent hypoxia-induced spatial memory deficits, hippocampal oxidative DNA damage and increased p47Phox NADPH oxidase expression in young rats

(2016) Basel A. Abdel-Wahab et al.   BEHAVIOURAL BRAIN RESEARCH

Distinct changes of myocyte autophagy during myocardial hypertrophy and heart failure: association with oxidative stress

(2016) Bao Li et al.   EXPERIMENTAL PHYSIOLOGY

Autophagy during cardiac remodeling

(2016) Kazuhiko Nishida et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Downregulation of β-Adrenoceptors in Isoproterenol-Induced Cardiac Remodeling through HuR

(2016) Qian Yin et al.   PLoS One

If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice

(2016) Vladimir N. Anisimov et al.   Aging-US

This old heart: Cardiac aging and autophagy

(2015) Phyllis-Jean Linton et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4

(2015) C. Kang et al.   SCIENCE

Resveratrol Prevents Oxidative Stress-Induced Senescence and Proliferative Dysfunction by Activating the AMPK-FOXO3 Cascade in Cultured Primary Human Keratinocytes

(2015) Yasuo Ido et al.   PLoS One

Crosstalk between AMPK activation and angiotensin II-induced hypertrophy in cardiomyocytes: the role of mitochondria

(2014) Jessica Soto Hernández et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Resveratrol prevents pathological but not physiological cardiac hypertrophy

(2014) Vernon W. Dolinsky et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Rapamycin Attenuated Cardiac Hypertrophy Induced by Isoproterenol and Maintained Energy Homeostasis via Inhibiting NF-κB Activation

(2014) Xi Chen et al.   MEDIATORS OF INFLAMMATION

Defining the toxicology of aging

(2014) Jessica A. Sorrentino et al.   TRENDS IN MOLECULAR MEDICINE

Senescence marker protein 30 inhibits angiotensin II-induced cardiac hypertrophy and diastolic dysfunction

(2013) Tomofumi Misaka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

miR-200b targets GATA-4 during cell growth and differentiation

(2013) Chun-Xia Yao et al.   RNA Biology

Common genetic variants of the β2-adrenergic receptor affect its translational efficiency and are associated with human longevity

(2012) Ling Zhao et al.   AGING CELL

Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response

(2012) Diana Jurk et al.   AGING CELL

Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice

(2012) Vladimir N. Anisimov et al.   CELL CYCLE

Mammalian heart renewal by pre-existing cardiomyocytes

(2012) Samuel E. Senyo et al.   NATURE

Triterpenoid Dihydro-CDDO-Trifluoroethyl Amide Protects against Maladaptive Cardiac Remodeling and Dysfunction in Mice: A Critical Role of Nrf2

(2012) Yifan Xing et al.   PLoS One

Metformin attenuates pressure overload-induced cardiac hypertrophy via AMPK activation

(2011) Yong-nan Fu et al.   ACTA PHARMACOLOGICA SINICA

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

The tumor suppressor p33ING1bupregulates p16INK4aexpression and induces cellular senescence

(2011) Na Li et al.   FEBS LETTERS

Metformin attenuates ventricular hypertrophy by activating the AMP-activated protein kinase-endothelial nitric oxide synthase pathway in rats

(2010) Cheng-Xi Zhang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

CIB1 is a regulator of pathological cardiac hypertrophy

(2010) Joerg Heineke et al.   NATURE MEDICINE

Suppression of Phosphoinositide 3-Kinase Prevents Cardiac Aging in Mice

(2009) Yasutaka Inuzuka et al.   CIRCULATION

A crucial role for adipose tissue p53 in the regulation of insulin resistance

(2009) Tohru Minamino et al.   NATURE MEDICINE

miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophy

(2009) Z. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for Cardiomyocyte Renewal in Humans

(2009) Olaf Bergmann et al.   SCIENCE

Induction of premature senescence in cardiomyocytes by doxorubicin as a novel mechanism of myocardial damage

(2008) Yasuhiro Maejima et al.   AGING CELL

The Aging Cardiomyocyte: A Mini-Review

(2008) D. Bernhard et al.   GERONTOLOGY