Multi-Invasion-Induced Rearrangements as a Pathway for Physiological and Pathological Recombination

Control of structure-specific endonucleases to maintain genome stability

(2017) Pierre-Marie Dehé et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cytosine deamination and base excision repair cause R-loop–induced CAG repeat fragility and instability inSaccharomyces cerevisiae

(2017) Xiaofeng A. Su et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resolution of single and double Holliday junction recombination intermediates by GEN1

(2017) Rajvee Shah Punatar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A global view of meiotic double-strand break end resection

(2017) Eleni P. Mimitou et al.   SCIENCE

Break-induced replication promotes formation of lethal joint molecules dissolved by Srs2

(2017) Rajula Elango et al.   Nature Communications

Distinct DNA-binding surfaces in the ATPase and linker domains of MutLγ determine its substrate specificities and exert separable functions in meiotic recombination and mismatch repair

(2017) Corentin Claeys Bouuaert et al.   PLoS Genetics

High-resolution mapping of heteroduplex DNA formed during UV-induced and spontaneous mitotic recombination events in yeast

(2017) Yi Yin et al.   eLife

Mechanics and Single-Molecule Interrogation of DNA Recombination

(2016) Jason C. Bell et al.   Annual Review of Biochemistry

The Landscape of Mouse Meiotic Double-Strand Break Formation, Processing, and Repair

(2016) Julian Lange et al.   CELL

Germline Chromothripsis Driven by L1-Mediated Retrotransposition and Alu/Alu Homologous Recombination

(2016) Lusine Nazaryan-Petersen et al.   HUMAN MUTATION

Mechanisms underlying structural variant formation in genomic disorders

(2016) Claudia M. B. Carvalho et al.   NATURE REVIEWS GENETICS

Regulation of Single-Strand Annealing and its Role in Genome Maintenance

(2016) Ragini Bhargava et al.   TRENDS IN GENETICS

High-Resolution Mapping of Homologous Recombination Events in rad3 Hyper-Recombination Mutants in Yeast

(2016) Sabrina L. Andersen et al.   PLoS Genetics

Alu-mediated diverse and complex pathogenic copy-number variants within human chromosome 17 at p13.3

(2015) Shen Gu et al.   HUMAN MOLECULAR GENETICS

Top3-Rmi1 DNA Single-Strand Decatenase Is Integral to the Formation and Resolution of Meiotic Recombination Intermediates

(2015) Hardeep Kaur et al.   MOLECULAR CELL

Pervasive and Essential Roles of the Top3-Rmi1 Decatenase Orchestrate Recombination and Facilitate Chromosome Segregation in Meiosis

(2015) Shangming Tang et al.   MOLECULAR CELL

Recombination, Pairing, and Synapsis of Homologs during Meiosis

(2015) Denise Zickler et al.   Cold Spring Harbor Perspectives in Biology

Small Rad51 and Dmc1 Complexes Often Co-occupy Both Ends of a Meiotic DNA Double Strand Break

(2015) M. Scott Brown et al.   PLoS Genetics

Genetic instability is prevented by Mrc1-dependent spatio-temporal separation of replicative and repair activities of homologous recombination

(2014) Félix Prado   BIOESSAYS

Human endogenous retroviral elements promote genome instability via non-allelic homologous recombination

(2014) Ian M Campbell et al.   BMC BIOLOGY

Template Switching During Break-Induced Replication Is Promoted by the Mph1 Helicase inSaccharomyces cerevisiae

(2014) Anamarija Štafa et al.   GENETICS

Mlh1-Mlh3, a Meiotic Crossover and DNA Mismatch Repair Factor, Is a Msh2-Msh3-stimulated Endonuclease

(2014) Maria V. Rogacheva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TheSaccharomyces cerevisiaeMlh1-Mlh3 Heterodimer Is an Endonuclease That Preferentially Binds to Holliday Junctions

(2014) Lepakshi Ranjha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rad54 Functions as a Heteroduplex DNA Pump Modulated by Its DNA Substrates and Rad51 during D Loop Formation

(2014) William Douglass Wright et al.   MOLECULAR CELL

Mouse tetrad analysis provides insights into recombination mechanisms and hotspot evolutionary dynamics

(2014) Francesca Cole et al.   NATURE GENETICS

Sources of DNA Double-Strand Breaks and Models of Recombinational DNA Repair

(2014) A. Mehta et al.   Cold Spring Harbor Perspectives in Biology

Holliday Junction Resolvases

(2014) H. D. M. Wyatt et al.   Cold Spring Harbor Perspectives in Biology

NAHR-mediated copy-number variants in a clinical population: Mechanistic insights into both genomic disorders and Mendelizing traits

(2013) P. Dittwald et al.   GENOME RESEARCH

Mph1 and Mus81-Mms4 Prevent Aberrant Processing of Mitotic Recombination Intermediates

(2013) Gerard Mazón et al.   MOLECULAR CELL

Migrating bubble during break-induced replication drives conservative DNA synthesis

(2013) Natalie Saini et al.   NATURE

Nucleotide Excision Repair in Eukaryotes

(2013) O. D. Scharer   Cold Spring Harbor Perspectives in Biology

Break-Induced DNA Replication

(2013) R. P. Anand et al.   Cold Spring Harbor Perspectives in Biology

Delineation of Joint Molecule Resolution Pathways in Meiosis Identifies a Crossover-Specific Resolvase

(2012) Kseniya Zakharyevich et al.   CELL

Alu-mediated deletion of SOX10 regulatory elements in Waardenburg syndrome type 4

(2012) Nadége Bondurand et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Identification of recurrent type-2NF1microdeletions reveals a mitotic nonallelic homologous recombination hotspot underlying a human genomic disorder

(2012) Julia Vogt et al.   HUMAN MUTATION

Mus81-Mms4 Functions as a Single Heterodimer To Cleave Nicked Intermediates in Recombinational DNA Repair

(2012) E. K. Schwartz et al.   MOLECULAR AND CELLULAR BIOLOGY

BLM Helicase Ortholog Sgs1 Is a Central Regulator of Meiotic Recombination Intermediate Metabolism

(2012) Arnaud De Muyt et al.   MOLECULAR CELL

Single-molecule imaging of DNA pairing by RecA reveals a three-dimensional homology search

(2012) Anthony L. Forget et al.   NATURE

The Rad1-Rad10 nuclease promotes chromosome translocations between dispersed repeats

(2012) Gerard Mazón et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes

(2011) Erin K. Schwartz et al.   CHROMOSOMA

Genome-Wide Analysis of Heteroduplex DNA in Mismatch Repair–Deficient Yeast Cells Reveals Novel Properties of Meiotic Recombination Pathways

(2011) Emmanuelle Martini et al.   PLoS Genetics

Sister Cohesion and Structural Axis Components Mediate Homolog Bias of Meiotic Recombination

(2010) Keun P. Kim et al.   CELL

Recombination Proteins Mediate Meiotic Spatial Chromosome Organization and Pairing

(2010) Aurora Storlazzi et al.   CELL

Temporally and Biochemically Distinct Activities of Exo1 during Meiosis: Double-Strand Break Resection and Resolution of Double Holliday Junctions

(2010) Kseniya Zakharyevich et al.   MOLECULAR CELL

Double Holliday junctions are intermediates of DNA break repair

(2010) Malgorzata Bzymek et al.   NATURE

PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans

(2010) Ingrid L Berg et al.   NATURE GENETICS

Genome destabilization by homologous recombination in the germ line

(2010) Mariko Sasaki et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PRDM9 Is a Major Determinant of Meiotic Recombination Hotspots in Humans and Mice

(2010) F. Baudat et al.   SCIENCE

Competitive Repair by Naturally Dispersed Repetitive DNA during Non-Allelic Homologous Recombination

(2010) Margaret L. Hoang et al.   PLoS Genetics

A junction branch point adjacent to a DNA backbone nick directs substrate cleavage by Saccharomyces cerevisiae Mus81-Mms4

(2009) Kirk Tevebaugh Ehmsen et al.   NUCLEIC ACIDS RESEARCH

Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends

(2008) Zhu Zhu et al.   CELL

Sequence Divergence Impedes Crossover More Than Noncrossover Events During Mitotic Gap Repair in Yeast

(2008) C. Welz-Voegele et al.   GENETICS

A Mutation in the Putative MLH3 Endonuclease Domain Confers a Defect in Both Mismatch Repair and Meiosis in Saccharomyces cerevisiae

(2008) K. T. Nishant et al.   GENETICS

Comparative Genomics and Molecular Dynamics of DNA Repeats in Eukaryotes

(2008) G.-F. Richard et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

RecQ Helicase, Sgs1, and XPF Family Endonuclease, Mus81-Mms4, Resolve Aberrant Joint Molecules during Meiotic Recombination

(2008) Steve D. Oh et al.   MOLECULAR CELL

Mus81/Mms4 Endonuclease and Sgs1 Helicase Collaborate to Ensure Proper Recombination Intermediate Metabolism during Meiosis

(2008) Lea Jessop et al.   MOLECULAR CELL

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

(2008) Eleni P. Mimitou et al.   NATURE

Identification of Holliday junction resolvases from humans and yeast

(2008) Stephen C. Y. Ip et al.   NATURE

A common sequence motif associated with recombination hot spots and genome instability in humans

(2008) Simon Myers et al.   NATURE GENETICS

Saccharomyces cerevisiae Mus81-Mms4 is a catalytic, DNA structure-selective endonuclease

(2008) K. T. Ehmsen et al.   NUCLEIC ACIDS RESEARCH

Double-strand breaks associated with repetitive DNA can reshape the genome

(2008) J. L. Argueso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA