Distinct DNA-binding surfaces in the ATPase and linker domains of MutLγ determine its substrate specificities and exert separable functions in meiotic recombination and mismatch repair

Concerted action of the MutLβ heterodimer and Mer3 helicase regulates the global extent of meiotic gene conversion

(2017) Yann Duroc et al.   eLife

The conserved molecular machinery in DNA mismatch repair enzyme structures

(2016) Flora S. Groothuizen et al.   DNA REPAIR

Roles for mismatch repair family proteins in promoting meiotic crossing over

(2016) Carol M. Manhart et al.   DNA REPAIR

A few of our favorite things: Pairing, the bouquet, crossover interference and evolution of meiosis

(2016) Denise Zickler et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Mismatch Repair

(2015) Richard Fishel   JOURNAL OF BIOLOGICAL CHEMISTRY

Top3-Rmi1 DNA Single-Strand Decatenase Is Integral to the Formation and Resolution of Meiotic Recombination Intermediates

(2015) Hardeep Kaur et al.   MOLECULAR CELL

Pervasive and Essential Roles of the Top3-Rmi1 Decatenase Orchestrate Recombination and Facilitate Chromosome Segregation in Meiosis

(2015) Shangming Tang et al.   MOLECULAR CELL

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Insights from a decade of biophysical studies on MutL: Roles in strand discrimination and mismatch removal

(2015) Alba Guarné et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Mlh1-Mlh3, a Meiotic Crossover and DNA Mismatch Repair Factor, Is a Msh2-Msh3-stimulated Endonuclease

(2014) Maria V. Rogacheva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TheSaccharomyces cerevisiaeMlh1-Mlh3 Heterodimer Is an Endonuclease That Preferentially Binds to Holliday Junctions

(2014) Lepakshi Ranjha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism and Regulation of Meiotic Recombination Initiation

(2014) Isabel Lam et al.   Cold Spring Harbor Perspectives in Biology

Structure of the MutLα C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site

(2013) Emeric Gueneau et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genetic Analysis of mlh3 Mutations Reveals Interactions Between Crossover Promoting Factors During Meiosis in Baker’s Yeast

(2013) Megan Sonntag Brown et al.   G3-Genes Genomes Genetics

Delineation of Joint Molecule Resolution Pathways in Meiosis Identifies a Crossover-Specific Resolvase

(2012) Kseniya Zakharyevich et al.   CELL

The Unstructured Linker Arms of Mlh1–Pms1 Are Important for Interactions with DNA during Mismatch Repair

(2012) Aaron J. Plys et al.   JOURNAL OF MOLECULAR BIOLOGY

BLM Helicase Ortholog Sgs1 Is a Central Regulator of Meiotic Recombination Intermediate Metabolism

(2012) Arnaud De Muyt et al.   MOLECULAR CELL

Regulatory Control of the Resolution of DNA Recombination Intermediates during Meiosis and Mitosis

(2011) Joao Matos et al.   CELL

Exploiting Spore-Autonomous Fluorescent Protein Expression to Quantify Meiotic Chromosome Behaviors inSaccharomyces cerevisiae

(2011) Drew Thacker et al.   GENETICS

The choice in meiosis - defining the factors that influence crossover or non-crossover formation

(2011) J. L. Youds et al.   JOURNAL OF CELL SCIENCE

Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1

(2011) Valerie Garcia et al.   NATURE

Distinct Regulation of Mlh1p Heterodimers in Meiosis and Mitosis in Saccharomyces cerevisiae

(2010) V. E. Cotton et al.   GENETICS

Temporally and Biochemically Distinct Activities of Exo1 during Meiosis: Double-Strand Break Resection and Resolution of Double Holliday Junctions

(2010) Kseniya Zakharyevich et al.   MOLECULAR CELL

Rmi1 stimulates decatenation of double Holliday junctions during dissolution by Sgs1–Top3

(2010) Petr Cejka et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Single-Molecule Analysis Reveals the Kinetics and Physiological Relevance of MutL-ssDNA Binding

(2010) Jonghyun Park et al.   PLoS One

Genetic Analysis of Baker's Yeast Msh4-Msh5 Reveals a Threshold Crossover Level for Meiotic Viability

(2010) K. T. Nishant et al.   PLoS Genetics

Distinct Functions of MLH3 at Recombination Hot Spots in the Mouse

(2008) A. Svetlanov et al.   GENETICS

A Mutation in the Putative MLH3 Endonuclease Domain Confers a Defect in Both Mismatch Repair and Meiosis in Saccharomyces cerevisiae

(2008) K. T. Nishant et al.   GENETICS

Direct Visualization of Asymmetric Adenine Nucleotide-Induced Conformational Changes in MutLα

(2008) Elizabeth J. Sacho et al.   MOLECULAR CELL

Identification of Holliday junction resolvases from humans and yeast

(2008) Stephen C. Y. Ip et al.   NATURE

Crossover assurance and crossover interference are distinctly regulated by the ZMM proteins during yeast meiosis

(2008) Miki Shinohara et al.   NATURE GENETICS