Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes

Identification of KIAA1018/FAN1, a DNA Repair Nuclease Recruited to DNA Damage by Monoubiquitinated FANCD2

(2010) Craig MacKay et al.   CELL

Deficiency of FANCD2-Associated Nuclease KIAA1018/FAN1 Sensitizes Cells to Interstrand Crosslinking Agents

(2010) Katja Kratz et al.   CELL

Mec1/Tel1-dependent phosphorylation of Slx4 stimulates Rad1–Rad10-dependent cleavage of non-homologous DNA tails

(2010) Geraldine W.-L. Toh et al.   DNA REPAIR

Functional overlap between the structure-specific nucleases Yen1 and Mus81-Mms4 for DNA-damage repair in S. cerevisiae

(2010) Miguel G. Blanco et al.   DNA REPAIR

Mechanism of Holliday junction resolution by the human GEN1 protein

(2010) U. Rass et al.   GENES & DEVELOPMENT

Overlapping Roles for Yen1 and Mus81 in Cellular Holliday Junction Processing

(2010) Ye Dee Tay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA Damage Signaling Recruits the Rtt107-Slx4 Scaffolds via Dpb11 to Mediate Replication Stress Response

(2010) Patrice Y. Ohouo et al.   MOLECULAR CELL

A Genetic Screen Identifies FAN1, a Fanconi Anemia-Associated Nuclease Necessary for DNA Interstrand Crosslink Repair

(2010) Agata Smogorzewska et al.   MOLECULAR CELL

Double Holliday junctions are intermediates of DNA break repair

(2010) Malgorzata Bzymek et al.   NATURE

Rmi1 stimulates decatenation of double Holliday junctions during dissolution by Sgs1–Top3

(2010) Petr Cejka et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

FAN1 Acts with FANCI-FANCD2 to Promote DNA Interstrand Cross-Link Repair

(2010) T. Liu et al.   SCIENCE

The Caenorhabditis elegans Homolog of Gen1/Yen1 Resolvases Links DNA Damage Signaling to DNA Double-Strand Break Repair

(2010) Aymeric P. Bailly et al.   PLoS Genetics

A tale of tails: insights into the coordination of 3′ end processing during homologous recombination

(2009) Amy M. Lyndaker et al.   BIOESSAYS

Mammalian BTBD12/SLX4 Assembles A Holliday Junction Resolvase and Is Required for DNA Repair

(2009) Jennifer M. Svendsen et al.   CELL

Human SLX4 Is a Holliday Junction Resolvase Subunit that Binds Multiple DNA Repair/Recombination Endonucleases

(2009) Samira Fekairi et al.   CELL

Cooperativity of Mus81·Mms4 with Rad54 in the Resolution of Recombination and Replication Intermediates

(2009) Petra Matulova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Drosophila MUS312 and the Vertebrate Ortholog BTBD12 Interact with DNA Structure-Specific Endonucleases in DNA Repair and Recombination

(2009) Sabrina L. Andersen et al.   MOLECULAR CELL

Coordination of Structure-Specific Nucleases by Human SLX4/BTBD12 Is Required for DNA Repair

(2009) Ivan M. Muñoz et al.   MOLECULAR CELL

Replication stress induces sister-chromatid bridging at fragile site loci in mitosis

(2009) Kok Lung Chan et al.   NATURE CELL BIOLOGY

A junction branch point adjacent to a DNA backbone nick directs substrate cleavage by Saccharomyces cerevisiae Mus81-Mms4

(2009) Kirk Tevebaugh Ehmsen et al.   NUCLEIC ACIDS RESEARCH

Caenorhabditis elegans HIM-18/SLX-4 Interacts with SLX-1 and XPF-1 and Maintains Genomic Integrity in the Germline by Processing Recombination Intermediates

(2009) Takamune T. Saito et al.   PLoS Genetics

Structural and Functional Relationships of the XPF/MUS81 Family of Proteins

(2008) Alberto Ciccia et al.   Annual Review of Biochemistry

Homologous recombination in DNA repair and DNA damage tolerance

(2008) Xuan Li et al.   CELL RESEARCH

Mus81 is essential for sister chromatid recombination at broken replication forks

(2008) Laura Roseaulin et al.   EMBO JOURNAL

Crystal structure of the Mus81-Eme1 complex

(2008) J. H. Chang et al.   GENES & DEVELOPMENT

Mutants Defective in Rad1-Rad10-Slx4 Exhibit a Unique Pattern of Viability During Mating-Type Switching in Saccharomyces cerevisiae

(2008) A. M. Lyndaker et al.   GENETICS

A Mutation in the Putative MLH3 Endonuclease Domain Confers a Defect in Both Mismatch Repair and Meiosis in Saccharomyces cerevisiae

(2008) K. T. Nishant et al.   GENETICS

ERCC1-XPF Endonuclease Facilitates DNA Double-Strand Break Repair

(2008) A. Ahmad et al.   MOLECULAR AND CELLULAR BIOLOGY

Microarray-Based Genetic Screen Defines SAW1, a Gene Required for Rad1/Rad10-Dependent Processing of Recombination Intermediates

(2008) Fuyang Li et al.   MOLECULAR CELL

Mus81-Dependent Double-Strand DNA Breaks at In Vivo-Generated Cruciform Structures in S. cerevisiae

(2008) Atina G. Coté et al.   MOLECULAR CELL

RecQ Helicase, Sgs1, and XPF Family Endonuclease, Mus81-Mms4, Resolve Aberrant Joint Molecules during Meiotic Recombination

(2008) Steve D. Oh et al.   MOLECULAR CELL

Identification of Holliday junction resolvases from humans and yeast

(2008) Stephen C. Y. Ip et al.   NATURE

Saccharomyces cerevisiae Mus81-Mms4 is a catalytic, DNA structure-selective endonuclease

(2008) K. T. Ehmsen et al.   NUCLEIC ACIDS RESEARCH

Cleavage mechanism of human Mus81-Eme1 acting on Holliday-junction structures

(2008) E. R. Taylor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Rad54 protein stimulates human Mus81-Eme1 endonuclease

(2008) O. M. Mazina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MUS81 Generates a Subset of MLH1-MLH3–Independent Crossovers in Mammalian Meiosis

(2008) J. Kim Holloway et al.   PLoS Genetics

Cleavage of Stalled Forks by Fission Yeast Mus81/Eme1 in Absence of DNA Replication Checkpoint

(2007) Benoît Froget et al.   MOLECULAR BIOLOGY OF THE CELL