- Home
- Publications
- Publication Search
- Publication Details
Title
STAT3 the oncogene - still eluding therapy?
Authors
Keywords
-
Journal
FEBS Journal
Volume 282, Issue 14, Pages 2600-2611
Publisher
Wiley
Online
2015-03-31
DOI
10.1111/febs.13285
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction
- (2016) Marco Demaria et al. Aging-US
- Phase I and biomarker study of OPB-51602, a novel signal transducer and activator of transcription (STAT) 3 inhibitor, in patients with refractory solid malignancies
- (2015) A. L. Wong et al. ANNALS OF ONCOLOGY
- A Novel Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Activities and Exhibits Potent Growth-Suppressive Activity in Human Cancer Cells
- (2015) Li Lin et al. NEOPLASIA
- A Small Molecule Compound Targeting STAT3 DNA-Binding Domain Inhibits Cancer Cell Proliferation, Migration, and Invasion
- (2014) Wei Huang et al. ACS Chemical Biology
- Inhibition of the JAK/STAT pathway with ruxolitinib overcomes cisplatin resistance in non-small-cell lung cancer NSCLC
- (2014) Yuan Hu et al. APOPTOSIS
- Phase 1, open-label, dose-escalation, and pharmacokinetic study of STAT3 inhibitor OPB-31121 in subjects with advanced solid tumors
- (2014) Johanna C. Bendell et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Low PIAS3 Expression in Malignant Mesothelioma Is Associated with Increased STAT3 Activation and Poor Patient Survival
- (2014) S. Dabir et al. CLINICAL CANCER RESEARCH
- Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo
- (2014) Gautam Sethi et al. Molecular Cancer
- Bioinformatic analysis reveals a pattern of STAT3-associated gene expression specific to basal-like breast cancers in human tumors
- (2014) R. W. Tell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MiR-7, Inhibited Indirectly by LincRNA HOTAIR, Directly Inhibits SETDB1 and Reverses the EMT of Breast Cancer Stem Cells by Downregulating the STAT3 Pathway
- (2014) Hongyi Zhang et al. STEM CELLS
- The role of pacritinib in the management of myelofibrosis
- (2014) Vu H Duong et al. Expert Review of Hematology
- Comprehensive meta-analysis of Signal Transducers and Activators of Transcription (STAT) genomic binding patterns discerns cell-specific cis-regulatory modules
- (2013) Keunsoo Kang et al. BMC GENOMICS
- Is there a future for cell-penetrating peptides in oligonucleotide delivery?
- (2013) Soo Hyeon Lee et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- STAT3 inhibition sensitizes colorectal cancer to chemoradiotherapyin vitroandin vivo
- (2013) Melanie Spitzner et al. INTERNATIONAL JOURNAL OF CANCER
- Therapeutic modulators of STAT signalling for human diseases
- (2013) Gabriella Miklossy et al. NATURE REVIEWS DRUG DISCOVERY
- STAT3 suppresses transcription of proapoptotic genes in cancer cells with the involvement of its N-terminal domain
- (2013) Olga A. Timofeeva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- STA-21, a Promising STAT-3 Inhibitor That Reciprocally Regulates Th17 and Treg Cells, Inhibits Osteoclastogenesis in Mice and Humans and Alleviates Autoimmune Inflammation in an Experimental Model of Rheumatoid Arthritis
- (2013) Jin-Sil Park et al. Arthritis & Rheumatology
- Peptides As Therapeutics with Enhanced Bioactivity
- (2012) D. Goodwin et al. CURRENT MEDICINAL CHEMISTRY
- Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements
- (2012) A. Chase et al. HAEMATOLOGICA
- Small Molecule Inhibitors of Signal Transducer and Activator of Transcription 3 (Stat3) Protein
- (2012) Bikash Debnath et al. JOURNAL OF MEDICINAL CHEMISTRY
- Binding Modes of Peptidomimetics Designed to Inhibit STAT3
- (2012) Ankur Dhanik et al. PLoS One
- Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation
- (2012) H. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts
- (2012) X. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- First-in-Human Trial of a STAT3 Decoy Oligonucleotide in Head and Neck Tumors: Implications for Cancer Therapy
- (2012) Malabika Sen et al. Cancer Discovery
- Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas
- (2011) Camilla Pilati et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Fragment-Based Drug Design and Drug Repositioning Using Multiple Ligand Simultaneous Docking (MLSD): Identifying Celecoxib and Template Compounds as Novel Inhibitors of Signal Transducer and Activator of Transcription 3 (STAT3)
- (2011) Huameng Li et al. JOURNAL OF MEDICINAL CHEMISTRY
- Constitutively Active Stat3 Enhances Neu-Mediated Migration and Metastasis in Mammary Tumors via Upregulation of Cten
- (2010) I. Barbieri et al. CANCER RESEARCH
- Stat3 as a Therapeutic Target for the Treatment of Psoriasis: A Clinical Feasibility Study with STA-21, a Stat3 Inhibitor
- (2010) Ken Miyoshi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists
- (2010) Sunil Badve et al. MODERN PATHOLOGY
- The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors
- (2009) Michael Hedvat et al. CANCER CELL
- Palmitoylation of Interferon-α (IFN-α) Receptor Subunit IFNAR1 Is Required for the Activation of Stat1 and Stat2 by IFN-α
- (2009) Julie Claudinon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Crystal structure of unphosphorylated STAT3 core fragment
- (2008) Zhiyong Ren et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Discovery of the catechol structural moiety as a Stat3 SH2 domain inhibitor by virtual screening
- (2008) Wenshan Hao et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Protein tyrosine phosphatases in the JAK/STAT pathway
- (2008) Dan Xu Frontiers in Bioscience-Landmark
- Interleukin-17 Promotes Autoimmunity by Triggering a Positive-Feedback Loop via Interleukin-6 Induction
- (2008) Hideki Ogura et al. IMMUNITY
- Combined Targeting of Epidermal Growth Factor Receptor, Signal Transducer and Activator of Transcription-3, and Bcl-XL Enhances Antitumor Effects in Squamous Cell Carcinoma of the Head and Neck
- (2008) A. L. Boehm et al. MOLECULAR PHARMACOLOGY
- Ups and downs: The STAT1:STAT3 seesaw of Interferon and gp130 receptor signalling
- (2008) Gabriella Regis et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started