STA-21, a Promising STAT-3 Inhibitor That Reciprocally Regulates Th17 and Treg Cells, Inhibits Osteoclastogenesis in Mice and Humans and Alleviates Autoimmune Inflammation in an Experimental Model of Rheumatoid Arthritis

TWEAK Promotes Osteoclastogenesis in Rheumatoid Arthritis

(2013) Jin-Sil Park et al.   AMERICAN JOURNAL OF PATHOLOGY

Targeting kinases: a new approach to treating inflammatory rheumatic diseases

(2013) David L Simmons   CURRENT OPINION IN PHARMACOLOGY

In vitro and in vivo analysis of a JAK inhibitor in rheumatoid arthritis

(2012) Y Tanaka et al.   ANNALS OF THE RHEUMATIC DISEASES

p53 Controls Autoimmune Arthritis via STAT-Mediated Regulation of the Th17 Cell/Treg Cell Balance in Mice

(2012) Jin-Sil Park et al.   ARTHRITIS AND RHEUMATISM

Retinoic Acid Attenuates Rheumatoid Inflammation in Mice

(2012) S.-K. Kwok et al.   JOURNAL OF IMMUNOLOGY

Grape-Seed Proanthocyanidin Extract as Suppressors of Bone Destruction in Inflammatory Autoimmune Arthritis

(2012) Jin-Sil Park et al.   PLoS One

Osteoimmunology: cytokines and the skeletal system

(2011) Seoung-Hoon Lee et al.   BMB Reports

IL-1  and TNF -initiated IL-6-STAT3 pathway is critical in mediating inflammatory cytokines and RANKL expression in inflammatory arthritis

(2011) T. Mori et al.   INTERNATIONAL IMMUNOLOGY

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

(2011) Xiang-Ping Yang et al.   NATURE IMMUNOLOGY

A Four-Step Model for the IL-6 Amplifier, a Regulator of Chronic Inflammations in Tissue-Specific MHC Class II-Associated Autoimmune Diseases

(2011) Masaaki Murakami et al.   Frontiers in Immunology

Diverse Targets of the Transcription Factor STAT3 Contribute to T Cell Pathogenicity and Homeostasis

(2010) Lydia Durant et al.   IMMUNITY

The yin and yang of regulatory T cells and inflammation in RA

(2010) Clare A. Notley et al.   Nature Reviews Rheumatology

Breaking old paradigms: Th17 cells in autoimmune arthritis

(2009) Ariana Peck et al.   CLINICAL IMMUNOLOGY

Regulatory T cells: how do they suppress immune responses?

(2009) S. Sakaguchi et al.   INTERNATIONAL IMMUNOLOGY

Differentiation and function of pro-inflammatory Th17 cells

(2009) Chen Dong   MICROBES AND INFECTION

The role of interleukin-17 in the pathogenesis of rheumatoid arthritis

(2009) Sarah L. Gaffen   Current Rheumatology Reports

Osteoimmunology: Interactions of the Bone and Immune System

(2008) Joseph Lorenzo et al.   ENDOCRINE REVIEWS

Th17 cells in human disease

(2008) Laura A. Tesmer et al.   IMMUNOLOGICAL REVIEWS