Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts

Potent and Selective Phosphopeptide Mimetic Prodrugs Targeted to the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 3

(2011) Pijus K. Mandal et al.   JOURNAL OF MEDICINAL CHEMISTRY

A novel small-molecule disrupts Stat3 SH2 domain–phosphotyrosine interactions and Stat3-dependent tumor processes

(2010) Xiaolei Zhang et al.   BIOCHEMICAL PHARMACOLOGY

Novel STAT3 Phosphorylation Inhibitors Exhibit Potent Growth-Suppressive Activity in Pancreatic and Breast Cancer Cells

(2010) L. Lin et al.   CANCER RESEARCH

KLF8 promotes human breast cancer cell invasion and metastasis by transcriptional activation of MMP9

(2010) X Wang et al.   ONCOGENE

Structure-Based Design of Conformationally Constrained, Cell-Permeable STAT3 Inhibitors

(2010) Jianyong Chen et al.   ACS Medicinal Chemistry Letters

Type 1 plasminogen activator inhibitor (PAI-1) in clear cell renal cell carcinoma (CCRCC) and its impact on angiogenesis, progression and patient survival after radical nephrectomy

(2010) Dragomir P Zubac et al.   BMC Urology

Do serum biomarkers really measure breast cancer?

(2009) Jonathan L Jesneck et al.   BMC CANCER

Persistently Activated Stat3 Maintains Constitutive NF-κB Activity in Tumors

(2009) Heehyoung Lee et al.   CANCER CELL

Dangerous liaisons: STAT3 and NF-κB collaboration and crosstalk in cancer

(2009) Sergei I. Grivennikov et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Structure−Affinity Relationships of Glutamine Mimics Incorporated into Phosphopeptides Targeted to the SH2 Domain of Signal Transducer and Activator of Transcription 3

(2009) Pijus K. Mandal et al.   JOURNAL OF MEDICINAL CHEMISTRY

Molecular Approaches towards the Inhibition of the Signal Transducer and Activator of Transcription 3 (Stat3) Protein

(2008) Steven Fletcher et al.   ChemMedChem

Targeting STAT3 in cancer: how successful are we?

(2008) Peibin Yue et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Activation of KLF8 Transcription by Focal Adhesion Kinase in Human Ovarian Epithelial and Cancer Cells

(2008) Xianhui Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY