Revisiting the stress paradigm for silica nanoparticles: decoupling of the anti-oxidative defense, pro-inflammatory response and cytotoxicity

Autophagy induced by silica nanoparticles protects RAW264.7 macrophages from cell death

(2017) Clarissa Marquardt et al.   TOXICOLOGY

Toxicity of wood smoke particles in human A549 lung epithelial cells: the role of PAHs, soot and zinc

(2016) Marco Dilger et al.   ARCHIVES OF TOXICOLOGY

The safety of nanostructured synthetic amorphous silica (SAS) as a food additive (E 551)

(2016) Claudia Fruijtier-Pölloth   ARCHIVES OF TOXICOLOGY

Protein bio-corona: critical issue in immune nanotoxicology

(2016) Monica Neagu et al.   ARCHIVES OF TOXICOLOGY

Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use

(2016) Jing Sun et al.   Science Signaling

An in vitro alveolar macrophage assay for predicting the short-term inhalation toxicity of nanomaterials

(2016) Martin Wiemann et al.   JOURNAL OF NANOBIOTECHNOLOGY

Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use

(2016) Jing Sun et al.   Science Signaling

Towards understanding of nanoparticle–protein corona

(2015) Cuicui Ge et al.   ARCHIVES OF TOXICOLOGY

In vitro and in vivo genotoxicity investigations of differently sized amorphous SiO2 nanomaterials

(2015) Elena Maser et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Cryptic Epitopes of Albumin Determine Mononuclear Phagocyte System Clearance of Nanomaterials

(2014) Gysell M. Mortimer et al.   ACS Nano

PEGylation of ORMOSIL nanoparticles differently modulates the in vitro toxicity toward human lung cells

(2014) Francesca Moret et al.   ARCHIVES OF TOXICOLOGY

Manufactured nanomaterials: categorization and approaches to hazard assessment

(2014) Thomas Gebel et al.   ARCHIVES OF TOXICOLOGY

A strategy for grouping of nanomaterials based on key physico-chemical descriptors as a basis for safer-by-design NMs

(2014) Iseult Lynch et al.   Nano Today

The protein corona protects against size- and dose-dependent toxicity of amorphous silica nanoparticles

(2014) Dominic Docter et al.   Beilstein Journal of Nanotechnology

Synthesis and Biological Response of Size-Specific, Monodisperse Drug–Silica Nanoconjugates

(2012) Li Tang et al.   ACS Nano

Microsomal Glutathione Transferase 1 Protects Against Toxicity Induced by Silica Nanoparticles but Not by Zinc Oxide Nanoparticles

(2012) Jingwen Shi et al.   ACS Nano

Effects of the Presence or Absence of a Protein Corona on Silica Nanoparticle Uptake and Impact on Cells

(2012) Anna Lesniak et al.   ACS Nano

Suppression of nanosilica particle-induced inflammation by surface modification of the particles

(2012) Tomohiro Morishige et al.   ARCHIVES OF TOXICOLOGY

Safety assessment of nanomaterials: Implications for nanomedicine

(2012) Andreas M. Nyström et al.   JOURNAL OF CONTROLLED RELEASE

Screening of different metal oxide nanoparticles reveals selective toxicity and inflammatory potential of silica nanoparticles in lung epithelial cells and macrophages

(2012) A. Panas et al.   Nanotoxicology

In vitrotoxicity of amorphous silica nanoparticles in human colon carcinoma cells

(2012) Helge Gehrke et al.   Nanotoxicology

Mechanized Silica Nanoparticles: A New Frontier in Theranostic Nanomedicine

(2011) Michael W. Ambrogio et al.   ACCOUNTS OF CHEMICAL RESEARCH

Uptake and intracellular localization of submicron and nano-sized SiO2 particles in HeLa cells

(2011) Marco Al-Rawi et al.   ARCHIVES OF TOXICOLOGY

Role and interaction of p53, BAX and the stress-activated protein kinases p38 and JNK in benzo(a)pyrene-diolepoxide induced apoptosis in human colon carcinoma cells

(2011) Julia Donauer et al.   ARCHIVES OF TOXICOLOGY

The comparative effects of mesoporous silica nanoparticles and colloidal silica on inflammation and apoptosis

(2011) Soyoung Lee et al.   BIOMATERIALS

Oxygen-dependent regulation of nitric oxide production by inducible nitric oxide synthase

(2011) Mary A. Robinson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of the arachidonic acid mobilization in macrophages by combustion-derived particles

(2011) Susanne Fritsch-Decker et al.   Particle and Fibre Toxicology

Evaluation of apoptosis induced by nanoparticles and fine particles in RAW 264.7 macrophages: Facts and artefacts

(2011) Verena Wilhelmi et al.   TOXICOLOGY IN VITRO

Identification of serum proteins bound to industrial nanomaterials

(2011) Hermelindis Ruh et al.   TOXICOLOGY LETTERS

Decoding Cell Death Signals in Inflammation and Immunity

(2010) Laurence Zitvogel et al.   CELL

Cellular recognition and trafficking of amorphous silica nanoparticles by macrophage scavenger receptor A

(2010) Galya A. Orr et al.   Nanotoxicology

Targeting innate immunity protein kinase signalling in inflammation

(2009) Matthias Gaestel et al.   NATURE REVIEWS DRUG DISCOVERY

Influence of aryl hydrocarbon- (Ah) receptor and genotoxins on DNA repair gene expression and cell survival of mouse hepatoma cells

(2009) Ilona Schreck et al.   TOXICOLOGY

Supreme EnLIGHTenment: Damage Recognition and Signaling in the Mammalian UV Response

(2008) Peter Herrlich et al.   MOLECULAR CELL