Manufactured nanomaterials: categorization and approaches to hazard assessment

Molecular toxicity mechanism of nanosilver

(2014) Danielle McShan et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

ITS-NANO - Prioritising nanosafety research to develop a stakeholder driven intelligent testing strategy

(2014) Vicki Stone et al.   Particle and Fibre Toxicology

Cytotoxic evaluation of nanostructured zinc oxide (ZnO) thin films and leachates

(2014) Peter E. Petrochenko et al.   TOXICOLOGY IN VITRO

Pulmonary toxicity of carbon nanotubes and asbestos — Similarities and differences

(2013) Ken Donaldson et al.   ADVANCED DRUG DELIVERY REVIEWS

Nanotoxicity: challenging the myth of nano-specific toxicity

(2013) Ken Donaldson et al.   CURRENT OPINION IN BIOTECHNOLOGY

Mechanistic Heteroaggregation of Gold Nanoparticles in a Wide Range of Solution Chemistry

(2013) A. R. M. Nabiul Afrooz et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Cellular uptake of nanoparticles as determined by particle properties, experimental conditions, and cell type

(2013) Katja Kettler et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Comparative in Vivo Assessment of Some Adverse Bioeffects of Equidimensional Gold and Silver Nanoparticles and the Attenuation of Nanosilver’s Effects with a Complex of Innocuous Bioprotectors

(2013) Boris Katsnelson et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A framework for grouping nanoparticles based on their measurable characteristics

(2013) Christie Sayes et al.   International Journal of Nanomedicine

Cytotoxicity and genotoxicity assessment of silver nanoparticles in mouse

(2013) Yan Li et al.   Nanotoxicology

Concern-driven integrated approaches to nanomaterial testing and assessment – report of the NanoSafety Cluster Working Group 10

(2013) Agnes G. Oomen et al.   Nanotoxicology

Mechanisms of genotoxicity. A review ofin vitroandin vivostudies with engineered nanoparticles

(2013) Zuzana Magdolenova et al.   Nanotoxicology

Comparative absorption, distribution, and excretion of titanium dioxide and zinc oxide nanoparticles after repeated oral administration

(2013) Wan-Seob Cho et al.   Particle and Fibre Toxicology

Titanium dioxide nanoparticles: a review of current toxicological data

(2013) Hongbo Shi et al.   Particle and Fibre Toxicology

Genotoxicity of silver and titanium dioxide nanoparticles in bone marrow cells of rats in vivo

(2013) Małgorzata M. Dobrzyńska et al.   TOXICOLOGY

Nanomaterial Toxicity Testing in the 21st Century: Use of a Predictive Toxicological Approach and High-Throughput Screening

(2012) Andre Nel et al.   ACCOUNTS OF CHEMICAL RESEARCH

Distribution, Elimination, and Toxicity of Silver Nanoparticles and Silver Ions in Rats after 28-Day Oral Exposure

(2012) Meike van der Zande et al.   ACS Nano

Recent developments in nanotoxicology

(2012) H. M. Bolt et al.   ARCHIVES OF TOXICOLOGY

Genotoxicity investigations on nanomaterials

(2012) Franz Oesch et al.   ARCHIVES OF TOXICOLOGY

Toxico-/biokinetics of nanomaterials

(2012) Robert Landsiedel et al.   ARCHIVES OF TOXICOLOGY

Change in agglomeration status and toxicokinetic fate of various nanoparticlesin vivofollowing lung exposure in rats

(2012) Otto Creutzenberg et al.   INHALATION TOXICOLOGY

Time-to-tumor dose threshold analysis for intratracheal particle instillation-induced lung tumors in a large carcinogenicity study

(2012) Markus Roller   INTERNATIONAL JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH

Metal nanoparticle-induced micronuclei and oxidative DNA damage in mice

(2012) Ming-Fen Song et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Evaluation of genotoxic effect of silver nanoparticles (Ag-Nps) in vitro and in vivo

(2012) Priscila Tavares et al.   JOURNAL OF NANOPARTICLE RESEARCH

Development of risk-based nanomaterial groups for occupational exposure control

(2012) E. D. Kuempel et al.   JOURNAL OF NANOPARTICLE RESEARCH

Black sentinel lymph node and ‘scary stickers’

(2012) Arthur S. Yang et al.   Journal of Plastic Reconstructive and Aesthetic Surgery

Polyaspartamide Derivative Nanoparticles with Tunable Surface Charge Achieve Highly Efficient Cellular Uptake and Low Cytotoxicity

(2012) Min Xu et al.   LANGMUIR

Genotoxicity of TiO2 anatase nanoparticles in B6C3F1 male mice evaluated using Pig-a and flow cytometric micronucleus assays

(2012) Rakhshinda Sadiq et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

In vitro and in vivo genotoxicity of silver nanoparticles

(2012) Manosij Ghosh et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Screening of different metal oxide nanoparticles reveals selective toxicity and inflammatory potential of silica nanoparticles in lung epithelial cells and macrophages

(2012) A. Panas et al.   Nanotoxicology

Anin vivoandin vitrotoxicological characterisation of realistic nanoscale CeO2inhalation exposures

(2012) Philip Demokritou et al.   Nanotoxicology

In vitrotoxicity of amorphous silica nanoparticles in human colon carcinoma cells

(2012) Helge Gehrke et al.   Nanotoxicology

Join the dialogue

(2012) Françoise Schrurs et al.   Nature Nanotechnology

The similar neurotoxic effects of nanoparticulate and ionic silver in vivo and in vitro

(2012) Niels Hadrup et al.   NEUROTOXICOLOGY

Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver

(2012) Julie A Bourdon et al.   Particle and Fibre Toxicology

Genotoxicity evaluation of fullerene C60 nanoparticles in a comet assay using lung cells of intratracheally instilled rats

(2012) Makoto Ema et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Physicochemical Characteristics of Nanoparticles Affect Circulation, Biodistribution, Cellular Internalization, and Trafficking

(2012) Xiaopin Duan et al.   Small

Inhalation studies for the safety assessment of nanomaterials: status quo and the way forward

(2012) Robert Landsiedel et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Nanotoxicology: An Interdisciplinary Challenge

(2011) Harald F. Krug et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Uptake and intracellular localization of submicron and nano-sized SiO2 particles in HeLa cells

(2011) Marco Al-Rawi et al.   ARCHIVES OF TOXICOLOGY

The cytotoxicity of cadmium-based quantum dots

(2011) Nan Chen et al.   BIOMATERIALS

Genotoxicity Evaluation of Nanomaterials: DNA Damage, Micronuclei, and 8-Hydroxy-2-deoxyguanosine Induced by Magnetic Doped CdSe Quantum Dots in Male Mice

(2011) W. K. B. Khalil et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Understanding and controlling the interaction of nanomaterials with proteins in a physiological environment

(2011) Carl D. Walkey et al.   CHEMICAL SOCIETY REVIEWS

Nano-Specific Genotoxic Effects

(2011) Hannu Norppa et al.   Journal of Biomedical Nanotechnology

Gene Expression Profiles for Genotoxic Effects of Silica-Free and Silica-Coated Cobalt Ferrite Nanoparticles

(2011) D. W. Hwang et al.   JOURNAL OF NUCLEAR MEDICINE

Microbial status and product labelling of 58 original tattoo inks

(2011) T. Høgsberg et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Aggregation Kinetics and Dissolution of Coated Silver Nanoparticles

(2011) Xuan Li et al.   LANGMUIR

Investigation of genotoxic and cytotoxic effects of micro- and nanosized titanium dioxide in six organs of mice in vivo

(2011) Lyudmila P. Sycheva et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

In vitro genotoxicity testing strategy for nanomaterials and the adaptation of current OECD guidelines

(2011) S.H. Doak et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Investigation on the genotoxicity of different sizes of gold nanoparticles administered to the lungs of rats

(2011) Markus Schulz et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Induction of oxidative stress, DNA damage and apoptosis in mouse liver after sub-acute oral exposure to zinc oxide nanoparticles

(2011) Vyom Sharma et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Genotoxicity of inhaled nanosized TiO2 in mice

(2011) Hanna K. Lindberg et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Carbon nanotube-mediated wireless cell permeabilization: drug and gene uptake

(2011) Vittoria Raffa et al.   Nanomedicine

In vivobiodistribution of nanoparticles

(2011) Joao Paulo Mattos Almeida et al.   Nanomedicine

Inflammatory and genotoxic effects of nanoparticles designed for inclusion in paints and lacquers

(2011) Anne Thoustrup Saber et al.   Nanotoxicology

Pulmonary exposure to carbon black by inhalation or instillation in pregnant mice: Effects on liver DNA strand breaks in dams and offspring

(2011) Petra Jackson et al.   Nanotoxicology

Organ biodistribution, clearance, and genotoxicity of orally administered zinc oxide nanoparticles in mice

(2011) Ching-Hao Li et al.   Nanotoxicology

Silica and titanium dioxide nanoparticles cause pregnancy complications in mice

(2011) Kohei Yamashita et al.   Nature Nanotechnology

In vivo genotoxicity study of titanium dioxide nanoparticles using comet assay following intratracheal instillation in rats

(2011) Masato Naya et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Safety Evaluation of Sunscreen Formulations Containing Titanium Dioxide and Zinc Oxide Nanoparticles in UVB Sunburned Skin: An In Vitro and In Vivo Study

(2011) N. A. Monteiro-Riviere et al.   TOXICOLOGICAL SCIENCES

Identification of serum proteins bound to industrial nanomaterials

(2011) Hermelindis Ruh et al.   TOXICOLOGY LETTERS

Correlating Physico-Chemical with Toxicological Properties of Nanoparticles: The Present and the Future

(2010) Pilar Rivera Gil et al.   ACS Nano

Toxicology of engineered nanomaterials: Focus on biocompatibility, biodistribution and biodegradation

(2010) Andrea Kunzmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Biodistribution and toxicity of engineered gold nanoparticles: a review of in vitro and in vivo studies

(2010) Nikolai Khlebtsov et al.   CHEMICAL SOCIETY REVIEWS

Toxicological evaluation of pH-sensitive nanoparticles of curcumin: Acute, sub-acute and genotoxicity studies

(2010) Prajakta Dandekar et al.   FOOD AND CHEMICAL TOXICOLOGY

Asian dust and titanium dioxide particles–induced inflammation and oxidative DNA damage in C57BL/6 mice

(2010) You Jin Hwang et al.   INHALATION TOXICOLOGY

Gene toxicity studies on titanium dioxide and zinc oxide nanomaterials used for UV-protection in cosmetic formulations

(2010) Robert Landsiedel et al.   Nanotoxicology

Oxidative stress and DNA damage responses in rat and mouse lung to inhaled carbon nanoparticles

(2010) Anton Wessels et al.   Nanotoxicology

Physico-chemical features of engineered nanoparticles relevant to their toxicity

(2010) Bice Fubini et al.   Nanotoxicology

Rapid translocation of nanoparticles from the lung airspaces to the body

(2010) Hak Soo Choi et al.   NATURE BIOTECHNOLOGY

Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation

(2010) Zhou J. Deng et al.   Nature Nanotechnology

Asbestos, carbon nanotubes and the pleural mesothelium: a review and the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma

(2010) Ken Donaldson et al.   Particle and Fibre Toxicology

Oxidative Stress, Inflammation, and DNA Damage in Rats after Intratracheal Instillation or Oral Exposure to Ambient Air and Wood Smoke Particulate Matter

(2010) Pernille Høgh Danielsen et al.   TOXICOLOGICAL SCIENCES

Poorly soluble particulates: Searching for a unifying denominator of nanoparticles and fine particles for DNEL estimation

(2010) Jürgen Pauluhn   TOXICOLOGY

Role of the dissolved zinc ion and reactive oxygen species in cytotoxicity of ZnO nanoparticles

(2010) Wenhua Song et al.   TOXICOLOGY LETTERS

Dose-dependent in-vivo toxicity assessment of silver nanoparticle in Wistar rats

(2010) Dhermendra K Tiwari et al.   TOXICOLOGY MECHANISMS AND METHODS

Influence of anchoring ligands and particle size on the colloidal stability and in vivo biodistribution of polyethylene glycol-coated gold nanoparticles in tumor-xenografted mice

(2009) Guodong Zhang et al.   BIOMATERIALS

NanoGenotoxicology: The DNA damaging potential of engineered nanomaterials

(2009) Neenu Singh et al.   BIOMATERIALS

Titanium Dioxide Nanoparticles Induce DNA Damage and Genetic Instability In vivo in Mice

(2009) B. Trouiller et al.   CANCER RESEARCH

Tattooing of skin results in transportation and light-induced decomposition of tattoo pigments – a first quantification in vivo using a mouse model

(2009) Eva Engel et al.   EXPERIMENTAL DERMATOLOGY

Changing the dose metric for inhalation toxicity studies: Short-term study in rats with engineered aerosolized amorphous silica nanoparticles

(2009) Christie M. Sayes et al.   INHALATION TOXICOLOGY

Carcinogenicity of inhaled nanoparticles

(2009) Markus Roller   INHALATION TOXICOLOGY

Induction of mesothelioma by a single intrascrotal administration of multi-wall carbon nanotube in intact male Fischer 344 rats

(2009) Yoshimitsu Sakamoto et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

In vivo genotoxicity assessment of aluminium oxide nanomaterials in rat peripheral blood cells using the comet assay and micronucleus test

(2009) A. Balasubramanyam et al.   MUTAGENESIS

Genotoxicity of nano/microparticles in in vitro micronuclei, in vivo comet and mutation assay systems

(2009) Yukari Totsuka et al.   Particle and Fibre Toxicology

Stratum Corneum Is an Effective Barrier to TiO2 and ZnO Nanoparticle Percutaneous Absorption

(2009) P. Filipe et al.   SKIN PHARMACOLOGY AND PHYSIOLOGY

Cytotoxicity and Immunological Response of Gold and Silver Nanoparticles of Different Sizes

(2009) Hung-Jen Yen et al.   Small

Pulmonary Toxicity and Fate of Agglomerated 10 and 40 nm Aluminum Oxyhydroxides following 4-Week Inhalation Exposure of Rats: Toxic Effects are Determined by Agglomerated, not Primary Particle Size

(2009) Jürgen Pauluhn   TOXICOLOGICAL SCIENCES

Inhalation Toxicity of Multiwall Carbon Nanotubes in Rats Exposed for 3 Months

(2009) Lan Ma-Hock et al.   TOXICOLOGICAL SCIENCES

Safety assessment of personal care products/cosmetics and their ingredients

(2009) Gerhard J. Nohynek et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

In vitro and in vivo genotoxicity tests on fullerene C60 nanoparticles

(2009) Naohide Shinohara et al.   TOXICOLOGY LETTERS

Particle size-dependent organ distribution of gold nanoparticles after intravenous administration

(2008) Wim H. De Jong et al.   BIOMATERIALS

Clastogenic and aneugenic effects of multi-wall carbon nanotubes in epithelial cells

(2008) Julie Muller et al.   CARCINOGENESIS

Supported gold nanoparticles as catalysts for organic reactions

(2008) Avelino Corma et al.   CHEMICAL SOCIETY REVIEWS

In vitro permeation of gold nanoparticles through rat skin and rat intestine: Effect of particle size

(2008) Ganeshchandra Sonavane et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Oxidatively Damaged DNA in Rats Exposed by Oral Gavage to C 60 Fullerenes and Single-Walled Carbon Nanotubes

(2008) Janne K. Folkmann et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Twenty-Eight-Day Oral Toxicity, Genotoxicity, and Gender-Related Tissue Distribution of Silver Nanoparticles in Sprague-Dawley Rats

(2008) Yong Soon Kim et al.   INHALATION TOXICOLOGY

Delayed presentation of tattoo lymphadenopathy mimicking malignant melanoma lymphadenopathy

(2008) C. Bordea et al.   Journal of Plastic Reconstructive and Aesthetic Surgery

Induction of mesothelioma in p53+/− mouse by intraperitoneal application of multi-wall carbon nanotube

(2008) Atsuya Takagi et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Nanotechnology, Cosmetics and the Skin: Is There a Health Risk?

(2008) G.J. Nohynek et al.   SKIN PHARMACOLOGY AND PHYSIOLOGY

Subchronic Inhalation Toxicity of Silver Nanoparticles

(2008) Jae Hyuck Sung et al.   TOXICOLOGICAL SCIENCES

Pharmacokinetics of nanomaterials: an overview of carbon nanotubes, fullerenes and quantum dots

(2008) Jim E. Riviere   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

The liver sinusoidal endothelial cell: a cell type of controversial and confusing identity

(2007) Kjetil Elvevold et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Cytotoxicity of Nanoparticles

(2007) Nastassja Lewinski et al.   Small