Protein bio-corona: critical issue in immune nanotoxicology

Emerging aspects of nanotoxicology in health and disease: From agriculture and food sector to cancer therapeutics

(2016) Zoi Piperigkou et al.   FOOD AND CHEMICAL TOXICOLOGY

The impact of multi-walled carbon nanotubes with different amount of metallic impurities on immunometabolic parameters in healthy volunteers

(2016) T.I. Vitkina et al.   FOOD AND CHEMICAL TOXICOLOGY

Biochemical and toxicological evaluation of nano-heparins in cell functional properties, proteasome activation and expression of key matrix molecules

(2016) Zoi Piperigkou et al.   TOXICOLOGY LETTERS

Balancing the effect of corona on therapeutic efficacy and macrophage uptake of lipid nanocapsules

(2015) P. Sánchez-Moreno et al.   BIOMATERIALS

Implications of protein corona on physico-chemical and biological properties of magnetic nanoparticles

(2015) Murali M. Yallapu et al.   BIOMATERIALS

A quantitative binding study of fibrinogen and human serum albumin to metal oxide nanoparticles by surface plasmon resonance

(2015) Pilar Canoa et al.   BIOSENSORS & BIOELECTRONICS

It takes two to tango: Understanding the interactions between engineered nanomaterials and the immune system

(2015) Consol Farrera et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Aggregation Behavior of Some Asymmetric Porphyrins versus Basic Biological Tests Response

(2015) Radu Socoteanu et al.   INTERNATIONAL JOURNAL OF PHOTOENERGY

Computational studies of the binding mechanisms of fullerenes to human serum albumin

(2015) Jinyu Li et al.   JOURNAL OF MOLECULAR MODELING

Stealth Effect of Biomolecular Corona on Nanoparticle Uptake by Immune Cells

(2015) Giulio Caracciolo et al.   LANGMUIR

Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells

(2015) Panagiotis Bouris et al.   MATRIX BIOLOGY

Predicting the impact of biocorona formation kinetics on interspecies extrapolations of nanoparticle biodistribution modeling

(2015) Faryad Darabi Sahneh et al.   Nanomedicine

Exploiting the novel properties of protein coronas: emerging applications in nanomedicine

(2015) Kimberly Hamad-Schifferli   Nanomedicine

Biosafety evaluations of well-dispersed mesoporous silica nanoparticles: towards in vivo-relevant conditions

(2015) Tsang-Pai Liu et al.   Nanoscale

Nanoparticle–Cell Interactions: Molecular Structure of the Protein Corona and Cellular Outcomes

(2014) Candace C. Fleischer et al.   ACCOUNTS OF CHEMICAL RESEARCH

Modulation of Complement Activation and Amplification on Nanoparticle Surfaces by Glycopolymer Conformation and Chemistry

(2014) Kai Yu et al.   ACS Nano

Blood protein coating of gold nanoparticles as potential tool for organ targeting

(2014) Martin Schäffler et al.   BIOMATERIALS

Size and charge of nanoparticles following incubation with human plasma of healthy and pancreatic cancer patients

(2014) Giulio Caracciolo et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Cancer Cell Membrane-Coated Nanoparticles for Anticancer Vaccination and Drug Delivery

(2014) Ronnie H. Fang et al.   NANO LETTERS

Protein corona composition does not accurately predict hematocompatibility of colloidal gold nanoparticles

(2014) Marina A. Dobrovolskaia et al.   Nanomedicine-Nanotechnology Biology and Medicine

Adsorption of Cellular Proteins to Polyelectrolyte-Functionalized Gold Nanorods: A Mechanism for Nanoparticle Regulation of Cell Phenotype?

(2014) Patrick N. Sisco et al.   PLoS One

Formation of a Protein Corona on Silver Nanoparticles Mediates Cellular Toxicity via Scavenger Receptors

(2014) Jonathan H. Shannahan et al.   TOXICOLOGICAL SCIENCES

Personalized protein coronas: a “key” factor at the nanobiointerface

(2014) Mohammad J. Hajipour et al.   Biomaterials Science

The liposome–protein corona in mice and humans and its implications for in vivo delivery

(2014) G. Caracciolo et al.   Journal of Materials Chemistry B

Environmental Health and Safety Considerations for Nanotechnology

(2013) Andre Nel et al.   ACCOUNTS OF CHEMICAL RESEARCH

Temperature: The “Ignored” Factor at the NanoBio Interface

(2013) Morteza Mahmoudi et al.   ACS Nano

When carbon nanotubes encounter the immune system: Desirable and undesirable effects

(2013) Hélène Dumortier   ADVANCED DRUG DELIVERY REVIEWS

Microfluidic Chip with Integrated Electrical Cell-Impedance Sensing for Monitoring Single Cancer Cell Migration in Three-Dimensional Matrixes

(2013) Tien Anh Nguyen et al.   ANALYTICAL CHEMISTRY

In Vivo Targeting of Intratumor Regulatory T Cells Using PEG-Modified Single-Walled Carbon Nanotubes

(2013) Cristiano Sacchetti et al.   BIOCONJUGATE CHEMISTRY

Synthesis and Characterization of Lipid Immuno-Nanocapsules for Directed Drug Delivery: Selective Antitumor Activity against HER2 Positive Breast-Cancer Cells

(2013) Paola Sánchez-Moreno et al.   BIOMACROMOLECULES

Glycosaminoglycans are functional ligands for receptor for advanced glycation end-products in tumors

(2013) Shuji Mizumoto et al.   FEBS Journal

Computational and Experimental Characterizations of Silver Nanoparticle–Apolipoprotein Biocorona

(2013) Rongzhong Li et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Time Evolution of Nanoparticle–Protein Corona in Human Plasma: Relevance for Targeted Drug Delivery

(2013) Ana Lilia Barrán-Berdón et al.   LANGMUIR

Effect of polyethyleneglycol (PEG) chain length on the bio–nano-interactions between PEGylated lipid nanoparticles and biological fluids: from nanostructure to uptake in cancer cells

(2013) Daniela Pozzi et al.   Nanoscale

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Tracking protein corona over time

(2013) Martin Lundqvist   Nature Nanotechnology

Nanoparticle-detained toxins for safe and effective vaccination

(2013) Che-Ming J. Hu et al.   Nature Nanotechnology

Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface

(2013) Anna Salvati et al.   Nature Nanotechnology

Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology

(2013) Stefan Tenzer et al.   Nature Nanotechnology

Immunomodulation and T Helper TH1/TH2 Response Polarization by CeO2 and TiO2 Nanoparticles

(2013) Brian C. Schanen et al.   PLoS One

Dynamics of Nanoparticle-Protein Corona Complex Formation: Analytical Results from Population Balance Equations

(2013) Faryad Darabi Sahneh et al.   PLoS One

Correlating preclinical animal studies and human clinical trials of a multifunctional, polymeric nanoparticle

(2013) S. Eliasof et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bridge over troubled waters: understanding the synthetic and biological identities of engineered nanomaterials

(2013) Bengt Fadeel et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Interaction of nanoparticles with proteins: relation to bio-reactivity of the nanoparticle

(2013) Shruti R Saptarshi et al.   JOURNAL OF NANOBIOTECHNOLOGY

Protein coronas suppress the hemolytic activity of hydrophilic and hydrophobic nanoparticles

(2013) Krishnendu Saha et al.   Materials Horizons

Programmed Cell Death: Molecular Mechanisms and Implications for Safety Assessment of Nanomaterials

(2012) Fernando Torres Andón et al.   ACCOUNTS OF CHEMICAL RESEARCH

Amyloid-Derived Peptide Forms Self-Assembled Monolayers on Gold Nanoparticle with a Curvature-Dependent β-Sheet Structure

(2012) Christopher P. Shaw et al.   ACS Nano

Engineering Nano- and Microparticles to Tune Immunity

(2012) James J. Moon et al.   ADVANCED MATERIALS

Glycosaminoglycans: from “cellular glue” to novel therapeutical agents

(2012) Nikos K Karamanos et al.   CURRENT OPINION IN PHARMACOLOGY

Glycosaminoglycans: key players in cancer cell biology and treatment

(2012) Nikos Afratis et al.   FEBS Journal

Colloidal stability and “in vitro” antitumor targeting ability of lipid nanocapsules coated by folate–chitosan conjugates

(2012) Azahara Rata-Aguilar et al.   JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS

Drug delivery research in the European Union's Seventh Framework Programme for Research

(2012) Heico J. Frima et al.   JOURNAL OF CONTROLLED RELEASE

Safety assessment of nanomaterials: Implications for nanomedicine

(2012) Andreas M. Nyström et al.   JOURNAL OF CONTROLLED RELEASE

Nanoparticle Surface Charge Mediates the Cellular Receptors Used by Protein–Nanoparticle Complexes

(2012) Candace C. Fleischer et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Nanoparticle Hydrophobicity Dictates Immune Response

(2012) Daniel F. Moyano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intravenous Delivery of Hydrophobin-Functionalized Porous Silicon Nanoparticles: Stability, Plasma Protein Adsorption and Biodistribution

(2012) Mirkka Sarparanta et al.   MOLECULAR PHARMACEUTICS

PEGylated PRINT Nanoparticles: The Impact of PEG Density on Protein Binding, Macrophage Association, Biodistribution, and Pharmacokinetics

(2012) Jillian L. Perry et al.   NANO LETTERS

Plasma protein binding of positively and negatively charged polymer-coated gold nanoparticles elicits different biological responses

(2012) Zhou J. Deng et al.   Nanotoxicology

Biomolecular coronas provide the biological identity of nanosized materials

(2012) Marco P. Monopoli et al.   Nature Nanotechnology

Immunotoxicological impact of engineered nanomaterial exposure: mechanisms of immune cell modulation

(2012) Xiaojia Wang et al.   TOXICOLOGY MECHANISMS AND METHODS

Superparamagnetic Iron Oxide Nanoparticles: Promises for Diagnosis and Treatment of Multiple Sclerosis

(2011) Morteza Mahmoudi et al.   ACS Chemical Neuroscience

The Evolution of the Protein Corona around Nanoparticles: A Test Study

(2011) Martin Lundqvist et al.   ACS Nano

Single-Walled Carbon Nanotubes Deliver Peptide Antigen into Dendritic Cells and Enhance IgG Responses to Tumor-Associated Antigens

(2011) Carlos H. Villa et al.   ACS Nano

Protein Corona-Mediated Mitigation of Cytotoxicity of Graphene Oxide

(2011) Wenbing Hu et al.   ACS Nano

Complement activation by carbon nanotubes

(2011) Malgorzata J. Rybak-Smith et al.   ADVANCED DRUG DELIVERY REVIEWS

Complement in health and disease

(2011) Maria V. Carroll et al.   ADVANCED DRUG DELIVERY REVIEWS

Protein−Nanoparticle Interactions: Opportunities and Challenges

(2011) Morteza Mahmoudi et al.   CHEMICAL REVIEWS

Interactions of nanoparticles with plasma proteins: implication on clearance and toxicity of drug delivery systems

(2011) Priya Prakash Karmali et al.   Expert Opinion on Drug Delivery

Immune complement activation is attenuated by surface nanotopography

(2011) Mats Hulander et al.   International Journal of Nanomedicine

Physical−Chemical Aspects of Protein Corona: Relevance toin Vitroandin VivoBiological Impacts of Nanoparticles

(2011) Marco P. Monopoli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake

(2011) Carl D. Walkey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evolution of the Protein Corona of Lipid Gene Vectors as a Function of Plasma Concentration

(2011) Giulio Caracciolo et al.   LANGMUIR

Interaction of nanoparticles with immunocompetent cells: nanosafety considerations

(2011) Diana Boraschi et al.   Nanomedicine

Programming the magnitude and persistence of antibody responses with innate immunity

(2011) Sudhir Pai Kasturi et al.   NATURE

Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses

(2011) James J. Moon et al.   NATURE MATERIALS

Alum's adjuvant action: grease is the word

(2011) M Lamine Mbow et al.   NATURE MEDICINE

Immune attack on nanoparticles

(2011) Robert B. Sim et al.   Nature Nanotechnology

Binding of blood proteins to carbon nanotubes reduces cytotoxicity

(2011) C. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Polymer Architecture Mediates Switching of Complement Activation Pathways at the Nanosphere−Serum Interface: Implications for Stealth Nanoparticle Engineering

(2010) Islam Hamad et al.   ACS Nano

Effects of Cell Culture Media on the Dynamic Formation of Protein−Nanoparticle Complexes and Influence on the Cellular Response

(2010) Gabriele Maiorano et al.   ACS Nano

Close Encounters of the Small Kind: Adverse Effects of Man-Made Materials Interfacing with the Nano-Cosmos of Biological Systems

(2010) Anna A. Shvedova et al.   Annual Review of Pharmacology and Toxicology

Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting

(2010) Chrisostomi Gialeli et al.   FEBS Journal

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

What the Cell “Sees” in Bionanoscience

(2010) Dorota Walczyk et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fullerene–porphyrin nanostructures in photodynamic therapy

(2010) Carolina Constantin et al.   Nanomedicine

Cerium oxide nanoparticle-induced pulmonary inflammation and alveolar macrophage functional change in rats

(2010) Jane Y. Ma et al.   Nanotoxicology

Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation

(2010) Zhou J. Deng et al.   Nature Nanotechnology

Protein–Protein Interactions Essentials: Key Concepts to Building and Analyzing Interactome Networks

(2010) Javier De Las Rivas et al.   PLoS Computational Biology

The Role Radius of Curvature Plays in Thiolated Oligonucleotide Loading on Gold Nanoparticles

(2009) Haley D. Hill et al.   ACS Nano

Interaction of Gold Nanoparticles with Common Human Blood Proteins

(2009) Silvia H. De Paoli Lacerda et al.   ACS Nano

Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy

(2009) Parag Aggarwal et al.   ADVANCED DRUG DELIVERY REVIEWS

Complete high-density lipoproteins in nanoparticle corona

(2009) Erik Hellstrand et al.   FEBS Journal

Nanomedicine: reshaping clinical practice

(2009) B. Fadeel et al.   JOURNAL OF INTERNAL MEDICINE

Safety assessment for nanotechnology and nanomedicine: concepts of nanotoxicology

(2009) G. Oberdörster   JOURNAL OF INTERNAL MEDICINE

Differential plasma protein binding to metal oxide nanoparticles

(2009) Zhou J Deng et al.   NANOTECHNOLOGY

Surface hydrophobin prevents immune recognition of airborne fungal spores

(2009) Vishukumar Aimanianda et al.   NATURE

Materials engineering for immunomodulation

(2009) Jeffrey A. Hubbell et al.   NATURE

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

The influence of protein adsorption on nanoparticle association with cultured endothelial cells

(2008) Morton S. Ehrenberg et al.   BIOMATERIALS

Alum adjuvanticity: Unraveling a century old mystery

(2008) Ennio De Gregorio et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Highly specific inhibition of C1q globular-head binding to human IgG: A novel approach to control and regulate the classical complement pathway using an engineered single chain antibody variable fragment

(2008) Hee Young Hwang et al.   MOLECULAR IMMUNOLOGY

Protein-nanoparticle interactions

(2008) Iseult Lynch et al.   Nano Today

Interaction of colloidal gold nanoparticles with human blood: effects on particle size and analysis of plasma protein binding profiles

(2008) Marina A. Dobrovolskaia et al.   Nanomedicine-Nanotechnology Biology and Medicine

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

(2008) M. Lundqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Albumin-conjugated PEG liposome enhances tumor distribution of liposomal doxorubicin in rats

(2007) J YOKOE et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS