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Title
Emerging drugs for the treatment of knee osteoarthritis
Authors
Keywords
-
Journal
EXPERT OPINION ON EMERGING DRUGS
Volume 20, Issue 3, Pages 361-378
Publisher
Informa Healthcare
Online
2015-04-13
DOI
10.1517/14728214.2015.1037275
References
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Note: Only part of the references are listed.- Lifetime Medical Costs of Knee Osteoarthritis Management in the United States: Impact of Extending Indications for Total Knee Arthroplasty
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