Clinical potential of electroporation for gene therapy and DNA vaccine delivery

Coupling treatment planning with navigation system: a new technological approach in treatment of head and neck tumors by electrochemotherapy

(2015) Ales Groselj et al.   Biomedical Engineering Online

Conceptual and technical aspects of transfection and gene delivery

(2015) Lars Kaestner et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Electrochemotherapy of tumors as in situ vaccination boosted by immunogene electrotransfer

(2015) Gregor Sersa et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of Electroporated HIV DNA with or without Interleukin 12 in Prime-Boost Combinations with an Ad35 HIV Vaccine in Healthy HIV-Seronegative African Adults

(2015) Juliet Mpendo et al.   PLoS One

Electroporation-based applications in biotechnology

(2015) Tadej Kotnik et al.   TRENDS IN BIOTECHNOLOGY

The site of administration influences both the type and the magnitude of the immune response induced by DNA vaccine electroporation

(2015) Gaëlle Vandermeulen et al.   VACCINE

DNA vaccine for cancer immunotherapy

(2015) Benjamin Yang et al.   Human Vaccines & Immunotherapeutics

Electroporation-Based Technologies for Medicine: Principles, Applications, and Challenges

(2014) Martin L. Yarmush et al.   Annual Review of Biomedical Engineering

Atomistic Simulations of Pore Formation and Closure in Lipid Bilayers

(2014) W. F. Drew Bennett et al.   BIOPHYSICAL JOURNAL

A Phase 1 clinical trial of Hantaan virus and Puumala virus M-segment DNA vaccines for haemorrhagic fever with renal syndrome delivered by intramuscular electroporation

(2014) J.W. Hooper et al.   CLINICAL MICROBIOLOGY AND INFECTION

Targeted Expression of Suicide Gene by Tissue-Specific Promoter and MicroRNA Regulation for Cancer Gene Therapy

(2014) Ravikanth Danda et al.   PLoS One

Clearance of persistent HPV infection and cervical lesion by therapeutic DNA vaccine in CIN3 patients

(2014) Tae Jin Kim et al.   Nature Communications

Electrochemotherapy with bleomycin induces hallmarks of immunogenic cell death in murine colon cancer cells

(2014) Christophe Y Calvet et al.   OncoImmunology

Safety and Comparative Immunogenicity of an HIV-1 DNA Vaccine in Combination with Plasmid Interleukin 12 and Impact of Intramuscular Electroporation for Delivery

(2013) Spyros A. Kalams et al.   JOURNAL OF INFECTIOUS DISEASES

Therapeutic DNA Vaccination Using In Vivo Electroporation Followed by Standard of Care Therapy in Patients With Genotype 1 Chronic Hepatitis C

(2013) Ola Weiland et al.   MOLECULAR THERAPY

DNA vaccine coding for the rhesus prostate specific antigen delivered by intradermal electroporation in patients with relapsed prostate cancer

(2013) Fredrik Eriksson et al.   VACCINE

Tolerability of intramuscular and intradermal delivery by CELLECTRA®adaptive constant current electroporation device in healthy volunteers

(2013) Malissa C Diehl et al.   Human Vaccines & Immunotherapeutics

Synthetic DNA Vaccines: Improved Vaccine Potency by Electroporation and Co-Delivered Genetic Adjuvants

(2013) Seleeke Flingai et al.   Frontiers in Immunology

Gene Electrotransfer of Plasmid Antiangiogenic Metargidin Peptide (AMEP) in Disseminated Melanoma: Safety and Efficacy Results of a Phase I First-in-Man Study

(2013) Iben Spanggaard et al.   Human Gene Therapy Clinical Development

Trial watch

(2013) Laura Senovilla et al.   OncoImmunology

Immunologic responses to xenogeneic tyrosinase DNA vaccine administered by electroporation in patients with malignant melanoma

(2013) Jianda Yuan et al.   Journal for ImmunoTherapy of Cancer

Antitumor effectiveness of electrochemotherapy: A systematic review and meta-analysis

(2012) B. Mali et al.   EJSO

Technologies for enhanced efficacy of DNA vaccines

(2012) Fadi Saade et al.   Expert Review of Vaccines

The future of human DNA vaccines

(2012) Lei Li et al.   JOURNAL OF BIOTECHNOLOGY

A pilot randomized controlled trial of dual-plasmid HBV DNA vaccine mediated by in vivo electroporation in chronic hepatitis B patients under lamivudine chemotherapy

(2012) F.-Q. Yang et al.   JOURNAL OF VIRAL HEPATITIS

Immunotherapy Against HPV16/18 Generates Potent TH1 and Cytotoxic Cellular Immune Responses

(2012) M. L. Bagarazzi et al.   Science Translational Medicine

What you always needed to know about electroporation based DNA vaccines

(2012) Anita Gothelf et al.   Human Vaccines & Immunotherapeutics

Efficacy of transgene expression in porcine skin as a function of electrode choice

(2011) Anita Gothelf et al.   BIOELECTROCHEMISTRY

Codon usage: Nature's roadmap to expression and folding of proteins

(2011) Evelina Angov   Biotechnology Journal

CpG DNA as a vaccine adjuvant

(2011) Christian Bode et al.   Expert Review of Vaccines

Electro-gene transfer to skin using a noninvasive multielectrode array

(2011) Siqi Guo et al.   JOURNAL OF CONTROLLED RELEASE

New Generation of Plasmid Backbones Devoid of Antibiotic Resistance Marker for Gene Therapy Trials

(2011) Gaëlle Vandermeulen et al.   MOLECULAR THERAPY

Safety and Tolerability of the Easy Vax™ Clinical Epidermal Electroporation System in Healthy Adults

(2011) Samer S El-Kamary et al.   MOLECULAR THERAPY

In Vivo Electroporation Enhances the Immunogenicity of an HIV-1 DNA Vaccine Candidate in Healthy Volunteers

(2011) Sandhya Vasan et al.   PLoS One

Evaluation of a Novel Non-Penetrating Electrode for Use in DNA Vaccination

(2011) Amy Donate et al.   PLoS One

Gene Electrotransfer to Skin; Review of Existing Literature and Clinical Perspectives

(2010) Anita Gothelf et al.   CURRENT GENE THERAPY

Hollow Microneedle Arrays for Intradermal Drug Delivery and DNA Electroporation

(2010) Liévin Daugimont et al.   JOURNAL OF MEMBRANE BIOLOGY

Induced Transmembrane Voltage and Its Correlation with Electroporation-Mediated Molecular Transport

(2010) Tadej Kotnik et al.   JOURNAL OF MEMBRANE BIOLOGY

Synonymous but not the same: the causes and consequences of codon bias

(2010) Joshua B. Plotkin et al.   NATURE REVIEWS GENETICS

Increased in vivo immunological potency of HB-110, a novel therapeutic HBV DNA vaccine, by electroporation

(2009) Chae Young Kim et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Electrically Mediated Delivery of Plasmid DNA to the Skin, Using a Multielectrode Array

(2009) Richard Heller et al.   HUMAN GENE THERAPY

You're one in a googol: optimizing genes for protein expression

(2009) M. Welch et al.   Journal of the Royal Society Interface

Optimization of Skin Electroporation in Mice to Increase Tolerability of DNA Vaccine Delivery to Patients

(2009) Anna-Karin Roos et al.   MOLECULAR THERAPY

Tolerability of Two Sequential Electroporation Treatments Using MedPulser DNA Delivery System (DDS) in Healthy Adults

(2009) Mark Wallace et al.   MOLECULAR THERAPY

Skin-specific promoters for genetic immunisation by DNA electroporation

(2009) Gaëlle Vandermeulen et al.   VACCINE

Electroporation of skeletal muscle induces danger signal release and antigen-presenting cell recruitment independently of DNA vaccine administration

(2008) Pieranna Chiarella et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Efficiency of High- and Low-Voltage Pulse Combinations for Gene Electrotransfer in Muscle, Liver, Tumor, and Skin

(2008) F.M. André et al.   HUMAN GENE THERAPY

Phase I Trial of Interleukin-12 Plasmid Electroporation in Patients With Metastatic Melanoma

(2008) Adil I. Daud et al.   JOURNAL OF CLINICAL ONCOLOGY

Electrochemotherapy in treatment of tumours

(2007) G. Sersa et al.   EJSO

Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques

(2007) Lauren A. Hirao et al.   VACCINE