A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of Electroporated HIV DNA with or without Interleukin 12 in Prime-Boost Combinations with an Ad35 HIV Vaccine in Healthy HIV-Seronegative African Adults
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Title
A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of Electroporated HIV DNA with or without Interleukin 12 in Prime-Boost Combinations with an Ad35 HIV Vaccine in Healthy HIV-Seronegative African Adults
Authors
Keywords
Enzyme-linked immunoassays, T cells, HIV, Vaccines, Antibodies, Cytotoxic T cells, Vaccination and immunization, Immune response
Journal
PLoS One
Volume 10, Issue 8, Pages e0134287
Publisher
Public Library of Science (PLoS)
Online
2015-08-08
DOI
10.1371/journal.pone.0134287
References
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- (2014) Christine M. Hay et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
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- Broad HIV Epitope Specificity and Viral Inhibition Induced by Multigenic HIV-1 Adenovirus Subtype 35 Vector Vaccine in Healthy Uninfected Adults
- (2014) Jakub Kopycinski et al. PLoS One
- Safety and Comparative Immunogenicity of an HIV-1 DNA Vaccine in Combination with Plasmid Interleukin 12 and Impact of Intramuscular Electroporation for Delivery
- (2013) Spyros A. Kalams et al. JOURNAL OF INFECTIOUS DISEASES
- Synthetic DNA Vaccines: Improved Vaccine Potency by Electroporation and Co-Delivered Genetic Adjuvants
- (2013) Seleeke Flingai et al. Frontiers in Immunology
- The future of human DNA vaccines
- (2012) Lei Li et al. JOURNAL OF BIOTECHNOLOGY
- Antiviral Inhibitory Capacity of CD8+ T cells Predicts the Rate of CD4+ T-Cell Decline in HIV-1 Infection
- (2012) Hongbing Yang et al. JOURNAL OF INFECTIOUS DISEASES
- Safety and Immunogenicity of an HIV-1 Gag DNA Vaccine with or without IL-12 and/or IL-15 Plasmid Cytokine Adjuvant in Healthy, HIV-1 Uninfected Adults
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- A Phase I Double Blind, Placebo-Controlled, Randomized Study of a Multigenic HIV-1 Adenovirus Subtype 35 Vector Vaccine in Healthy Uninfected Adults
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- What you always needed to know about electroporation based DNA vaccines
- (2012) Anita Gothelf et al. Human Vaccines & Immunotherapeutics
- IL-12 DNA as molecular vaccine adjuvant increases the cytotoxic T cell responses and breadth of humoral immune responses in SIV DNA vaccinated macaques
- (2012) Rashmi Jalah et al. Human Vaccines & Immunotherapeutics
- Clinical Applications of DNA Vaccines: Current Progress
- (2011) B. Ferraro et al. CLINICAL INFECTIOUS DISEASES
- Electroporation delivery of DNA vaccines: prospects for success
- (2011) Niranjan Y Sardesai et al. CURRENT OPINION IN IMMUNOLOGY
- In Vivo Electroporation Enhances the Immunogenicity of an HIV-1 DNA Vaccine Candidate in Healthy Volunteers
- (2011) Sandhya Vasan et al. PLoS One
- Cancer Electrogene Therapy with Interleukin-12
- (2010) Maja Cemazar et al. CURRENT GENE THERAPY
- Electroporation for DNA immunization: clinical application
- (2010) Sylvia van Drunen Littel-van den Hurk et al. Expert Review of Vaccines
- A Phase 1/2 Study of a Multiclade HIV‐1 DNA Plasmid Prime and Recombinant Adenovirus Serotype 5 Boost Vaccine in HIV‐Uninfected East Africans (RV 172)
- (2010) Hannah Kibuuka et al. JOURNAL OF INFECTIOUS DISEASES
- Viral Inhibition Assay: A CD8 T Cell Neutralization Assay for Use in Clinical Trials of HIV‐1 Vaccine Candidates
- (2010) Aggeliki Spentzou et al. JOURNAL OF INFECTIOUS DISEASES
- Phenotypic and Functional Profile of HIV-Inhibitory CD8 T Cells Elicited by Natural Infection and Heterologous Prime/Boost Vaccination
- (2010) S. A. Freel et al. JOURNAL OF VIROLOGY
- Comparative Analysis of Immune Responses Induced by Vaccination With SIV Antigens by Recombinant Ad5 Vector or Plasmid DNA in Rhesus Macaques
- (2010) Lauren A Hirao et al. MOLECULAR THERAPY
- Priming Immunization with DNA Augments Immunogenicity of Recombinant Adenoviral Vectors for Both HIV-1 Specific Antibody and T-Cell Responses
- (2010) Richard A. Koup et al. PLoS One
- Safety and Immunogenicity Study of Multiclade HIV-1 Adenoviral Vector Vaccine Alone or as Boost following a Multiclade HIV-1 DNA Vaccine in Africa
- (2010) Walter Jaoko et al. PLoS One
- DNA Vaccination with Electroporation Induces Increased Antibody Responses in Patients with Prostate Cancer
- (2009) Lindsey Low et al. HUMAN GENE THERAPY
- Regulation of interleukin-12/interleukin-23 production and the T-helper 17 response in humans
- (2009) Lyudmila Lyakh et al. IMMUNOLOGICAL REVIEWS
- Heterogeneity in HIV Suppression by CD8 T Cells from HIV Controllers: Association with Gag-Specific CD8 T Cell Responses
- (2009) A. Saez-Cirion et al. JOURNAL OF IMMUNOLOGY
- Concordant Proficiency in Measurement of T-Cell Immunity in Human Immunodeficiency Virus Vaccine Clinical Trials by Peripheral Blood Mononuclear Cell and Enzyme-Linked Immunospot Assays in Laboratories from Three Continents
- (2008) M. J. Boaz et al. Clinical and Vaccine Immunology
- Electrochemotherapy in treatment of tumours
- (2007) G. Sersa et al. EJSO
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