Prolyl hydroxylase inhibitors act as agents to enhance the efficiency of cell therapy
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Title
Prolyl hydroxylase inhibitors act as agents to enhance the efficiency of cell therapy
Authors
Keywords
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Journal
EXPERT OPINION ON BIOLOGICAL THERAPY
Volume 15, Issue 12, Pages 1739-1755
Publisher
Informa Healthcare
Online
2015-09-01
DOI
10.1517/14712598.2015.1084281
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Note: Only part of the references are listed.- Cobalt chloride supplementation induces stem-cell marker expression and inhibits osteoblastic differentiation in human periodontal ligament cells
- (2015) Thanaphum Osathanon et al. ARCHIVES OF ORAL BIOLOGY
- The emerging role of hypoxia-inducible factor-2 involved in chemo/radioresistance in solid tumors
- (2015) Jiuda Zhao et al. CANCER TREATMENT REVIEWS
- Hypoxic Preconditioning of Mesenchymal Stromal Cells Induces Metabolic Changes, Enhances Survival, and Promotes Cell Retention In Vivo
- (2015) Julie Beegle et al. STEM CELLS
- Matrix Metalloproteinase 9 Secreted by Hypoxia Cardiac Fibroblasts Triggers Cardiac Stem Cell Migration In Vitro
- (2015) Qing Gao et al. Stem Cells International
- Cobalt chloride induces neuronal differentiation of human mesenchymal stem cells through upregulation of microRNA-124a
- (2014) Eun Su Jeon et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Hypoxia-inducible factor-2α (HIF-2α), but not HIF-1α, is essential for hypoxic induction of class III β-tubulin expression in human glioblastoma cells
- (2014) Karim Bordji et al. FEBS Journal
- Dimethyloxaloylglycine Improves Angiogenic Activity of Bone Marrow Stromal Cells in the Tissue-Engineered Bone
- (2014) Hao Ding et al. International Journal of Biological Sciences
- Hypoxic Conditioned Medium from Human Amniotic Fluid-Derived Mesenchymal Stem Cells Accelerates Skin Wound Healing through TGF-β/SMAD2 and PI3K/Akt Pathways
- (2014) Eun Jun et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Advancing stem cell therapy from bench to bedside: lessons from drug therapies
- (2014) Thekkeparambil Chandrabose Srijaya et al. Journal of Translational Medicine
- Preconditioning of bone marrow mesenchymal stem cells by prolyl hydroxylase inhibition enhances cell survival and angiogenesis in vitro and after transplantation into the ischemic heart of rats
- (2014) Xian-Bao Liu et al. Stem Cell Research & Therapy
- Stem Cells as New Agents for the Treatment of Infertility: Current and Future Perspectives and Challenges
- (2014) Vladislav Volarevic et al. Biomed Research International
- Delivery of dimethyloxallyl glycine in mesoporous bioactive glass scaffolds to improve angiogenesis and osteogenesis of human bone marrow stromal cells
- (2013) Chengtie Wu et al. Acta Biomaterialia
- Prolyl 4-hydroxylases, master regulators of the hypoxia response
- (2013) J. Myllyharju Acta Physiologica
- Stem Cell-Based Therapy for Ischemic Heart Disease
- (2013) Lien-Cheng Hsiao et al. CELL TRANSPLANTATION
- Prolyl Hydroxylase Domain Protein 2 Silencing Enhances the Survival and Paracrine Function of Transplanted Adipose-Derived Stem Cells in Infarcted Myocardium
- (2013) Wei Eric Wang et al. CIRCULATION RESEARCH
- PHD1 Links Cell-Cycle Progression to Oxygen Sensing through Hydroxylation of the Centrosomal Protein Cep192
- (2013) Sandra C. Moser et al. DEVELOPMENTAL CELL
- Deferoxamine preconditioning potentiates mesenchymal stem cell homingin vitroand in streptozotocin-diabetic rats
- (2013) R Najafi et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Combination of HIF-1α gene transfection and HIF-1-activated bone marrow-derived angiogenic cell infusion improves burn wound healing in aged mice
- (2013) J Du et al. GENE THERAPY
- Sca-1-Positive Cardiac Stem Cell migration in a Cardiac Infarction Model
- (2013) Jingjin Liu et al. INFLAMMATION
- Prolyl 4 Hydroxylase: A Critical Target in the Pathophysiology of Diseases
- (2013) Ravi Kant et al. KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY
- A Novel Prolyl Hydroxylase Inhibitor Protects Against Cell Death After Hypoxia
- (2013) Satoru Kontani et al. NEUROCHEMICAL RESEARCH
- Wound Healing Improvement with PHD-2 Silenced Fibroblasts in Diabetic Mice
- (2013) Xiongliang Zhang et al. PLoS One
- The Contributions of HIF-Target Genes to Tumor Growth in RCC
- (2013) Ting Zhang et al. PLoS One
- HIF-Prolyl Hydroxylase 2 Inhibition Enhances the Efficiency of Mesenchymal Stem Cell-Based Therapies for the Treatment of Critical Limb Ischemia
- (2013) Kiave-Yune HoWangYin et al. STEM CELLS
- Dimethyloxaloylglycine Increases the Bone Healing Capacity of Adipose-Derived Stem Cells by Promoting Osteogenic Differentiation and Angiogenic Potential
- (2013) Hao Ding et al. STEM CELLS AND DEVELOPMENT
- Hypoxic Culture Conditions as a Solution for Mesenchymal Stem Cell Based Regenerative Therapy
- (2013) Nazmul Haque et al. TheScientificWorldJOURNAL
- Hypoxia preconditioned bone marrow mesenchymal stem cells promoted liver regeneration in a rat massive hepatectomy model
- (2013) Jun Yu et al. Stem Cell Research & Therapy
- Catalytic mechanism and substrate specificity of HIF prolyl hydroxylases
- (2012) N. A. Smirnova et al. BIOCHEMISTRY-MOSCOW
- Hypoxic preconditioning enhances the therapeutic potential of the secretome from cultured human mesenchymal stem cells in experimental traumatic brain injury
- (2012) Ching-Ping Chang et al. CLINICAL SCIENCE
- Hypoxia-inducible factor-2a is associated with ABCG2 expression, histology-grade and Ki67 expression in breast invasive ductal carcinoma
- (2012) Lei Xiang et al. Diagnostic Pathology
- Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors
- (2012) Yan Xia et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Expression of Prolyl Hydroxylases (PHDs) Is Selectively Controlled by HIF-1 and HIF-2 Proteins in Nucleus Pulposus Cells of the Intervertebral Disc
- (2012) Nobuyuki Fujita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) Seongyeon Jo et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition: Robust New Target or Another Big Bust for Stroke Therapeutics?
- (2012) Saravanan S Karuppagounder et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response
- (2012) Liang Xie et al. JOURNAL OF CLINICAL INVESTIGATION
- Prolyl Hydroxylase Inhibitors Increase the Production of Vascular Endothelial Growth Factor in Dental Pulp–derived Cells
- (2012) Heinz-Dieter Müller et al. JOURNAL OF ENDODONTICS
- Synthetic hydrogel scaffold is an effective vehicle for delivery of INFUSE (rhBMP2) to critical-sized calvaria bone defects in rats
- (2012) Peter D. Mariner et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- New bone formation in a true bone ceramic scaffold loaded with desferrioxamine in the treatment of segmental bone defect: a preliminary study
- (2012) Weibin Zhang et al. JOURNAL OF ORTHOPAEDIC SCIENCE
- Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial
- (2012) Raj R Makkar et al. LANCET
- The Role of SDF-1-CXCR4/CXCR7 Axis in the Therapeutic Effects of Hypoxia-Preconditioned Mesenchymal Stem Cells for Renal Ischemia/Reperfusion Injury
- (2012) Hongbao Liu et al. PLoS One
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- (2012) Mitsuru Takaku et al. PLoS One
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- (2012) Fengdi Yan et al. PLoS One
- Hypoxia Promotes Osteogenesis but Suppresses Adipogenesis of Human Mesenchymal Stromal Cells in a Hypoxia-Inducible Factor-1 Dependent Manner
- (2012) Markus Wagegg et al. PLoS One
- Passing the baton: the HIF switch
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- HIF-1 versus HIF-2 — Is one more important than the other?
- (2012) Agnieszka Loboda et al. VASCULAR PHARMACOLOGY
- Stem cell technology for neurodegenerative diseases
- (2011) J. Simon Lunn et al. ANNALS OF NEUROLOGY
- Clinical trials for stem cell therapies
- (2011) Alan Trounson et al. BMC Medicine
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- (2011) F. Vegran et al. CANCER RESEARCH
- Culture of human mesenchymal stem cells at low oxygen tension improves growth and genetic stability by activating glycolysis
- (2011) J C Estrada et al. CELL DEATH AND DIFFERENTIATION
- Double Knockdown of Prolyl Hydroxylase and Factor-Inhibiting Hypoxia-Inducible Factor With Nonviral Minicircle Gene Therapy Enhances Stem Cell Mobilization and Angiogenesis After Myocardial Infarction
- (2011) M. Huang et al. CIRCULATION
- Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1
- (2011) Brian Hynes et al. EUROPEAN HEART JOURNAL
- Aging impairs the mobilization and homing of bone marrow-derived angiogenic cells to burn wounds
- (2011) Xianjie Zhang et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Increasing Vascularity to Improve Healing of a Segmental Defect of the Rat Femur
- (2011) Rena Stewart et al. JOURNAL OF ORTHOPAEDIC TRAUMA
- Constitutive HIF-1α Expression Blunts the Beneficial Effects of Cardiosphere-Derived Cell Therapy in the Heart by Altering Paracrine Factor Balance
- (2011) Michael Bonios et al. Journal of Cardiovascular Translational Research
- Evolution of oxygen utilization in multicellular organisms and implications for cell signalling in tissue engineering
- (2011) Katerina Stamati et al. Journal of Tissue Engineering
- Hypoxia. 1. Intracellular sensors for oxygen and oxidative stress: novel therapeutic targets
- (2010) Toshio Miyata et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Paracrine factors released by GATA-4 overexpressed mesenchymal stem cells increase angiogenesis and cell survival
- (2010) Hongxia Li et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Beneficial Effects of Desferrioxamine on Encapsulated Human Islets-In Vitro and In Vivo Study
- (2010) V. Vaithilingam et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Dual control: the HIF-2 regulator
- (2010) T. Lappin BLOOD
- Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche
- (2010) Ahmed Mohyeldin et al. Cell Stem Cell
- Roles of hypoxia-inducible factor-1α (HIF-1α) versus HIF-2α in the survival of hepatocellular tumor spheroids
- (2010) Heidi Menrad et al. HEPATOLOGY
- Chronic Inhibition of Hypoxia-inducible Factor Prolyl 4-hydroxylase Improves Ventricular Performance, Remodeling, and Vascularity After Myocardial Infarction in the Rat
- (2010) Weike Bao et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- The role of HIF prolyl hydroxylases in tumour growth
- (2010) Terhi Jokilehto et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Oxygen Sensing in Drosophila: Multiple Isoforms of the Prolyl Hydroxylase Fatiga Have Different Capacity to Regulate HIFα/Sima
- (2010) Julieta M. Acevedo et al. PLoS One
- Engineering vascularized tissues using natural and synthetic small molecules
- (2010) Lauren S. Sefcik et al. Organogenesis
- Cellular oxygen sensing: Importins and exportins are mediators of intracellular localisation of prolyl-4-hydroxylases PHD1 and PHD2
- (2009) Amrei Steinhoff et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mesenchymal stem cells cultured under hypoxia escape from senescence via down-regulation of p16 and extracellular signal regulated kinase
- (2009) Yonghui Jin et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Hepatocyte Growth Factor or Vascular Endothelial Growth Factor Gene Transfer Maximizes Mesenchymal Stem Cell-Based Myocardial Salvage After Acute Myocardial Infarction
- (2009) T. Deuse et al. CIRCULATION
- Cardiac Progenitor Cells and Biotinylated Insulin-Like Growth Factor-1 Nanofibers Improve Endogenous and Exogenous Myocardial Regeneration After Infarction
- (2009) M. Elena Padin-Iruegas et al. CIRCULATION
- Hypoxia inducible factor-2α: a critical mediator of aggressive tumor phenotypes
- (2009) Guoliang Qing et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Hypoxia induced paclitaxel resistance in human ovarian cancers via hypoxia-inducible factor 1α
- (2009) Lei Huang et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Prolyl hydroxylase inhibitor dimethyloxalylglycine enhances mesenchymal stem cell survival
- (2009) Xian-Bao Liu et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The role of oxygen in regulating neural stem cells in development and disease
- (2009) David M. Panchision JOURNAL OF CELLULAR PHYSIOLOGY
- Role of hypoxia-inducible factor-1α in angiogenic–osteogenic coupling
- (2009) Ryan C. Riddle et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice
- (2009) Xing Shen et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Critical limb ischemia
- (2009) Vinit N. Varu et al. JOURNAL OF VASCULAR SURGERY
- miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche
- (2009) Li-Chun Cheng et al. NATURE NEUROSCIENCE
- Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease
- (2009) Peter Fraisl et al. NATURE REVIEWS DRUG DISCOVERY
- Non-hypoxic Stabilization of Hypoxia-Inducible Factor Alpha (HIF-α): Relevance in Neural Progenitor/Stem Cells
- (2009) Javorina Milosevic et al. NEUROTOXICITY RESEARCH
- Synergistic effect of HIF-1 gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
- (2009) S. Rey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Improving outcome of transplanted mesenchymal stem cells for ischemic heart disease
- (2008) Rui-Zhen Shi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Promotion of osteogenesis through β-catenin signaling by desferrioxamine
- (2008) Zhi-Hu Qu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Transplantation of human neural stem cells protect against ischemia in a preventive mode via hypoxia-inducible factor-1α stabilization in the host brain
- (2008) Kon Chu et al. BRAIN RESEARCH
- Role and regulation of prolyl hydroxylase domain proteins
- (2008) G-H Fong et al. CELL DEATH AND DIFFERENTIATION
- Biology of HIF-1α
- (2008) A Weidemann et al. CELL DEATH AND DIFFERENTIATION
- PHDs overactivation during chronic hypoxia "desensitizes" HIF and protects cells from necrosis
- (2008) A. Ginouves et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activation of the hypoxia-inducible factor-1 pathway accelerates bone regeneration
- (2008) C. Wan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypoxic Preconditioning Results in Increased Motility and Improved Therapeutic Potential of Human Mesenchymal Stem Cells
- (2008) Ivana Rosová et al. STEM CELLS
- Overexpression of Vascular Endothelial Growth Factor In Vitro Using Deferoxamine: A New Drug to Increase Islet Vascularization During Transplantation
- (2008) A. Langlois et al. TRANSPLANTATION PROCEEDINGS
- Prolyl 4-hydroxylase activity-responsive transcription factors: From hydroxylation to gene expression and neuroprotection
- (2007) Ambreena Siddiq Frontiers in Bioscience-Landmark
- No place like home: anatomy and function of the stem cell niche
- (2007) D. Leanne Jones et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A brief definition of regenerative medicine
- (2007) Chris Mason et al. Regenerative Medicine
- Mesenchymal Stem Cells Cooperate with Bone Marrow Cells in Therapy of Diabetes
- (2007) Veronika S. Urbán et al. STEM CELLS
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