Prolyl hydroxylase inhibitors act as agents to enhance the efficiency of cell therapy
出版年份 2015 全文链接
标题
Prolyl hydroxylase inhibitors act as agents to enhance the efficiency of cell therapy
作者
关键词
-
出版物
EXPERT OPINION ON BIOLOGICAL THERAPY
Volume 15, Issue 12, Pages 1739-1755
出版商
Informa Healthcare
发表日期
2015-09-01
DOI
10.1517/14712598.2015.1084281
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Cobalt chloride supplementation induces stem-cell marker expression and inhibits osteoblastic differentiation in human periodontal ligament cells
- (2015) Thanaphum Osathanon et al. ARCHIVES OF ORAL BIOLOGY
- The emerging role of hypoxia-inducible factor-2 involved in chemo/radioresistance in solid tumors
- (2015) Jiuda Zhao et al. CANCER TREATMENT REVIEWS
- Hypoxic Preconditioning of Mesenchymal Stromal Cells Induces Metabolic Changes, Enhances Survival, and Promotes Cell Retention In Vivo
- (2015) Julie Beegle et al. STEM CELLS
- Matrix Metalloproteinase 9 Secreted by Hypoxia Cardiac Fibroblasts Triggers Cardiac Stem Cell Migration In Vitro
- (2015) Qing Gao et al. Stem Cells International
- Cobalt chloride induces neuronal differentiation of human mesenchymal stem cells through upregulation of microRNA-124a
- (2014) Eun Su Jeon et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Hypoxia-inducible factor-2α (HIF-2α), but not HIF-1α, is essential for hypoxic induction of class III β-tubulin expression in human glioblastoma cells
- (2014) Karim Bordji et al. FEBS Journal
- Dimethyloxaloylglycine Improves Angiogenic Activity of Bone Marrow Stromal Cells in the Tissue-Engineered Bone
- (2014) Hao Ding et al. International Journal of Biological Sciences
- Hypoxic Conditioned Medium from Human Amniotic Fluid-Derived Mesenchymal Stem Cells Accelerates Skin Wound Healing through TGF-β/SMAD2 and PI3K/Akt Pathways
- (2014) Eun Jun et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Advancing stem cell therapy from bench to bedside: lessons from drug therapies
- (2014) Thekkeparambil Chandrabose Srijaya et al. Journal of Translational Medicine
- Preconditioning of bone marrow mesenchymal stem cells by prolyl hydroxylase inhibition enhances cell survival and angiogenesis in vitro and after transplantation into the ischemic heart of rats
- (2014) Xian-Bao Liu et al. Stem Cell Research & Therapy
- Stem Cells as New Agents for the Treatment of Infertility: Current and Future Perspectives and Challenges
- (2014) Vladislav Volarevic et al. Biomed Research International
- Delivery of dimethyloxallyl glycine in mesoporous bioactive glass scaffolds to improve angiogenesis and osteogenesis of human bone marrow stromal cells
- (2013) Chengtie Wu et al. Acta Biomaterialia
- Prolyl 4-hydroxylases, master regulators of the hypoxia response
- (2013) J. Myllyharju Acta Physiologica
- Stem Cell-Based Therapy for Ischemic Heart Disease
- (2013) Lien-Cheng Hsiao et al. CELL TRANSPLANTATION
- Prolyl Hydroxylase Domain Protein 2 Silencing Enhances the Survival and Paracrine Function of Transplanted Adipose-Derived Stem Cells in Infarcted Myocardium
- (2013) Wei Eric Wang et al. CIRCULATION RESEARCH
- PHD1 Links Cell-Cycle Progression to Oxygen Sensing through Hydroxylation of the Centrosomal Protein Cep192
- (2013) Sandra C. Moser et al. DEVELOPMENTAL CELL
- Deferoxamine preconditioning potentiates mesenchymal stem cell homingin vitroand in streptozotocin-diabetic rats
- (2013) R Najafi et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Combination of HIF-1α gene transfection and HIF-1-activated bone marrow-derived angiogenic cell infusion improves burn wound healing in aged mice
- (2013) J Du et al. GENE THERAPY
- Sca-1-Positive Cardiac Stem Cell migration in a Cardiac Infarction Model
- (2013) Jingjin Liu et al. INFLAMMATION
- Prolyl 4 Hydroxylase: A Critical Target in the Pathophysiology of Diseases
- (2013) Ravi Kant et al. KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY
- A Novel Prolyl Hydroxylase Inhibitor Protects Against Cell Death After Hypoxia
- (2013) Satoru Kontani et al. NEUROCHEMICAL RESEARCH
- Wound Healing Improvement with PHD-2 Silenced Fibroblasts in Diabetic Mice
- (2013) Xiongliang Zhang et al. PLoS One
- The Contributions of HIF-Target Genes to Tumor Growth in RCC
- (2013) Ting Zhang et al. PLoS One
- HIF-Prolyl Hydroxylase 2 Inhibition Enhances the Efficiency of Mesenchymal Stem Cell-Based Therapies for the Treatment of Critical Limb Ischemia
- (2013) Kiave-Yune HoWangYin et al. STEM CELLS
- Dimethyloxaloylglycine Increases the Bone Healing Capacity of Adipose-Derived Stem Cells by Promoting Osteogenic Differentiation and Angiogenic Potential
- (2013) Hao Ding et al. STEM CELLS AND DEVELOPMENT
- Hypoxic Culture Conditions as a Solution for Mesenchymal Stem Cell Based Regenerative Therapy
- (2013) Nazmul Haque et al. TheScientificWorldJOURNAL
- Hypoxia preconditioned bone marrow mesenchymal stem cells promoted liver regeneration in a rat massive hepatectomy model
- (2013) Jun Yu et al. Stem Cell Research & Therapy
- Catalytic mechanism and substrate specificity of HIF prolyl hydroxylases
- (2012) N. A. Smirnova et al. BIOCHEMISTRY-MOSCOW
- Hypoxic preconditioning enhances the therapeutic potential of the secretome from cultured human mesenchymal stem cells in experimental traumatic brain injury
- (2012) Ching-Ping Chang et al. CLINICAL SCIENCE
- Hypoxia-inducible factor-2a is associated with ABCG2 expression, histology-grade and Ki67 expression in breast invasive ductal carcinoma
- (2012) Lei Xiang et al. Diagnostic Pathology
- Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors
- (2012) Yan Xia et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Expression of Prolyl Hydroxylases (PHDs) Is Selectively Controlled by HIF-1 and HIF-2 Proteins in Nucleus Pulposus Cells of the Intervertebral Disc
- (2012) Nobuyuki Fujita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Effects of recombinant human bone morphogenic protein-2 and human bone marrow-derived stromal cells onin vivobone regeneration of chitosan-poly(ethylene oxide) hydrogel
- (2012) Seongyeon Jo et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition: Robust New Target or Another Big Bust for Stroke Therapeutics?
- (2012) Saravanan S Karuppagounder et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response
- (2012) Liang Xie et al. JOURNAL OF CLINICAL INVESTIGATION
- Prolyl Hydroxylase Inhibitors Increase the Production of Vascular Endothelial Growth Factor in Dental Pulp–derived Cells
- (2012) Heinz-Dieter Müller et al. JOURNAL OF ENDODONTICS
- Synthetic hydrogel scaffold is an effective vehicle for delivery of INFUSE (rhBMP2) to critical-sized calvaria bone defects in rats
- (2012) Peter D. Mariner et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- New bone formation in a true bone ceramic scaffold loaded with desferrioxamine in the treatment of segmental bone defect: a preliminary study
- (2012) Weibin Zhang et al. JOURNAL OF ORTHOPAEDIC SCIENCE
- Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial
- (2012) Raj R Makkar et al. LANCET
- The Role of SDF-1-CXCR4/CXCR7 Axis in the Therapeutic Effects of Hypoxia-Preconditioned Mesenchymal Stem Cells for Renal Ischemia/Reperfusion Injury
- (2012) Hongbao Liu et al. PLoS One
- Systemic Preconditioning by a Prolyl Hydroxylase Inhibitor Promotes Prevention of Skin Flap Necrosis via HIF-1-Induced Bone Marrow-Derived Cells
- (2012) Mitsuru Takaku et al. PLoS One
- Hypoxic Preconditioning Improves Survival of Cardiac Progenitor Cells: Role of Stromal Cell Derived Factor-1α–CXCR4 Axis
- (2012) Fengdi Yan et al. PLoS One
- Hypoxia Promotes Osteogenesis but Suppresses Adipogenesis of Human Mesenchymal Stromal Cells in a Hypoxia-Inducible Factor-1 Dependent Manner
- (2012) Markus Wagegg et al. PLoS One
- Passing the baton: the HIF switch
- (2012) Mei Yee Koh et al. TRENDS IN BIOCHEMICAL SCIENCES
- HIF-1 versus HIF-2 — Is one more important than the other?
- (2012) Agnieszka Loboda et al. VASCULAR PHARMACOLOGY
- Stem cell technology for neurodegenerative diseases
- (2011) J. Simon Lunn et al. ANNALS OF NEUROLOGY
- Clinical trials for stem cell therapies
- (2011) Alan Trounson et al. BMC Medicine
- Lactate Influx through the Endothelial Cell Monocarboxylate Transporter MCT1 Supports an NF- B/IL-8 Pathway that Drives Tumor Angiogenesis
- (2011) F. Vegran et al. CANCER RESEARCH
- Culture of human mesenchymal stem cells at low oxygen tension improves growth and genetic stability by activating glycolysis
- (2011) J C Estrada et al. CELL DEATH AND DIFFERENTIATION
- Double Knockdown of Prolyl Hydroxylase and Factor-Inhibiting Hypoxia-Inducible Factor With Nonviral Minicircle Gene Therapy Enhances Stem Cell Mobilization and Angiogenesis After Myocardial Infarction
- (2011) M. Huang et al. CIRCULATION
- Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1
- (2011) Brian Hynes et al. EUROPEAN HEART JOURNAL
- Aging impairs the mobilization and homing of bone marrow-derived angiogenic cells to burn wounds
- (2011) Xianjie Zhang et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Increasing Vascularity to Improve Healing of a Segmental Defect of the Rat Femur
- (2011) Rena Stewart et al. JOURNAL OF ORTHOPAEDIC TRAUMA
- Constitutive HIF-1α Expression Blunts the Beneficial Effects of Cardiosphere-Derived Cell Therapy in the Heart by Altering Paracrine Factor Balance
- (2011) Michael Bonios et al. Journal of Cardiovascular Translational Research
- Evolution of oxygen utilization in multicellular organisms and implications for cell signalling in tissue engineering
- (2011) Katerina Stamati et al. Journal of Tissue Engineering
- Hypoxia. 1. Intracellular sensors for oxygen and oxidative stress: novel therapeutic targets
- (2010) Toshio Miyata et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Paracrine factors released by GATA-4 overexpressed mesenchymal stem cells increase angiogenesis and cell survival
- (2010) Hongxia Li et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Beneficial Effects of Desferrioxamine on Encapsulated Human Islets-In Vitro and In Vivo Study
- (2010) V. Vaithilingam et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Dual control: the HIF-2 regulator
- (2010) T. Lappin BLOOD
- Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche
- (2010) Ahmed Mohyeldin et al. Cell Stem Cell
- Roles of hypoxia-inducible factor-1α (HIF-1α) versus HIF-2α in the survival of hepatocellular tumor spheroids
- (2010) Heidi Menrad et al. HEPATOLOGY
- Chronic Inhibition of Hypoxia-inducible Factor Prolyl 4-hydroxylase Improves Ventricular Performance, Remodeling, and Vascularity After Myocardial Infarction in the Rat
- (2010) Weike Bao et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- The role of HIF prolyl hydroxylases in tumour growth
- (2010) Terhi Jokilehto et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Oxygen Sensing in Drosophila: Multiple Isoforms of the Prolyl Hydroxylase Fatiga Have Different Capacity to Regulate HIFα/Sima
- (2010) Julieta M. Acevedo et al. PLoS One
- Engineering vascularized tissues using natural and synthetic small molecules
- (2010) Lauren S. Sefcik et al. Organogenesis
- Cellular oxygen sensing: Importins and exportins are mediators of intracellular localisation of prolyl-4-hydroxylases PHD1 and PHD2
- (2009) Amrei Steinhoff et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mesenchymal stem cells cultured under hypoxia escape from senescence via down-regulation of p16 and extracellular signal regulated kinase
- (2009) Yonghui Jin et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Hepatocyte Growth Factor or Vascular Endothelial Growth Factor Gene Transfer Maximizes Mesenchymal Stem Cell-Based Myocardial Salvage After Acute Myocardial Infarction
- (2009) T. Deuse et al. CIRCULATION
- Cardiac Progenitor Cells and Biotinylated Insulin-Like Growth Factor-1 Nanofibers Improve Endogenous and Exogenous Myocardial Regeneration After Infarction
- (2009) M. Elena Padin-Iruegas et al. CIRCULATION
- Hypoxia inducible factor-2α: a critical mediator of aggressive tumor phenotypes
- (2009) Guoliang Qing et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Hypoxia induced paclitaxel resistance in human ovarian cancers via hypoxia-inducible factor 1α
- (2009) Lei Huang et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Prolyl hydroxylase inhibitor dimethyloxalylglycine enhances mesenchymal stem cell survival
- (2009) Xian-Bao Liu et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The role of oxygen in regulating neural stem cells in development and disease
- (2009) David M. Panchision JOURNAL OF CELLULAR PHYSIOLOGY
- Role of hypoxia-inducible factor-1α in angiogenic–osteogenic coupling
- (2009) Ryan C. Riddle et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice
- (2009) Xing Shen et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Critical limb ischemia
- (2009) Vinit N. Varu et al. JOURNAL OF VASCULAR SURGERY
- miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche
- (2009) Li-Chun Cheng et al. NATURE NEUROSCIENCE
- Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease
- (2009) Peter Fraisl et al. NATURE REVIEWS DRUG DISCOVERY
- Non-hypoxic Stabilization of Hypoxia-Inducible Factor Alpha (HIF-α): Relevance in Neural Progenitor/Stem Cells
- (2009) Javorina Milosevic et al. NEUROTOXICITY RESEARCH
- Synergistic effect of HIF-1 gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
- (2009) S. Rey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Improving outcome of transplanted mesenchymal stem cells for ischemic heart disease
- (2008) Rui-Zhen Shi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Promotion of osteogenesis through β-catenin signaling by desferrioxamine
- (2008) Zhi-Hu Qu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Transplantation of human neural stem cells protect against ischemia in a preventive mode via hypoxia-inducible factor-1α stabilization in the host brain
- (2008) Kon Chu et al. BRAIN RESEARCH
- Role and regulation of prolyl hydroxylase domain proteins
- (2008) G-H Fong et al. CELL DEATH AND DIFFERENTIATION
- Biology of HIF-1α
- (2008) A Weidemann et al. CELL DEATH AND DIFFERENTIATION
- PHDs overactivation during chronic hypoxia "desensitizes" HIF and protects cells from necrosis
- (2008) A. Ginouves et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activation of the hypoxia-inducible factor-1 pathway accelerates bone regeneration
- (2008) C. Wan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypoxic Preconditioning Results in Increased Motility and Improved Therapeutic Potential of Human Mesenchymal Stem Cells
- (2008) Ivana Rosová et al. STEM CELLS
- Overexpression of Vascular Endothelial Growth Factor In Vitro Using Deferoxamine: A New Drug to Increase Islet Vascularization During Transplantation
- (2008) A. Langlois et al. TRANSPLANTATION PROCEEDINGS
- Prolyl 4-hydroxylase activity-responsive transcription factors: From hydroxylation to gene expression and neuroprotection
- (2007) Ambreena Siddiq Frontiers in Bioscience-Landmark
- No place like home: anatomy and function of the stem cell niche
- (2007) D. Leanne Jones et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A brief definition of regenerative medicine
- (2007) Chris Mason et al. Regenerative Medicine
- Mesenchymal Stem Cells Cooperate with Bone Marrow Cells in Therapy of Diabetes
- (2007) Veronika S. Urbán et al. STEM CELLS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now