Single-cell dissection of transcriptional heterogeneity in human colon tumors

The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse

(2011) Anna Merlos-Suárez et al.   Cell Stem Cell

High-throughput microfluidic single-cell RT-qPCR

(2011) A. K. White et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt Proteins Are Self-Renewal Factors for Mammary Stem Cells and Promote Their Long-Term Expansion in Culture

(2010) Yi Arial Zeng et al.   Cell Stem Cell

Tumor-Initiating Cells Are Rare in Many Human Tumors

(2010) Kota Ishizawa et al.   Cell Stem Cell

Resolution of Cell Fate Decisions Revealed by Single-Cell Gene Expression Analysis from Zygote to Blastocyst

(2010) Guoji Guo et al.   DEVELOPMENTAL CELL

Microsatellite instability as a marker of prognosis and response to therapy: A meta-analysis of colorectal cancer survival data

(2010) Cecilia Guastadisegni et al.   EUROPEAN JOURNAL OF CANCER

Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype

(2010) So Yeon Park et al.   JOURNAL OF CLINICAL INVESTIGATION

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

(2010) Toshiro Sato et al.   NATURE

Adjuvant Chemotherapy for Resected Stage II and III Colon Cancer: Comparison of Two Widely Used Prognostic Calculators

(2010) Aditya Bardia et al.   SEMINARS IN ONCOLOGY

Ezh2 Orchestrates Gene Expression for the Stepwise Differentiation of Tissue-Specific Stem Cells

(2009) Elena Ezhkova et al.   CELL

Transcription Factor Achaete Scute-Like 2 Controls Intestinal Stem Cell Fate

(2009) Laurens G. van der Flier et al.   CELL

Heterogeneity in Cancer: Cancer Stem Cells versus Clonal Evolution

(2009) Mark Shackleton et al.   CELL

Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis

(2009) Kim B. Jensen et al.   Cell Stem Cell

DLL4 Blockade Inhibits Tumor Growth and Reduces Tumor-Initiating Cell Frequency

(2009) Timothy Hoey et al.   Cell Stem Cell

Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer

(2009) R. N. Jorissen et al.   CLINICAL CANCER RESEARCH

SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells

(2009) Taeko K. Noah et al.   EXPERIMENTAL CELL RESEARCH

The Ets-Domain Transcription Factor Spdef Promotes Maturation of Goblet and Paneth Cells in the Intestinal Epithelium

(2009) Alex Gregorieff et al.   GASTROENTEROLOGY

Experimentally Derived Metastasis Gene Expression Profile Predicts Recurrence and Death in Patients With Colon Cancer

(2009) J. Joshua Smith et al.   GASTROENTEROLOGY

Pathologic Evaluation of Unknown Primary Cancer

(2009) Karin A. Oien   SEMINARS IN ONCOLOGY

MS4A12 Is a Colon-Selective Store-Operated Calcium Channel Promoting Malignant Cell Processes

(2008) M. Koslowski et al.   CANCER RESEARCH

A Stochastic Model for Cancer Stem Cell Origin in Metastatic Colon Cancer

(2008) C. Odoux et al.   CANCER RESEARCH

Chemokines and chemokine receptors in stem cell circulation

(2008) Katia Beider   Frontiers in Bioscience-Landmark

Differential diagnostic and functional role of the multi-marker phenotype CDX2/CK20/CK7 in colorectal cancer stratified by mismatch repair status

(2008) Alessandro Lugli et al.   MODERN PATHOLOGY

Efficient tumour formation by single human melanoma cells

(2008) Elsa Quintana et al.   NATURE

What is principal component analysis?

(2008) Markus Ringnér   NATURE BIOTECHNOLOGY

Bmi1 is expressed in vivo in intestinal stem cells

(2008) Eugenio Sangiorgi et al.   NATURE GENETICS

DNA bar coding and pyrosequencing to analyze adverse events in therapeutic gene transfer

(2008) Gary P. Wang et al.   NUCLEIC ACIDS RESEARCH

Serrated Adenoma of the Colorectum Undergoes a Proliferation versus Differentiation Process: New Conceptual Interpretation of Morphogenesis

(2008) Yu-Fei Jiao et al.   ONCOLOGY

Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity

(2008) L. Vermeulen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunostaining of Lgr5, an Intestinal Stem Cell Marker, in Normal and Premalignant Human Gastrointestinal Tissue

(2008) Laren Becker et al.   TheScientificWorldJOURNAL

Boolean implication networks derived from large scale, whole genome microarray datasets

(2008) Debashis Sahoo et al.   GENOME BIOLOGY