The role of the endoplasmic reticulum protein calreticulin in mediating TGF-β-stimulated extracellular matrix production in fibrotic disease

Calreticulin regulates TGF-β1-induced epithelial mesenchymal transition through modulating Smad signaling and calcium signaling

(2017) Yanjiao Wu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Calreticulin Is Required for TGF-β-Induced Epithelial-to-Mesenchymal Transition during Cardiogenesis in Mouse Embryonic Stem Cells

(2017) Fereshteh Karimzadeh et al.   Stem Cell Reports

Inhibition of the Unfolded Protein Response Mechanism Prevents Cardiac Fibrosis

(2016) Jody Groenendyk et al.   PLoS One

Calreticulin Regulates Neointima Formation and Collagen Deposition following Carotid Artery Ligation

(2015) Kurt A. Zimmerman et al.   JOURNAL OF VASCULAR RESEARCH

Valproate attenuates diabetic nephropathy through inhibition of endoplasmic reticulum stress-induced apoptosis

(2015) XIN-YI SUN et al.   Molecular Medicine Reports

Oleanolic acid andN-acetylcysteine ameliorate diabetic nephropathy through reduction of oxidative stress and endoplasmic reticulum stress in a type 2 diabetic rat model

(2015) Eun Soo Lee et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Calreticulin is required for development of the cumulus oocyte complex and female fertility

(2015) Keizo Tokuhiro et al.   Scientific Reports

Reversal of fibrosis by TGF-β3 in a 3D in vitro model

(2014) D. Karamichos et al.   EXPERIMENTAL EYE RESEARCH

Epithelial Calreticulin Up-Regulation Promotes Profibrotic Responses and Tubulointerstitial Fibrosis Development

(2013) Niki Prakoura et al.   AMERICAN JOURNAL OF PATHOLOGY

Asbestos-Induced Alveolar Epithelial Cell Apoptosis. The Role of Endoplasmic Reticulum Stress Response

(2013) David W. Kamp et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Sodium tauroursodeoxycholate prevents paraquat-induced cell death by suppressing endoplasmic reticulum stress responses in human lung epithelial A549 cells

(2013) Tomohiro Omura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NFAT2 inhibitor ameliorates diabetic nephropathy and podocyte injury indb/dbmice

(2013) Li Zhang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Calreticulin Regulates Transforming Growth Factor-β-stimulated Extracellular Matrix Production

(2013) Kurt A. Zimmerman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of 150-kDa oxygen-regulated protein (ORP150) stimulates bleomycin-induced pulmonary fibrosis and dysfunction in mice

(2012) Ken-Ichiro Tanaka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endoplasmic reticulum stress as a pro-fibrotic stimulus

(2012) Harikrishna Tanjore et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A novel cellular stress response characterised by a rapid reorganisation of membranes of the endoplasmic reticulum

(2012) S Varadarajan et al.   CELL DEATH AND DIFFERENTIATION

The role of endoplasmic reticulum stress and the unfolded protein response in fibrosis

(2012) Stefania Lenna et al.   CURRENT OPINION IN RHEUMATOLOGY

CDK5 and MEKK1 mediate pro-apoptotic signalling following endoplasmic reticulum stress in an autosomal dominant retinitis pigmentosa model

(2012) Min-Ji Kang et al.   NATURE CELL BIOLOGY

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Phenylbutyric acid protects against carbon tetrachloride-induced hepatic fibrogenesis in mice

(2012) Jian-Qing Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Exogenous calreticulin improves diabetic wound healing

(2012) Matthew R. Greives et al.   WOUND REPAIR AND REGENERATION

Involvement of Endoplasmic Reticulum Stress in Myofibroblastic Differentiation of Lung Fibroblasts

(2011) Hyun Ah Baek et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Attenuation of endoplasmic reticulum stress using the chemical chaperone 4-phenylbutyric acid prevents cardiac fibrosis induced by isoproterenol

(2011) Pedro Ayala et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Alveolar Epithelial Cells Undergo Epithelial-to-Mesenchymal Transition in Response to Endoplasmic Reticulum Stress

(2011) Harikrishna Tanjore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alteration of integrin-dependent adhesion and signaling in EMT-like MDCK cells established through overexpression of calreticulin

(2011) Yoshito Ihara et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

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(2011) Chih-Kang Chiang et al.   MOLECULAR MEDICINE

Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs

(2011) W. E. Lawson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

The Calreticulin-Binding Sequence of Thrombospondin 1 Regulates Collagen Expression and Organization During Tissue Remodeling

(2010) Mariya T. Sweetwyne et al.   AMERICAN JOURNAL OF PATHOLOGY

Structural Insight into the Role of Thrombospondin-1 Binding to Calreticulin in Calreticulin-Induced Focal Adhesion Disassembly

(2010) Qi Yan et al.   BIOCHEMISTRY

The Role of Endoplasmic Reticulum Stress in the Progression of Atherosclerosis

(2010) Ira Tabas   CIRCULATION RESEARCH

Intracellular Calreticulin Regulates Multiple Steps in Fibrillar Collagen Expression, Trafficking, and Processing into the Extracellular Matrix

(2010) Lauren Van Duyn Graham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Mechanism of Release of Calreticulin from Cells During Apoptosis

(2010) Joanna M. Tarr et al.   JOURNAL OF MOLECULAR BIOLOGY

Evidence Supporting a Role for Endoplasmic Reticulum Stress in the Development of Atherosclerosis in a Hyperglycaemic Mouse Model

(2009) Mohammad I. Khan et al.   ANTIOXIDANTS & REDOX SIGNALING

Calreticulin, a multi-process calcium-buffering chaperone of the endoplasmic reticulum

(2009) Marek Michalak et al.   BIOCHEMICAL JOURNAL

Aortic ER Stress in Streptozotocin-Induced Diabetes Mellitus in APA Hamsters

(2009) Masaki KUROKAWA et al.   EXPERIMENTAL ANIMALS

Calreticulin: non-endoplasmic reticulum functions in physiology and disease

(2009) Leslie I. Gold et al.   FASEB JOURNAL

Endoplasmic reticulum stress in proteinuric kidney disease

(2009) Andrey V. Cybulsky   KIDNEY INTERNATIONAL

Calreticulin Enhances Porcine Wound Repair by Diverse Biological Effects

(2008) Lillian B. Nanney et al.   AMERICAN JOURNAL OF PATHOLOGY

Epithelial Endoplasmic Reticulum Stress and Apoptosis in Sporadic Idiopathic Pulmonary Fibrosis

(2008) Martina Korfei et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

How IRE1 Reacts to ER Stress

(2008) David Ron et al.   CELL

Endoplasmic reticulum stress in the kidney

(2008) Masanori Kitamura   Clinical and Experimental Nephrology

Kinase-dependent adhesion to fibronectin: Regulation by calreticulin

(2008) Sylvia Papp et al.   EXPERIMENTAL CELL RESEARCH

Thrombospondin 1 binding to calreticulin-LRP1 signals resistance to anoikis

(2008) Manuel A. Pallero et al.   FASEB JOURNAL

Involvement of Epithelial Cell Apoptosis in Interstitial Lung Diseases

(2008) Kazuyoshi Kuwano   INTERNAL MEDICINE

ER stress is associated with dedifferentiation and an epithelial-to-mesenchymal transition-like phenotype in PC Cl3 thyroid cells

(2008) Luca Ulianich et al.   JOURNAL OF CELL SCIENCE

Proteinuria and Hyperglycemia Induce Endoplasmic Reticulum Stress

(2008) M. T. Lindenmeyer et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

(2008) Inki Kim et al.   NATURE REVIEWS DRUG DISCOVERY

Altered expression of calreticulin during the development of fibrosis

(2008) Katerina P. Kypreou et al.   PROTEOMICS