Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

A specific pathway inducing autophagic cell death is marked by an IP3R mutation

(2014) David Lam et al.   Autophagy

Prion Diseases: From Protein to Cell Pathology

(2008) Gabor G. Kovacs et al.   AMERICAN JOURNAL OF PATHOLOGY

Development of a novel fluorescent probe for fluorescence correlation spectroscopic detection of kinase inhibitors

(2008) Mitsuyasu Kawaguchi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Protein quality control in the early secretory pathway

(2008) Tiziana Anelli et al.   EMBO JOURNAL

Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins

(2008) Sami Reijonen et al.   EXPERIMENTAL CELL RESEARCH

ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1

(2008) H. Nishitoh et al.   GENES & DEVELOPMENT

Therapeutic Gene Silencing Delivered by a Chemically Modified Small Interfering RNA against Mutant SOD1 Slows Amyotrophic Lateral Sclerosis Progression

(2008) Hongyan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BI-1 Regulates Endoplasmic Reticulum Ca2+Homeostasis Downstream of Bcl-2 Family Proteins

(2008) Chunyan Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordination of Growth and Endoplasmic Reticulum Stress Signaling by Regulator of Calcineurin 1 (RCAN1), a Novel ATF6-inducible Gene

(2008) Peter J. Belmont et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Kinase Cθ Is Required for Autophagy in Response to Stress in the Endoplasmic Reticulum

(2008) Kenjiro Sakaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chop deletion reduces oxidative stress, improves β cell function, and promotes cell survival in multiple mouse models of diabetes

(2008) Benbo Song et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis

(2008) Kirsten Neubert et al.   NATURE MEDICINE

The ER-Bound RING Finger Protein 5 (RNF5/RMA1) Causes Degenerative Myopathy in Transgenic Mice and Is Deregulated in Inclusion Body Myositis

(2008) Agnès Delaunay et al.   PLoS One

Carboxypeptidase E mediates palmitate-induced  -cell ER stress and apoptosis

(2008) K. D. Jeffrey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Hepatic Lipogenesis by the Transcription Factor XBP1

(2008) A.-H. Lee et al.   SCIENCE

The role of the unfolded protein response in the heart

(2007) Christopher C. Glembotski   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Carnosic acid, acatechol-typeelectrophilic compound, protects neurons bothin vitroandin vivothrough activation of the Keap1/Nrf2 pathway viaS-alkylation of targeted cysteines on Keap1

(2007) Takumi Satoh et al.   JOURNAL OF NEUROCHEMISTRY