NFAT2 inhibitor ameliorates diabetic nephropathy and podocyte injury indb/dbmice

NFAT2 mediates high glucose-induced glomerular podocyte apoptosis through increased Bax expression

(2013) Ruizhao Li et al.   EXPERIMENTAL CELL RESEARCH

Role of Intensive Glucose Control in Development of Renal End Points in Type 2 Diabetes Mellitus

(2012) Steven G. Coca et al.   ARCHIVES OF INTERNAL MEDICINE

The calcineurin–NFAT pathway allows for urokinase receptor-mediated beta3 integrin signaling to cause podocyte injury

(2012) Bin Zhang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Genipin Inhibits Mitochondrial Uncoupling Protein 2 Expression and Ameliorates Podocyte Injury in Diabetic Mice

(2012) Wenjing Qiu et al.   PLoS One

Angiotensin II Contributes to Podocyte Injury by Increasing TRPC6 Expression via an NFAT-Mediated Positive Feedback Signaling Pathway

(2011) Tom Nijenhuis et al.   AMERICAN JOURNAL OF PATHOLOGY

Reno-protective effects of renin–angiotensin system blockade in type 2 diabetic patients: a systematic review and network meta-analysis

(2011) P. Vejakama et al.   DIABETOLOGIA

The targeted podocyte

(2011) Agnes B. Fogo   JOURNAL OF CLINICAL INVESTIGATION

Calcineurin (CN) Activation Promotes Apoptosis of Glomerular Podocytes Bothin Vitroandin Vivo

(2011) Liming Wang et al.   MOLECULAR ENDOCRINOLOGY

Amiloride off-target effect inhibits podocyte urokinase receptor expression and reduces proteinuria

(2011) B. Zhang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Spironolactone inhibits hyperglycemia-induced podocyte injury by attenuating ROS production

(2011) J. Toyonaga et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activation of a nuclear factor of activated T-lymphocyte-3 (NFAT3) by oxidative stress in carboplatin-mediated renal apoptosis

(2010) Heng Lin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Approach to the Patient with Type 2 Diabetes and Progressive Kidney Disease

(2010) Elizabeth R. Seaquist et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Diabetic kidney disease: act now or pay later

(2010) Robert C. Atkins et al.   Journal of the American Society of Hypertension

Activation of NFAT Signaling in Podocytes Causes Glomerulosclerosis

(2010) Y. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TRPC6 mutations associated with focal segmental glomerulosclerosis cause constitutive activation of NFAT-dependent transcription

(2009) Johannes Schlöndorff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Regulation of cell signalling by uPAR

(2009) Harvey W. Smith et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Epithelial-to-Mesenchymal Transition Is a Potential Pathway Leading to Podocyte Dysfunction and Proteinuria

(2008) Yingjian Li et al.   AMERICAN JOURNAL OF PATHOLOGY