Modulation of Multiple Sclerosis and Its Animal Model Experimental Autoimmune Encephalomyelitis by Food and Gut Microbiota

1,25-dihydroxyvitamin D3 -induced dendritic cells suppress experimental autoimmune encephalomyelitis by increasing proportions of the regulatory lymphocytes and reducing T helper type 1 and type 17 cells

(2017) Zhongxiang Xie et al.   IMMUNOLOGY

Gut microbiota interactions with the immunomodulatory role of vitamin D in normal individuals

(2017) Renata V. Luthold et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Interactions between the microbiota, immune and nervous systems in health and disease

(2017) Thomas C Fung et al.   NATURE NEUROSCIENCE

The influence of gut-derived CD39 regulatory T cells in CNS demyelinating disease

(2017) Javier Ochoa-Repáraz et al.   Translational Research

Natural Docosahexaenoic Acid in the Triglyceride Form Attenuates In Vitro Microglial Activation and Ameliorates Autoimmune Encephalomyelitis in Mice

(2017) Pilar Mancera et al.   Nutrients

The enteric nervous system promotes intestinal health by constraining microbiota composition

(2017) Annah S. Rolig et al.   PLOS BIOLOGY

Protein- and zinc-deficient diets modulate the murine microbiome and metabolic phenotype

(2016) J. Mayneris-Perxachs et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Peptidoglycan from the gut microbiota governs the lifespan of circulating phagocytes at homeostasis

(2016) C. B. Hergott et al.   BLOOD

Associations between the gut microbiota and host immune markers in pediatric multiple sclerosis and controls

(2016) Helen Tremlett et al.   BMC Neurology

A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

(2016) Mahesh S. Desai et al.   CELL

Prebiotics and synbiotics

(2016) Janina A. Krumbeck et al.   CURRENT OPINION IN GASTROENTEROLOGY

Gut microbiota in early pediatric multiple sclerosis: a case−control study

(2016) H. Tremlett et al.   EUROPEAN JOURNAL OF NEUROLOGY

High salt drives Th17 responses in experimental autoimmune encephalomyelitis without impacting myeloid dendritic cells

(2016) Stefanie Jörg et al.   EXPERIMENTAL NEUROLOGY

Communicating systems in the body: how microbiota and microglia cooperate

(2016) Daniel Erny et al.   IMMUNOLOGY

Emerging Concepts on the Gut Microbiome and Multiple Sclerosis

(2016) Justin D. Glenn et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Induction of regulatory T cells in Th1-/Th17-driven experimental autoimmune encephalomyelitis by zinc administration

(2016) Eva Rosenkranz et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Gut microbiota composition and relapse risk in pediatric MS: A pilot study

(2016) Helen Tremlett et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

The bacterial peptidoglycan-sensing molecule Pglyrp2 modulates brain development and behavior

(2016) T Arentsen et al.   MOLECULAR PSYCHIATRY

Diet: Changing the recipe

(2016) Sujata Gupta   NATURE

Normalizing the environment recapitulates adult human immune traits in laboratory mice

(2016) Lalit K. Beura et al.   NATURE

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

(2016) Veit Rothhammer et al.   NATURE MEDICINE

Gram-positive bacteria are held at a distance in the colon mucus by the lectin-like protein ZG16

(2016) Joakim H. Bergström et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Healthy human gut phageome

(2016) Pilar Manrique et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut environment-induced intraepithelial autoreactive CD4+ T cells suppress central nervous system autoimmunity via LAG-3

(2016) Atsushi Kadowaki et al.   Nature Communications

Alterations of the human gut microbiome in multiple sclerosis

(2016) Sushrut Jangi et al.   Nature Communications

A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms

(2016) In Young Choi et al.   Cell Reports

Role of Vitamin D in the Hygiene Hypothesis: The Interplay between Vitamin D, Vitamin D Receptors, Gut Microbiota, and Immune Response

(2016) Allison Clark et al.   Frontiers in Immunology

Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls

(2016) Jun Chen et al.   Scientific Reports

Brain microbiota disruption within inflammatory demyelinating lesions in multiple sclerosis

(2016) W. G. Branton et al.   Scientific Reports

Murine Gut Microbiota—Diet Trumps Genes

(2015) Jens Walter   Cell Host & Microbe

The Gut Microbiome in Multiple Sclerosis

(2015) Daniel W. Mielcarz et al.   Current Treatment Options in Neurology

A basic overview of multiple sclerosis immunopathology

(2015) N. Grigoriadis et al.   EUROPEAN JOURNAL OF NEUROLOGY

Animal models of Multiple Sclerosis

(2015) Claudio Procaccini et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Exacerbation of autoimmune neuroinflammation by dietary sodium is genetically controlled and sex specific

(2015) Dimitry N. Krementsov et al.   FASEB JOURNAL

Identification of an anti-inflammatory protein fromFaecalibacterium prausnitzii, a commensal bacterium deficient in Crohn’s disease

(2015) E Quévrain et al.   GUT

Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine

(2015) Aiden Haghikia et al.   IMMUNITY

Gut Microbiota in Multiple Sclerosis

(2015) Brandi L. Cantarel et al.   JOURNAL OF INVESTIGATIVE MEDICINE

An endogenous nanomineral chaperones luminal antigen and peptidoglycan to intestinal immune cells

(2015) Jonathan J. Powell et al.   Nature Nanotechnology

Gut biogeography of the bacterial microbiota

(2015) Gregory P. Donaldson et al.   NATURE REVIEWS MICROBIOLOGY

“Disease modifying nutricals” for multiple sclerosis

(2015) Katja Schmitz et al.   PHARMACOLOGY & THERAPEUTICS

Role of the normal gut microbiota

(2015) Sai Manasa Jandhyala   WORLD JOURNAL OF GASTROENTEROLOGY

Dysbiosis in the Gut Microbiota of Patients with Multiple Sclerosis, with a Striking Depletion of Species Belonging to Clostridia XIVa and IV Clusters

(2015) Sachiko Miyake et al.   PLoS One

Oral zinc aspartate treats experimental autoimmune encephalomyelitis

(2014) Claudia Schubert et al.   BIOMETALS

Impact of dietary fatty acids on metabolic activity and host intestinal microbiota composition in C57BL/6J mice

(2014) Elaine Patterson et al.   BRITISH JOURNAL OF NUTRITION

Gut Microbiome and Multiple Sclerosis

(2014) Pavan Bhargava et al.   Current Neurology and Neuroscience Reports

CD8+MAIT cells infiltrate into the CNS and alterations in their blood frequencies correlate with IL-18 serum levels in multiple sclerosis

(2014) Anne Willing et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Retinoic Acid Increases Foxp3+ Regulatory T Cells and Inhibits Development of Th17 Cells by Enhancing TGF- -Driven Smad3 Signaling and Inhibiting IL-6 and IL-23 Receptor Expression

(2014) S. Xiao et al.   JOURNAL OF IMMUNOLOGY

Sodium intake is associated with increased disease activity in multiple sclerosis

(2014) Mauricio F Farez et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Gut microbiota are related to Parkinson's disease and clinical phenotype

(2014) Filip Scheperjans et al.   MOVEMENT DISORDERS

The association of diet with quality of life, disability, and relapse rate in an international sample of people with multiple sclerosis

(2014) Emily J Hadgkiss et al.   NUTRITIONAL NEUROSCIENCE

The Intestinal Archaea Methanosphaera stadtmanae and Methanobrevibacter smithii Activate Human Dendritic Cells

(2014) Corinna Bang et al.   PLoS One

B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes

(2014) J. N. H. Stern et al.   Science Translational Medicine

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

Commensal microbiota regulates T cell fate decision in the gut

(2014) Yukihiro Furusawa et al.   Seminars in Immunopathology

An intestinal commensal symbiosis factor controls neuroinflammation via TLR2-mediated CD39 signalling

(2014) Yan Wang et al.   Nature Communications

Non-myeloablative autologous haematopoietic stem cell transplantation expands regulatory cells and depletes IL-17 producing mucosal-associated invariant T cells in multiple sclerosis

(2013) Sofia V. Abrahamsson et al.   BRAIN

Amelioration of experimental autoimmune encephalomyelitis by probiotic mixture is mediated by a shift in T helper cell immune response

(2013) Ho-Keun Kwon et al.   CLINICAL IMMUNOLOGY

Immunomodulatory and therapeutic effects of Hot-nature diet and co-supplemented hemp seed, evening primrose oils intervention in multiple sclerosis patients

(2013) Soheila Rezapour-Firouzi et al.   COMPLEMENTARY THERAPIES IN MEDICINE

Remote control—triggering of brain autoimmune disease in the gut

(2013) Hartmut Wekerle et al.   CURRENT OPINION IN IMMUNOLOGY

Phage cocktails and the future of phage therapy

(2013) Benjamin K Chan et al.   Future Microbiology

Tocopherol Derivative TFA-12 Promotes Myelin Repair in Experimental Models of Multiple Sclerosis

(2013) B. Blanchard et al.   JOURNAL OF NEUROSCIENCE

Ethyl-eicosapentaenoic acid ameliorates the clinical course of experimental allergic encephalomyelitis induced in dark agouti rats

(2013) Serafina Salvati et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Microbiota is essential for social development in the mouse

(2013) L Desbonnet et al.   MOLECULAR PSYCHIATRY

Th17-cell plasticity in Helicobacter hepaticus–induced intestinal inflammation

(2013) P J Morrison et al.   Mucosal Immunology

Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1

(2013) Chuan Wu et al.   NATURE

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells

(2013) Markus Kleinewietfeld et al.   NATURE

The gastrointestinal mucus system in health and disease

(2013) Malin E. V. Johansson et al.   Nature Reviews Gastroenterology & Hepatology

Modeling the heterogeneity of multiple sclerosis in animals

(2013) Sarah B. Simmons et al.   TRENDS IN IMMUNOLOGY

ω-3 Fatty Acid Treatment in Multiple Sclerosis (OFAMS Study)

(2012) Øivind Torkildsen et al.   ARCHIVES OF NEUROLOGY

Zinc aspartate suppresses T cell activation in vitro and relapsing experimental autoimmune encephalomyelitis in SJL/J mice

(2012) Diana Stoye et al.   BIOMETALS

The domain Archaea in human mucosal surfaces

(2012) F. Matarazzo et al.   CLINICAL MICROBIOLOGY AND INFECTION

All-trans-retinoic acid ameliorates experimental allergic encephalomyelitis by affecting dendritic cell and monocyte development

(2012) Xiao-Xia Zhan et al.   IMMUNOLOGY

Hsp65-producing Lactococcus lactis prevents experimental autoimmune encephalomyelitis in mice by inducing CD4+LAP+ regulatory T cells

(2012) Rafael M. Rezende et al.   JOURNAL OF AUTOIMMUNITY

Eicosapentaenoic acid (EPA) induces peroxisome proliferator-activated receptors and ameliorates experimental autoimmune encephalomyelitis

(2012) Kiichi Unoda et al.   JOURNAL OF NEUROIMMUNOLOGY

Endotoxin- and ATP-neutralizing activity of alkaline phosphatase as a strategy to limit neuroinflammation

(2012) Ruth Huizinga et al.   Journal of Neuroinflammation

Animal models of multiple sclerosis: the good, the bad and the bottom line

(2012) Richard M Ransohoff   NATURE NEUROSCIENCE

Inflammation-Mediated Memory Dysfunction and Effects of a Ketogenic Diet in a Murine Model of Multiple Sclerosis

(2012) Do Young Kim et al.   PLoS One

Chapter 12: Human Microbiome Analysis

(2012) Xochitl C. Morgan et al.   PLoS Computational Biology

Effect of rituximab on human in vivo antibody immune responses

(2011) Mark D. Pescovitz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination

(2011) Kerstin Berer et al.   NATURE

Effect of diphenyl diselenide on the development of experimental autoimmune encephalomyelitis

(2011) Natalí L. Chanaday et al.   NEUROCHEMISTRY INTERNATIONAL

The Lactic Acid Bacterium Pediococcus acidilactici Suppresses Autoimmune Encephalomyelitis by Inducing IL-10-Producing Regulatory T Cells

(2011) Kazushiro Takata et al.   PLoS One

Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells

(2010) M. Dusseaux et al.   BLOOD

Docosahexaenoic acid prevents dendritic cell maturation, inhibits antigen-specific Th1/Th17 differentiation and suppresses experimental autoimmune encephalomyelitis

(2010) Weimin Kong et al.   BRAIN BEHAVIOR AND IMMUNITY

Zinc suppresses Th17 development via inhibition of STAT3 activation

(2010) Chika Kitabayashi et al.   INTERNATIONAL IMMUNOLOGY

Central Nervous System Demyelinating Disease Protection by the Human Commensal Bacteroides fragilis Depends on Polysaccharide A Expression

(2010) J. Ochoa-Reparaz et al.   JOURNAL OF IMMUNOLOGY

A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease

(2010) J Ochoa-Repáraz et al.   Mucosal Immunology

Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression

(2010) L. Desbonnet et al.   NEUROSCIENCE

A Novel Probiotic Mixture Exerts a Therapeutic Effect on Experimental Autoimmune Encephalomyelitis Mediated by IL-10 Producing Regulatory T Cells

(2010) Shahram Lavasani et al.   PLoS One

Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis

(2010) Y. K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunomodulatory effects of Vitamin D in multiple sclerosis

(2009) J. Correale et al.   BRAIN

Vitamins E and D3 Attenuate Demyelination and Potentiate Remyelination Processes of Hippocampal Formation of Rats Following Local Injection of Ethidium Bromide

(2009) Mahdi Goudarzvand et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Targeting the Human Microbiome With Antibiotics, Probiotics, and Prebiotics: Gastroenterology Enters the Metagenomics Era

(2009) Geoffrey A. Preidis et al.   GASTROENTEROLOGY

Role of Gut Commensal Microflora in the Development of Experimental Autoimmune Encephalomyelitis

(2009) J. Ochoa-Reparaz et al.   JOURNAL OF IMMUNOLOGY

NKT Cell-Dependent Amelioration of a Mouse Model of Multiple Sclerosis by Altering Gut Flora

(2008) Hiroaki Yokote et al.   AMERICAN JOURNAL OF PATHOLOGY

Effects ofBifidobacterium animalisadministered during lactation on allergic and autoimmune responses in rodents

(2008) J. Ezendam et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Chronic calorie restriction attenuates experimental autoimmune encephalomyelitis

(2008) Laura Piccio et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

(2008) Marc Veldhoen et al.   NATURE

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

(2008) Francisco J. Quintana et al.   NATURE

ATP drives lamina propria TH17 cell differentiation

(2008) Koji Atarashi et al.   NATURE

Commensal microbiota is fundamental for the development of inflammatory pain

(2008) F. A. Amaral et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Strain-dependent effects of probiotic lactobacilli on EAE autoimmunity

(2008) Catharina B.M. Maassen et al.   VACCINE

Archaeosome adjuvants: Immunological capabilities and mechanism(s) of action

(2008) Lakshmi Krishnan et al.   VACCINE